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Protein Ontology report - interleukin-1 receptor antagonist protein isoform 1
PR:000001228 - http://purl.obolibrary.org/obo/PR_000001228
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001228   
  PRO nameinterleukin-1 receptor antagonist protein isoform 1 
  Synonyms
PRO-Short-label: EXACT:IL1RN/iso:1
Other: EXACT:sIL-1ra
  Definition"An interleukin-1 receptor antagonist protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18510-1 or a 1:1 ortholog thereof." [PMID:2139180, PRO:CNA, PRO:DAN] 
  PRO Categorysequence 
  ParentPR:000001137 interleukin-1 receptor antagonist protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000001228

interleukin-1 receptor antagonist protein isoform 1

IL1RN/iso:1


"An interleukin-1 receptor antagonist protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18510-1 or a 1:1 ortholog thereof." [PMID:2139180, PRO:CNA, PRO:DAN]


organism-sequence



PR:P18510-1

interleukin-1 receptor antagonist protein isoform 1 (human)

hIL1RN/iso:1


"An interleukin-1 receptor antagonist protein isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036601

interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form (human)

hIL1RN/iso:1/SigPep-


"An interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form in human. UniProtKB:P18510-1, 26-177." [PMID:2139180, PRO:CNA]

Yes

organism-sequence



PR:P25085-1

interleukin-1 receptor antagonist protein isoform 1 (mouse)

mIL1RN/iso:1


"An interleukin-1 receptor antagonist protein isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000001271

interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form

IL1RN/iso:1/SigPep-


"An interleukin-1 receptor antagonist protein isoform 1 that has had the signal peptide removed to yield the mature form." [PMID:2139180]


organism-modification



PR:000036601

interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form (human)

hIL1RN/iso:1/SigPep-


"An interleukin-1 receptor antagonist protein isoform 1, signal peptide removed form in human. UniProtKB:P18510-1, 26-177." [PMID:2139180, PRO:CNA]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036601 hIL1RN/iso:1/SigPep-
UniProtKB:P18510-1, 26-177
enablesGO:0045352 interleukin-1 type I receptor antagonist activity PMID:2139180
located_inGO:0005615 extracellular space PMID:2139180