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Protein Ontology report - Toll-like receptor 8
PR:000001159 - http://purl.obolibrary.org/obo/PR_000001159
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001159   
  PRO nameToll-like receptor 8 
  Synonyms
PRO-Short-label: EXACT:TLR8
Gene-based: RELATED:UNQ249/PRO286
Other: EXACT:CD288
  Definition"A Toll-like receptor that is a translation product of the human TLR8 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001096 Toll-like receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1758
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000001159

Toll-like receptor 8

TLR8


"A Toll-like receptor that is a translation product of the human TLR8 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:A1Z9N6

acid labile subunit (fruit fly)

fly-TLR8


"A Toll-like receptor 8 that is encoded in the genome of fruit fly." [PRO:CNA]


organism-gene



PR:A5H300

Toll-like receptor 8 (rat)

rTLR8


"A Toll-like receptor 8 that is encoded in the genome of rat." [OMA:A5H300, PMID:20004021, PRO:CNA]


organism-sequence



PR:A5H300-1

Toll-like receptor 8 isoform 1 (rat)

rTLR8/iso:1


"A Toll-like receptor 8 isoform 1 that is encoded in the genome of rat." [PMID:20004021, PRO:CNA]


Yes
organism-gene



PR:P58682

Toll-like receptor 8 (mouse)

mTLR8


"A Toll-like receptor 8 that is encoded in the genome of mouse." [OMA:P58682, PMID:20004021, PRO:CNA]


organism-sequence



PR:P58682-1

Toll-like receptor 8 isoform 1 (mouse)

mTLR8/iso:1


"A Toll-like receptor 8 isoform 1 that is encoded in the genome of mouse." [PMID:20004021, PRO:CNA]


Yes
organism-gene



PR:Q9NR97

Toll-like receptor 8 (human)

hTLR8


"A Toll-like receptor 8 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9NR97]


organism-sequence



PR:Q9NR97-1

Toll-like receptor 8 isoform 1 (human)

hTLR8/iso:1


"A Toll-like receptor 8 isoform 1 that is encoded in the genome of human." [PMID:20004021, PRO:CNA]


Yes
organism-sequence



PR:Q9NR97-2

Toll-like receptor 8 isoform h2 (human)

hTLR8/iso:h2


"A Toll-like receptor 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR97-2." [PRO:DNx, UniProtKB:Q9NR97]


organism-modification



PR:000049471

Toll-like receptor 8, signal peptide removed form (human)

hTLR8/SigPep-


"A Toll-like receptor 8 (human) that has had the signal peptide removed. UniProtKB:Q9NR97, 27-1041." [PRO:DNx, Reactome:R-HSA-1678918, Reactome:R-HSA-1678947, Reactome:R-HSA-167927, Reactome:R-HSA-1679577]


sequence



PR:000027944

Toll-like receptor 8 isoform 1

TLR8/iso:1


"A Toll-like receptor 8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NR97-1 or a 1:1 ortholog thereof." [PMID:20004021, PRO:CNA]


organism-sequence



PR:A5H300-1

Toll-like receptor 8 isoform 1 (rat)

rTLR8/iso:1


"A Toll-like receptor 8 isoform 1 that is encoded in the genome of rat." [PMID:20004021, PRO:CNA]


Yes
organism-sequence



PR:P58682-1

Toll-like receptor 8 isoform 1 (mouse)

mTLR8/iso:1


"A Toll-like receptor 8 isoform 1 that is encoded in the genome of mouse." [PMID:20004021, PRO:CNA]


Yes
organism-sequence



PR:Q9NR97-1

Toll-like receptor 8 isoform 1 (human)

hTLR8/iso:1


"A Toll-like receptor 8 isoform 1 that is encoded in the genome of human." [PMID:20004021, PRO:CNA]


Yes
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TLR8 forms found in complexes   

TLR8 Component
Complexes
PR:A5H300ZDASHZ1 rTLR8/iso:1 PR:000027953 Toll-like receptor 8 complex (rat)
PR:P58682ZDASHZ1 mTLR8/iso:1 PR:000027952 Toll-like receptor 8 complex (mouse)
PR:Q9NR97ZDASHZ1 hTLR8/iso:1 PR:000027951 Toll-like receptor 8 complex (human)