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 |
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family
|
|
PR:000001315 |
frizzled-like G-protein coupled receptor
|
fam:frizzled
|
"A G-protein coupled receptor with core architecture consisting of an Fz domain (Pfam:PF01392), also known as Frizzled CRD (cysteine rich domain), followed by a Frizzled/Smoothened family membrane region (Pfam:PF01534), which includes 7 transmembrane helices, and a cytoplasmic domain containing the motif Lys-Thr-x-x-x-Trp. They generally function as cell-surface receptors for Wnts." [InterPro:IPR015526, PRO:DAN, PRO:WCB]
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gene
|
|
PR:000001453 |
frizzled-10
|
FZD10
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD10 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
|
|
PR:Q8BKG4 |
frizzled-10 (mouse)
|
mFZD10
|
"A frizzled-10 that is encoded in the genome of mouse." [OMA:Q8BKG4, PRO:DNx]
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organism-gene
|
|
PR:Q9PWH2 |
frizzled-10 (chicken)
|
chick-FZD10
|
"A frizzled-10 that is encoded in the genome of chicken." [OMA:Q9PWH2, PRO:DNx]
|
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organism-gene
|
|
PR:Q9ULW2 |
frizzled-10 (human)
|
hFZD10
|
"A frizzled-10 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9ULW2]
|
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| |
organism-modification
|
|
PR:000047470 |
frizzled-10, signal peptide removed form (human)
|
hFZD10/SigPep-
|
"A frizzled-10 (human) that has had the signal peptide removed. UniProtKB:Q9ULW2, 21-581." [PRO:DNx, Reactome:R-HSA-443943]
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gene
|
|
PR:000001454 |
frizzled-4
|
FZD4
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD4 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
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organism-gene
|
|
PR:Q61088 |
frizzled-4 (mouse)
|
mFZD4
|
"A frizzled-4 that is encoded in the genome of mouse." [OMA:Q61088, PRO:DNx]
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| |
organism-sequence
|
|
PR:Q61088-1 |
frizzled-4 isoform 1 (mouse)
|
mFZD4/iso:1
|
"A frizzled-4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
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organism-gene
|
|
PR:Q9IA05 |
frizzled-4 (chicken)
|
chick-FZD4
|
"A frizzled-4 that is encoded in the genome of chicken." [OMA:Q9IA05, PRO:DNx]
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| | | | | | |
| | | |
organism-gene
|
|
PR:Q9QZH0 |
frizzled-4 (rat)
|
rFZD4
|
"A frizzled-4 that is encoded in the genome of rat." [OMA:Q9QZH0, PRO:DNx]
|
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| | | | | | |
| | | |
organism-gene
|
|
PR:Q9ULV1 |
frizzled-4 (human)
|
hFZD4
|
"A frizzled-4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9ULV1]
|
|
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| |
organism-sequence
|
|
PR:Q9ULV1-1 |
frizzled-4 isoform 1 (human)
|
hFZD4/iso:1
|
"A frizzled-4 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
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| |
organism-modification
|
|
PR:000047473 |
frizzled-4, signal peptide removed form (human)
|
hFZD4/SigPep-
|
"A frizzled-4 (human) that has had the signal peptide removed. UniProtKB:Q9ULV1, 37-537." [PRO:DNx, Reactome:R-HSA-443956, Reactome:R-HSA-5138457, Reactome:R-HSA-8869088]
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organism-modification
|
|
PR:000047474 |
frizzled-4, signal peptide removed ubiquitinated form (human)
|
hFZD4/SigPep-/UbiqLys+
|
"A frizzled-4 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9ULV1, 37-537, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641182]
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| | | | | | | | |
| |
organism-modification
|
|
PR:000047474 |
frizzled-4, signal peptide removed ubiquitinated form (human)
|
hFZD4/SigPep-/UbiqLys+
|
"A frizzled-4 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9ULV1, 37-537, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641182]
|
|
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| | | |
sequence
|
|
PR:000044007 |
frizzled-4 isoform 1
|
FZD4/iso:1
|
"A frizzled-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9ULV1-1 or a 1:1 ortholog thereof." [PRO:DNx]
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| |
organism-sequence
|
|
PR:Q61088-1 |
frizzled-4 isoform 1 (mouse)
|
mFZD4/iso:1
|
"A frizzled-4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
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| |
organism-sequence
|
|
PR:Q9ULV1-1 |
frizzled-4 isoform 1 (human)
|
hFZD4/iso:1
|
"A frizzled-4 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
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gene
|
|
PR:000001455 |
frizzled-9
|
FZD9
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD9 gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
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| | | |
organism-gene
|
|
PR:O00144 |
frizzled-9 (human)
|
hFZD9
|
"A frizzled-9 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O00144]
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|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047481 |
frizzled-9, signal peptide removed form (human)
|
hFZD9/SigPep-
|
"A frizzled-9 (human) that has had the signal peptide removed. UniProtKB:O00144, 23-591." [PRO:DNx, Reactome:R-HSA-443946]
|
|
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| | | | | | |
| | | |
organism-gene
|
|
PR:Q8K4C8 |
frizzled-9 (rat)
|
rFZD9
|
"A frizzled-9 that is encoded in the genome of rat." [OMA:Q8K4C8, PRO:DNx]
|
|
|
|
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|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9R216 |
frizzled-9 (mouse)
|
mFZD9
|
"A frizzled-9 that is encoded in the genome of mouse." [OMA:Q9R216, PRO:DNx]
|
|
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| | | | |
| | | | | |
gene
|
|
PR:000007718 |
frizzled-1
|
FZD1
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD1 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
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| | | | | | |
| | | |
organism-gene
|
|
PR:O57328 |
frizzled-1 (chicken)
|
chick-FZD1
|
"A frizzled-1 that is encoded in the genome of chicken." [OMA:O57328, PRO:DNx]
|
|
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| | | | | | |
| | | |
organism-gene
|
|
PR:O70421 |
frizzled-1 (mouse)
|
mFZD1
|
"A frizzled-1 that is encoded in the genome of mouse." [OMA:O70421, PRO:DNx]
|
|
|
|
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| | | | | | |
| | | |
organism-gene
|
|
PR:Q08463 |
frizzled-1 (rat)
|
rFZD1
|
"A frizzled-1 that is encoded in the genome of rat." [OMA:Q08463, PRO:DNx]
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| | | | | | |
| | | |
organism-gene
|
|
PR:Q9UP38 |
frizzled-1 (human)
|
hFZD1
|
"A frizzled-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UP38]
|
|
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|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047469 |
frizzled-1, signal peptide removed form (human)
|
hFZD1/SigPep-
|
"A frizzled-1 (human) that has had the signal peptide removed. UniProtKB:Q9UP38, 70-647." [PRO:DNx, Reactome:R-HSA-205974]
|
|
|
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| | | | | | | | |
| |
organism-modification
|
|
PR:000058343 |
frizzled-1 O-glycosylated 1 (human)
|
hFZD1/OGlyco:1
|
"A frizzled-1 (human) that has been O-glycosylated at the residue equivalent to Ser-241 of the amino acid sequence represented by UniProtKB:Q9UP38-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9UP38-1, Ser-241, MOD:00002~GNO:G43417UB." [GlyGen:Q9UP38-1, PMID:30459171, PRO:DNx]
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|
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| | | | | | | | |
| |
organism-modification
|
|
PR:000058344 |
frizzled-1 O-glycosylated 2 (human)
|
hFZD1/OGlyco:2
|
"A frizzled-1 (human) that has been O-glycosylated at the residue equivalent to Thr-239 of the amino acid sequence represented by UniProtKB:Q9UP38-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q9UP38-1, Thr-239, MOD:00005~GNO:G53434XO." [GlyGen:Q9UP38-1, PMID:30459171, PRO:DNx]
|
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| | | | | |
gene
|
|
PR:000007719 |
frizzled-2
|
FZD2
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD2 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
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|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q08464 |
frizzled-2 (rat)
|
rFZD2
|
"A frizzled-2 that is encoded in the genome of rat." [OMA:Q08464, PRO:DNx]
|
|
|
|
|
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|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q14332 |
frizzled-2 (human)
|
hFZD2
|
"A frizzled-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14332]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047471 |
frizzled-2, signal peptide removed form (human)
|
hFZD2/SigPep-
|
"A frizzled-2 (human) that has had the signal peptide removed. UniProtKB:Q14332, 24-565." [PRO:DNx, Reactome:R-HSA-443945, Reactome:R-HSA-5140723]
|
|
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|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000057124 |
frizzled-2 O-glycosylated 1 (human)
|
hFZD2/OGlyco:1
|
"A frizzled-2 (human) that has been O-glycosylated at the residue equivalent to Thr-165 of the amino acid sequence represented by UniProtKB:Q14332-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q14332-1, Thr-165, MOD:00005~GNO:G53434XO." [GlyGen:Q14332-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000057125 |
frizzled-2 O-glycosylated 2 (human)
|
hFZD2/OGlyco:2
|
"A frizzled-2 (human) that has been O-glycosylated at the residue equivalent to Thr-179 of the amino acid sequence represented by UniProtKB:Q14332-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q14332-1, Thr-179, MOD:00005~GNO:G43417UB." [GlyGen:Q14332-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9JIP6 |
frizzled-2 (mouse)
|
mFZD2
|
"A frizzled-2 that is encoded in the genome of mouse." [OMA:Q9JIP6, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000007720 |
frizzled-3
|
FZD3
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD3 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q61086 |
frizzled-3 (mouse)
|
mFZD3
|
"A frizzled-3 that is encoded in the genome of mouse." [OMA:Q61086, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q61086-1 |
frizzled-3 isoform 1 (mouse)
|
mFZD3/iso:1
|
"A frizzled-3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000076795 |
frizzled-3 cysteinylated 1 (mouse)
|
mFZD3/Cyst:1
|
"A frizzled-3 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-361 of the amino acid sequence represented by UniProtKB:Q61086. UniProtKB:Q61086, Cys-361, MOD:00765." [IEDB_epitope:2107498, PRO:DNx]
|
|
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|
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|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9NPG1 |
frizzled-3 (human)
|
hFZD3
|
"A frizzled-3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NPG1]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q9NPG1-1 |
frizzled-3 isoform Long (human)
|
hFZD3/iso:Long
|
"A frizzled-3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q9NPG1-2 |
frizzled-3 isoform Short (human)
|
hFZD3/iso:Short
|
"A frizzled-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NPG1-2." [PRO:DNx, UniProtKB:Q9NPG1]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047472 |
frizzled-3, signal peptide removed form (human)
|
hFZD3/SigPep-
|
"A frizzled-3 (human) that has had the signal peptide removed. UniProtKB:Q9NPG1, 23-666." [PRO:DNx, Reactome:R-HSA-443948]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000043476 |
frizzled-3 isoform 1
|
FZD3/iso:1
|
"A frizzled-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NPG1-1 or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q61086-1 |
frizzled-3 isoform 1 (mouse)
|
mFZD3/iso:1
|
"A frizzled-3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q9NPG1-1 |
frizzled-3 isoform Long (human)
|
hFZD3/iso:Long
|
"A frizzled-3 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000019950 |
frizzled-3, signal peptide removed form
|
FZD3/SigPep-
|
"A frizzled-3 that has had the signal peptide removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047472 |
frizzled-3, signal peptide removed form (human)
|
hFZD3/SigPep-
|
"A frizzled-3 (human) that has had the signal peptide removed. UniProtKB:Q9NPG1, 23-666." [PRO:DNx, Reactome:R-HSA-443948]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000007721 |
frizzled-5
|
FZD5
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD5 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q13467 |
frizzled-5 (human)
|
hFZD5
|
"A frizzled-5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13467]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q13467-1 |
frizzled-5 isoform 1 (human)
|
hFZD5/iso:1
|
"A frizzled-5 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047475 |
frizzled-5, signal peptide removed form (human)
|
hFZD5/SigPep-
|
"A frizzled-5 (human) that has had the signal peptide removed. UniProtKB:Q13467, 27-585." [PRO:DNx, Reactome:R-HSA-443952, Reactome:R-HSA-5140725, Reactome:R-HSA-5368467]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000047476 |
frizzled-5, signal peptide removed ubiquitinated form (human)
|
hFZD5/SigPep-/UbiqLys+
|
"A frizzled-5 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q13467, 27-585, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641190]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047476 |
frizzled-5, signal peptide removed ubiquitinated form (human)
|
hFZD5/SigPep-/UbiqLys+
|
"A frizzled-5 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q13467, 27-585, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641190]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000057033 |
frizzled-5 O-glycosylated 1 (human)
|
hFZD5/OGlyco:1
|
"A frizzled-5 (human) that has been O-glycosylated at the residue equivalent to Thr-168 of the amino acid sequence represented by UniProtKB:Q13467-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q13467-1, Thr-168, MOD:00005~GNO:G43417UB." [GlyGen:Q13467-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q1ZXI9 |
frizzled and smoothened-like protein O (Dictyostelium discoideum)
|
Dicty-FZD5
|
"A frizzled-5 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q1ZXI9, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q8CHL0 |
frizzled-5 (rat)
|
rFZD5
|
"A frizzled-5 that is encoded in the genome of rat." [OMA:Q8CHL0, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q8CHL0-1 |
frizzled-5 isoform 1 (rat)
|
rFZD5/iso:1
|
"A frizzled-5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9EQD0 |
frizzled-5 (mouse)
|
mFZD5
|
"A frizzled-5 that is encoded in the genome of mouse." [OMA:Q9EQD0, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q9EQD0-1 |
frizzled-5 isoform 1 (mouse)
|
mFZD5/iso:1
|
"A frizzled-5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000040435 |
frizzled-5 isoform 1
|
FZD5/iso:1
|
"A frizzled-5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13467-1 or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q13467-1 |
frizzled-5 isoform 1 (human)
|
hFZD5/iso:1
|
"A frizzled-5 isoform 1 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q8CHL0-1 |
frizzled-5 isoform 1 (rat)
|
rFZD5/iso:1
|
"A frizzled-5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q9EQD0-1 |
frizzled-5 isoform 1 (mouse)
|
mFZD5/iso:1
|
"A frizzled-5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000007722 |
frizzled-6
|
FZD6
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD6 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:O60353 |
frizzled-6 (human)
|
hFZD6
|
"A frizzled-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60353]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:O60353-1 |
frizzled-6 isoform h1 (human)
|
hFZD6/iso:h1
|
"A frizzled-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60353-1." [PRO:DNx, UniProtKB:O60353]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:O60353-2 |
frizzled-6 isoform h2 (human)
|
hFZD6/iso:h2
|
"A frizzled-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60353-2." [PRO:DNx, UniProtKB:O60353]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047477 |
frizzled-6, signal peptide removed ubiquitinated form (human)
|
hFZD6/SigPep-/UbiqLys+
|
"A frizzled-6 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:O60353, 19-706, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641189]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050771 |
frizzled-6 N-glycosylated 1 (human)
|
hFZD6/NGlyco:1
|
"A frizzled-6 (human) that has been N-glycosylated at the residue equivalent to Asn-38 of the amino acid sequence represented by UniProtKB:O60353-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:O60353-1, Asn-38, MOD:00160~GNO:G27947YN." [GlyGen:O60353-1, PMID:29671580, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050772 |
frizzled-6 N-glycosylated 2 (human)
|
hFZD6/NGlyco:2
|
"A frizzled-6 (human) that has been N-glycosylated at the residue equivalent to Asn-38 of the amino acid sequence represented by UniProtKB:O60353-1, in which the glycan composition is represented by GlyTouCan:G99679NM. Example: UniProtKB:O60353-1, Asn-38, MOD:00160~GNO:G99679NM." [GlyGen:O60353-1, PMID:29671580, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050773 |
frizzled-6 O-glycosylated 1 (human)
|
hFZD6/OGlyco:1
|
"A frizzled-6 (human) that has been O-glycosylated at the residue equivalent to Thr-136 of the amino acid sequence represented by UniProtKB:O60353-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60353-1, Thr-136, MOD:00005~GNO:G43417UB." [GlyGen:O60353-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050774 |
frizzled-6 O-glycosylated 2 (human)
|
hFZD6/OGlyco:2
|
"A frizzled-6 (human) that has been O-glycosylated at the residue equivalent to Thr-141 of the amino acid sequence represented by UniProtKB:O60353-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60353-1, Thr-141, MOD:00005~GNO:G43417UB." [GlyGen:O60353-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000063743 |
frizzled-6, signal peptide removed form (human)
|
hFZD6/SigPep-
|
"A frizzled-6 (human) that has had the signal peptide removed. Example: UniProtKB:O60353-1, 19-706." [PRO:DNx, Reactome:R-HSA-443950]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000066533 |
frizzled-6 cysteinylated 1 (human)
|
hFZD6/Cyst:1
|
"A frizzled-6 (human) that has been cysteinylated on the residue at the position equivalent to Cys-24 of the amino acid sequence represented by UniProtKB:O60353-1. Example: UniProtKB:O60353-1, Cys-24, MOD:00765." [IEDB_epitope:637002, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000080579 |
frizzled-6 deaminated 1 (human)
|
hFZD6/Deam:1
|
"A frizzled-6 (human) that has been deaminated on the residue at the position equivalent to Asn-66 of the amino acid sequence represented by UniProtKB:O60353-1. Example: UniProtKB:O60353-1, Asn-66, MOD:00684." [IEDB_epitope:1762572, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q61089 |
frizzled-6 (mouse)
|
mFZD6
|
"A frizzled-6 that is encoded in the genome of mouse." [OMA:Q61089, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000007723 |
frizzled-7
|
FZD7
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD7 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:O57329 |
frizzled-7 (chicken)
|
chick-FZD7
|
"A frizzled-7 that is encoded in the genome of chicken." [OMA:O57329, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:O75084 |
frizzled-7 (human)
|
hFZD7
|
"A frizzled-7 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75084]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047478 |
frizzled-7, signal peptide removed form (human)
|
hFZD7/SigPep-
|
"A frizzled-7 (human) that has had the signal peptide removed. UniProtKB:O75084, 33-574." [PRO:DNx, Reactome:R-HSA-517394]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050815 |
frizzled-7 O-glycosylated 1 (human)
|
hFZD7/OGlyco:1
|
"A frizzled-7 (human) that has been O-glycosylated at the residue equivalent to Thr-191 of the amino acid sequence represented by UniProtKB:O75084-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O75084-1, Thr-191, MOD:00005~GNO:G43417UB." [GlyGen:O75084-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q61090 |
frizzled-7 (mouse)
|
mFZD7
|
"A frizzled-7 that is encoded in the genome of mouse." [OMA:Q61090, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000068087 |
frizzled-7 cysteinylated 1 (mouse)
|
mFZD7/Cyst:1
|
"A frizzled-7 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-110 of the amino acid sequence represented by UniProtKB:Q61090. UniProtKB:Q61090, Cys-110, MOD:00765." [IEDB_epitope:2102642, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000007724 |
frizzled-8
|
FZD8
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human FZD8 gene or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q498S8 |
frizzled-8 (rat)
|
rFZD8
|
"A frizzled-8 that is encoded in the genome of rat." [OMA:Q498S8, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q61091 |
frizzled-8 (mouse)
|
mFZD8
|
"A frizzled-8 that is encoded in the genome of mouse." [OMA:Q61091, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9H461 |
frizzled-8 (human)
|
hFZD8
|
"A frizzled-8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H461]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047479 |
frizzled-8, signal peptide removed form (human)
|
hFZD8/SigPep-
|
"A frizzled-8 (human) that has had the signal peptide removed. UniProtKB:Q9H461, 28-694." [PRO:DNx, Reactome:R-HSA-443947]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000047480 |
frizzled-8, signal peptide removed ubiquitinated form (human)
|
hFZD8/SigPep-/UbiqLys+
|
"A frizzled-8 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9H461, 28-694, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641183]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000047480 |
frizzled-8, signal peptide removed ubiquitinated form (human)
|
hFZD8/SigPep-/UbiqLys+
|
"A frizzled-8 (human) that has had the signal peptide removed and that includes at least one ubiquitinated lysine. UniProtKB:Q9H461, 28-694, MOD:01148." [PRO:DNx, Reactome:R-HSA-4641183]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000015288 |
protein smoothened
|
SMO
|
"A frizzled-like G-protein coupled receptor that is a translation product of the human SMO gene or a 1:1 ortholog thereof." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P56726 |
protein smoothened (mouse)
|
mSMO
|
"A protein smoothened that is encoded in the genome of mouse." [OMA:P56726, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P56726-1 |
protein smoothened isoform 1 (mouse)
|
mSMO/iso:1
|
"A protein smoothened isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P91682 |
protein smoothened (fruit fly)
|
fly-SMO
|
"A protein smoothened that is encoded in the genome of fruit fly." [PANTHER:PTHR11309:SF35, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P97698 |
protein smoothened (rat)
|
rSMO
|
"A protein smoothened that is encoded in the genome of rat." [OMA:P97698, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P97698-1 |
protein smoothened isoform 1 (rat)
|
rSMO/iso:1
|
"A protein smoothened isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q5RH73 |
protein smoothened (zebrafish)
|
z-SMO
|
"A protein smoothened that is encoded in the genome of zebrafish." [OMA:Q5RH73, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q99835 |
protein smoothened (human)
|
hSMO
|
"A protein smoothened that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99835]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000049297 |
protein smoothened, signal peptide removed form (human)
|
hSMO/SigPep-
|
"A protein smoothened (human) that has had the signal peptide removed. UniProtKB:Q99835, 28-787." [PRO:DNx, Reactome:R-HSA-445121, Reactome:R-HSA-5610419, Reactome:R-HSA-5610422, Reactome:R-HSA-5624094]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000049298 |
protein smoothened, signal peptide removed phosphorylated 1 (human)
|
hSMO/SigPep-/Phos:1
|
"A protein smoothened (human) that has had the signal peptide removed and has been post-translationally modified to include phosphoserine at positions 588, 590 and 595, and phosphothreonine at position 593 of the amino acid sequence represented by UniProtKB:Q99835. UniProtKB:Q99835, 28-787, Ser-588/Ser-590/Ser-595, MOD:00046|Thr-593, MOD:00047." [PRO:DNx, Reactome:R-HSA-5632525]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000049299 |
protein smoothened, signal peptide removed phosphorylated 2 (human)
|
hSMO/SigPep-/Phos:2
|
"A protein smoothened (human) that has had the signal peptide removed and has been post-translationally modified to include phosphoserine at positions 588, 590, 595, 611, 615 and 616, and phosphothreonine at position 593 of the amino acid sequence represented by UniProtKB:Q99835. UniProtKB:Q99835, 28-787, Ser-588/Ser-590/Ser-595/Ser-611/Ser-615/Ser-616, MOD:00046|Thr-593, MOD:00047." [PRO:DNx, Reactome:R-HSA-5632528]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000057979 |
protein smoothened N-glycosylated 1 (human)
|
hSMO/NGlyco:1
|
"A protein smoothened (human) that has been N-glycosylated at the residue equivalent to Asn-35 of the amino acid sequence represented by UniProtKB:Q99835-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:Q99835-1, Asn-35, MOD:00160~GNO:G08293MJ." [GlyGen:Q99835-1, PMID:29671580, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000057980 |
protein smoothened O-glycosylated 1 (human)
|
hSMO/OGlyco:1
|
"A protein smoothened (human) that has been O-glycosylated at the residue equivalent to Thr-500 of the amino acid sequence represented by UniProtKB:Q99835-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q99835-1, Thr-500, MOD:00005~GNO:G29068FM." [GlyGen:Q99835-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000057981 |
protein smoothened O-glycosylated 2 (human)
|
hSMO/OGlyco:2
|
"A protein smoothened (human) that has been O-glycosylated at the residue equivalent to Thr-55 of the amino acid sequence represented by UniProtKB:Q99835-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q99835-1, Thr-55, MOD:00005~GNO:G43417UB." [GlyGen:Q99835-1, PMID:30459171, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000039833 |
protein smoothened isoform 1
|
SMO/iso:1
|
"A protein smoothened that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56726-1 or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P56726-1 |
protein smoothened isoform 1 (mouse)
|
mSMO/iso:1
|
"A protein smoothened isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P97698-1 |
protein smoothened isoform 1 (rat)
|
rSMO/iso:1
|
"A protein smoothened isoform 1 that is encoded in the genome of rat." [PRO:DNx]
|
|
|
|
|
