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Protein Ontology report - smad1 isoform 1 phosphorylated 1
PR:000000647 - http://purl.obolibrary.org/obo/PR_000000647
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000647   
  PRO namesmad1 isoform 1 phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:SMAD1/iso:1/Phos:1
Other: RELATED:BMP receptor-activated smad1
  Definition"A smad1 isoform 1 phosphorylated form in which the phosphorylation occurs at the C-terminal SSxS motif as a result of the activation of the bone morphogenetic protein (BMP) signaling pathway. Example: UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046." [PMID:9136927] 
  PRO Categorymodification 
  ParentPR:000000571 smad1 isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
modification


PR:000000647 smad1 isoform 1 phosphorylated 1
SMAD1/iso:1/Phos:1
Yes
organism-modification


PR:000026334 smad1 isoform 1 phosphorylated 1 (human)
hSMAD1/iso:1/Phos:1
Yes
organism-modification


PR:000026724 smad1 isoform 1 phosphorylated 1 (mouse)
mSMAD1/iso:1/Phos:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007165 signal transductionPR:000026334 hSMAD1/iso:1/Phos:1 PMID:9759503
GO:0008285 negative regulation of cell population proliferationPR:000026724 mSMAD1/iso:1/Phos:1 PMID:15899870
GO:0030509 BMP signaling pathwayPR:000026334 hSMAD1/iso:1/Phos:1 PMID:8653785
PR:000026724 mSMAD1/iso:1/Phos:1 PMID:12370310; PMID:15198985

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:000000647 SMAD1/iso:1/Phos:1 PMID:10708949
GO:0005515 protein bindingPR:000026724 mSMAD1/iso:1/Phos:1 PMID:14633973
PR:000026724 mSMAD1/iso:1/Phos:1 PMID:14633973
PR:000026724 mSMAD1/iso:1/Phos:1 PMID:14633973
GO:0046332 SMAD bindingPR:000026334 hSMAD1/iso:1/Phos:1 PMID:9136927

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000026334 hSMAD1/iso:1/Phos:1 PMID:11509558; PMID:9759503
PR:000026724 mSMAD1/iso:1/Phos:1 PMID:10504300; PMID:12151307; PMID:12370310
GO:0005667 transcription factor complexPR:000026724 mSMAD1/iso:1/Phos:1 PMID:14633973
GO:0005769 early endosomePR:000026724 mSMAD1/iso:1/Phos:1 PMID:17592637