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Protein Ontology report - smad2 isoform Long phosphorylated and ubiquitinated 1
PR:000000654 -
http://purl.obolibrary.org/obo/PR_000000654
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000654
PRO name
smad2 isoform Long phosphorylated and ubiquitinated 1
Synonyms
PRO-Short-label
:
EXACT:
SMAD2/iso:Long/PhosUbiq:1
Definition
"A smad2 isoform Long phosphorylated and ubiquitinated form that has been phosphorylated by TGF-beta receptor activation and further ubiquitinated by NEDD4L. This form is targeted for proteosomal degradation. Example:
UniProtKB:Q62432-1
, Ser-465/Ser-467,
MOD:00046
|
MOD:01148
." [
PMID:15496141
]
PRO Category
modification
Parent
PR:000000573
smad2 isoform Long phosphorylated and ubiquitinated form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000000654
smad2 isoform Long phosphorylated and ubiquitinated 1
SMAD2/iso:Long/PhosUbiq:1
"A smad2 isoform Long phosphorylated and ubiquitinated form that has been phosphorylated by TGF-beta receptor activation and further ubiquitinated by NEDD4L. This form is targeted for proteosomal degradation. Example: UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141]
organism-modification
PR:000036555
smad2 isoform Long phosphorylated and ubiquitinated 1 (mouse)
mSMAD2/iso:Long/PhosUbiq:1
"A smad2 isoform Long phosphorylated and ubiquitinated 1 in mouse. UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148." [PMID:15496141, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036555
mSMAD2/iso:Long/PhosUbiq:1
UniProtKB:Q62432-1, Ser-465/Ser-467, MOD:00046|MOD:01148
acts_upstream_of_or_within
GO:0007165
signal transduction
PMID:15496141
enables
NOT
GO:0003713
transcription coactivator activity
PMID:15496141
