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Protein Ontology report - smad2 isoform Short acetylated and phosphorylated 1
PR:000000655 - http://purl.obolibrary.org/obo/PR_000000655
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000000655   
  PRO namesmad2 isoform Short acetylated and phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:SMAD2/iso:Short/AcPhos:1
  Definition"A smad2 isoform Short acetylated and phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation and acetylated in a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756
  PRO Categorymodification 
  ParentPR:000000575 smad2 isoform Short acetylated and phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
modification



PR:000000655 smad2 isoform Short acetylated and phosphorylated 1

SMAD2/iso:Short/AcPhos:1


organism-modification



PR:000036556 smad2 isoform Short acetylated and phosphorylated 1 (human)

hSMAD2/iso:Short/AcPhos:1

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000036556 hSMAD2/iso:Short/AcPhos:1 PMID:17074756

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0003677 DNA bindingPR:000036556 hSMAD2/iso:Short/AcPhos:1 PMID:17074756
GO:0003700 DNA-binding transcription factor activityPR:000036556 hSMAD2/iso:Short/AcPhos:1 PMID:17074756