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Protein Ontology report - smad2 isoform Long acetylated and phosphorylated 1
PR:000000649 -
http://purl.obolibrary.org/obo/PR_000000649
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000649
PRO name
smad2 isoform Long acetylated and phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
SMAD2/iso:Long/AcPhos:1
Other
:
EXACT:
smad2 sequence 1 acetylated-1 and phosphorylated-1
Definition
"A smad2 isoform Long acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated on a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example:
UniProtKB:Q15796-1
, Lys-19,
MOD:00064
|Ser-465/Ser-467,
MOD:00046
." [
PMID:17074756
]
PRO Category
modification
Parent
PR:000000572
smad2 isoform Long acetylated and phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000000649
smad2 isoform Long acetylated and phosphorylated 1
SMAD2/iso:Long/AcPhos:1
"A smad2 isoform Long acetylated and phosphorylated form in which the phosphorylation occurs upon TGF-beta receptor activation and which has been further acetylated on a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756]
organism-modification
PR:000036554
smad2 isoform Long acetylated and phosphorylated 1 (human)
hSMAD2/iso:Long/AcPhos:1
"A smad2 isoform Long acetylated and phosphorylated 1 in human. UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046." [PMID:17074756, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036554
hSMAD2/iso:Long/AcPhos:1
UniProtKB:Q15796-1, Lys-19, MOD:00064|Ser-465/Ser-467, MOD:00046
acts_upstream_of_or_within
GO:0006355
regulation of DNA-templated transcription
PMID:17074756
GO:0007165
signal transduction
PMID:17074756
located_in
GO:0005634
nucleus
PMID:17074756