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Protein Ontology report - smad1 isoform 1 phosphorylated 1
PR:000000647 - http://purl.obolibrary.org/obo/PR_000000647
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000000647   
  PRO namesmad1 isoform 1 phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:SMAD1/iso:1/Phos:1
Other: RELATED:BMP receptor-activated smad1
  Definition"A smad1 isoform 1 phosphorylated form in which the phosphorylation occurs at the C-terminal SSxS motif as a result of the activation of the bone morphogenetic protein (BMP) signaling pathway. Example: UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046." [PMID:9136927] 
  PRO Categorymodification 
  ParentPR:000000571 smad1 isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
modification


PR:000000647
smad1 isoform 1 phosphorylated 1
SMAD1/iso:1/Phos:1
"A smad1 isoform 1 phosphorylated form in which the phosphorylation occurs at the C-terminal SSxS motif as a result of the activation of the bone morphogenetic protein (BMP) signaling pathway. Example: UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046." [PMID:9136927]
Yes
organism-modification


PR:000026334
smad1 isoform 1 phosphorylated 1 (human)
hSMAD1/iso:1/Phos:1
"A smad1 isoform 1 phosphorylated 1 in human. UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046." [PRO:DAN, Reactome:R-HSA-201464, Reactome:R-HSA-201483]
Yes
organism-modification


PR:000026724
smad1 isoform 1 phosphorylated 1 (mouse)
mSMAD1/iso:1/Phos:1
"A smad1 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046." [PMID:10504300, PMID:12151307, PMID:12370310]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000000647 SMAD1/iso:1/Phos:1
Example: UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046		 enablesGO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10708949
PR:000026334 hSMAD1/iso:1/Phos:1
UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046		 acts_upstream_of_or_withinGO:0007165 signal transduction PMID:9759503
GO:0030509 BMP signaling pathway PMID:8653785
enablesGO:0046332 SMAD binding with PR:Q13485 deletion target in pancreatic carcinoma 4 (human) PMID:9136927
located_inGO:0005634 nucleus PMID:11509558; PMID:9759503
PR:000026724 mSMAD1/iso:1/Phos:1
UniProtKB:P70340-1, Ser-463/Ser-465, MOD:00046		 acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation PMID:15899870
GO:0030509 BMP signaling pathway PMID:12370310; PMID:15198985
enablesGO:0005515 protein binding with PR:Q04211 BTG family member 2 (mouse) PMID:14633973
GO:0005515 protein binding with PR:Q8BGV5 mZNF8 PMID:14633973
GO:0005515 protein binding with PR:Q9QZH6 Ecsit PMID:14633973
located_inGO:0005634 nucleus PMID:10504300; PMID:12151307; PMID:12370310
GO:0005667 transcription factor complex PMID:14633973
GO:0005769 early endosome PMID:17592637