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Protein Ontology report - ezrin
PR:000001031 - http://purl.obolibrary.org/obo/PR_000001031
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001031   
  PRO nameezrin 
  Synonyms
PRO-Short-label: EXACT:EZR
Gene-based: RELATED:VIL2
Other: EXACT:cytovillin | villin-2
  Definition"An erm protein that is a translation product of the human EZR gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001030 erm protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 8                                        
         Modification9                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
gene


PR:000001031 ezrin
EZR

organism-gene


PR:P15311 ezrin (human)
hEZR

organism-sequence


PR:P15311-1 ezrin isoform 1 (human)
hEZR/iso:1

organism-modification


PR:000036588 ezrin isoform 1 phosphorylated 1 (human)
hEZR/iso:1/Phos:1

organism-modification


PR:000036589 ezrin isoform 1 phosphorylated 2 (human)
hEZR/iso:1/Phos:2
Yes
organism-modification


PR:000036590 ezrin isoform 1 phosphorylated 3 (human)
hEZR/iso:1/Phos:3
Yes
organism-modification


PR:000036591 ezrin isoform 1 phosphorylated 4 (human)
hEZR/iso:1/Phos:4

organism-modification


PR:000036592 ezrin isoform 1 phosphorylated 5 (human)
hEZR/iso:1/Phos:5
Yes
organism-modification


PR:000036625 ezrin isoform 1 phosphorylated 6 (human)
hEZR/iso:1/Phos:6
Yes
organism-modification


PR:000047345 ezrin, initiator methionine removed phosphorylated 5 (human)
hEZR/InitMet-/Phos:5

organism-modification


PR:000047346 ezrin, initiator methionine removed phosphorylated 1 (human)
hEZR/InitMet-/Phos:1

organism-gene


PR:P26040 ezrin (mouse)
mEZR

organism-sequence


PR:P26040-1 ezrin isoform 1 (mouse)
mEZR/iso:1

organism-modification


PR:000044790 ezrin isoform 1 phosphorylated 5 (mouse)
mEZR/iso:1/Phos:5

organism-gene


PR:P31977 ezrin (rat)
rEZR

organism-sequence


PR:P31977-1 ezrin isoform 1 (rat)
rEZR/iso:1

organism-gene


PR:P46150 moesin/ezrin/radixin homolog 1 (fruit fly)
fly-EZR

organism-sequence


PR:P46150-1 moesin/ezrin/radixin homolog 1 isoform J (fruit fly)
fly-EZR/iso:J

organism-sequence


PR:P46150-2 moesin/ezrin/radixin homolog 1 isoform D (fruit fly)
fly-EZR/iso:D

organism-sequence


PR:P46150-3 moesin/ezrin/radixin homolog 1 isoform A (fruit fly)
fly-EZR/iso:A

organism-sequence


PR:P46150-4 moesin/ezrin/radixin homolog 1 isoform B (fruit fly)
fly-EZR/iso:B

organism-sequence


PR:P46150-5 moesin/ezrin/radixin homolog 1 isoform C (fruit fly)
fly-EZR/iso:C

sequence


PR:000001032 ezrin isoform 1
EZR/iso:1

organism-sequence


PR:P15311-1 ezrin isoform 1 (human)
hEZR/iso:1

organism-modification


PR:000036588 ezrin isoform 1 phosphorylated 1 (human)
hEZR/iso:1/Phos:1

organism-modification


PR:000036589 ezrin isoform 1 phosphorylated 2 (human)
hEZR/iso:1/Phos:2
Yes
organism-modification


PR:000036590 ezrin isoform 1 phosphorylated 3 (human)
hEZR/iso:1/Phos:3
Yes
organism-modification


PR:000036591 ezrin isoform 1 phosphorylated 4 (human)
hEZR/iso:1/Phos:4

organism-modification


PR:000036592 ezrin isoform 1 phosphorylated 5 (human)
hEZR/iso:1/Phos:5
Yes
organism-modification


PR:000036625 ezrin isoform 1 phosphorylated 6 (human)
hEZR/iso:1/Phos:6
Yes
organism-sequence


PR:P26040-1 ezrin isoform 1 (mouse)
mEZR/iso:1

organism-modification


PR:000044790 ezrin isoform 1 phosphorylated 5 (mouse)
mEZR/iso:1/Phos:5

organism-sequence


PR:P31977-1 ezrin isoform 1 (rat)
rEZR/iso:1

modification


PR:000001033 ezrin isoform 1 phosphorylated form
EZR/iso:1/PhosRes+

modification


PR:000001034 ezrin isoform 1 phosphorylated 1
EZR/iso:1/Phos:1

organism-modification


PR:000036588 ezrin isoform 1 phosphorylated 1 (human)
hEZR/iso:1/Phos:1

modification


PR:000001035 ezrin isoform 1 phosphorylated 2
EZR/iso:1/Phos:2

organism-modification


PR:000036589 ezrin isoform 1 phosphorylated 2 (human)
hEZR/iso:1/Phos:2
Yes
modification


PR:000001038 ezrin isoform 1 phosphorylated 3
EZR/iso:1/Phos:3

organism-modification


PR:000036590 ezrin isoform 1 phosphorylated 3 (human)
hEZR/iso:1/Phos:3
Yes
modification


PR:000001039 ezrin isoform 1 phosphorylated 4
EZR/iso:1/Phos:4

organism-modification


PR:000036591 ezrin isoform 1 phosphorylated 4 (human)
hEZR/iso:1/Phos:4

modification


PR:000001040 ezrin isoform 1 phosphorylated 5
EZR/iso:1/Phos:5

organism-modification


PR:000036592 ezrin isoform 1 phosphorylated 5 (human)
hEZR/iso:1/Phos:5
Yes
organism-modification


PR:000044790 ezrin isoform 1 phosphorylated 5 (mouse)
mEZR/iso:1/Phos:5

modification


PR:000003042 ezrin isoform 1 phosphorylated 6
EZR/iso:1/Phos:6

organism-modification


PR:000036625 ezrin isoform 1 phosphorylated 6 (human)
hEZR/iso:1/Phos:6
Yes
modification


PR:000026720 ezrin isoform 1, initiator methionine removed form
EZR/iso:1/InitMet-

modification


PR:000018330 ezrin, initiator methionine removed form
EZR/InitMet-

modification


PR:000026720 ezrin isoform 1, initiator methionine removed form
EZR/iso:1/InitMet-

organism-modification


PR:000047345 ezrin, initiator methionine removed phosphorylated 5 (human)
hEZR/InitMet-/Phos:5

organism-modification


PR:000047346 ezrin, initiator methionine removed phosphorylated 1 (human)
hEZR/InitMet-/Phos:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036589 hEZR/iso:1/Phos:2
UniProtKB:P15311-1, Ser-66, MOD:00046		 enablesGO:0005515 protein binding with PR:000002696 WWOX/iso:1/UnMod PMID:16438931
PR:000036590 hEZR/iso:1/Phos:3
UniProtKB:P15311-1, Tyr-191, MOD:00048		 enablesGO:0005515 protein binding with PR:P00523-1 PMID:15647376
PR:000036592 hEZR/iso:1/Phos:5
UniProtKB:P15311-1, Thr-567, MOD:00047		 acts_upstream_of_or_withinGO:0001771 immunological synapse formation PMID:18025306
GO:0051279 regulation of release of sequestered calcium ion into cytosol PMID:18025306
enablesGO:0005515 protein binding with PR:P43403 70 kDa zeta-chain associated protein (human) PMID:18025306
located_inGO:0001772 immunological synapse PMID:18025306
GO:0045177 apical part of cell PMID:16144865
PR:000036625 hEZR/iso:1/Phos:6
UniProtKB:P15311-1, Tyr-354, MOD:00048|Thr-567, MOD:00047		 enablesGO:0003779 actin binding PMID:18852256
located_inGO:0002102 podosome PMID:18852256
GO:0005886 plasma membrane PMID:18852256