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Protein Ontology report - smad2 isoform Long phosphorylated 2
PR:000000651 -
http://purl.obolibrary.org/obo/PR_000000651
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000651
PRO name
smad2 isoform Long phosphorylated 2
Synonyms
PRO-Short-label
:
EXACT:
SMAD2/iso:Long/Phos:2
Definition
"A smad2 isoform Long phosphorylated form in which the phosphorylation occurs at the N-terminal Px[ST]P motif and multiple Ser and/or Thr residues in the linker region by ERK1. Example:
UniProtKB:Q15796-1
, Thr-8/Thr-220,
MOD:00047
|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467,
MOD:00046
." [
PMID:12193595
]
PRO Category
modification
Parent
PR:000000574
smad2 isoform Long phosphorylated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000000651
smad2 isoform Long phosphorylated 2
SMAD2/iso:Long/Phos:2
Yes
organism-modification
PR:000025935
smad2 isoform Long phosphorylated 2 (human)
hSMAD2/iso:Long/Phos:2
Yes
Yes
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SMAD2/iso:Long/Phos:2
forms found in complexes
SMAD2/iso:Long/Phos:2
Component
Complexes
PR:000000651
SMAD2/iso:Long/Phos:2
PR:000025969
smad2-smad4 protein complex 3
PR:000025935
hSMAD2/iso:Long/Phos:2
PR:000025946
smad2-smad4 protein complex 3 (human)
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006355
regulation of DNA-templated transcription
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
GO:0007165
signal transduction
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
GO:0060395
SMAD protein signal transduction
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
GO:0003712
transcription coregulator activity
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
GO:0046332
SMAD binding
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634
nucleus
PR:000025935
hSMAD2/iso:Long/Phos:2
PMID:12193595
;
PMID:17074053