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Protein Ontology report - nuclear factor NF-kappa-B p105 subunit
PR:000001754 - http://purl.obolibrary.org/obo/PR_000001754
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001754   
  PRO namenuclear factor NF-kappa-B p105 subunit 
  Synonyms
PRO-Short-label: EXACT:NFKB1
Other: EXACT:DNA-binding factor KBF1 | EBP-1 | NF-kappa-B1 p84/NF-kappa-B1 p98 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  Definition"A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB1 gene or a 1:1 ortholog thereof. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis." [PMID:15485931, PRO:JAN] 
  PRO Categorygene 
  ParentPR:000001753 transcription factor NF-kappa-B subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence3                                                  Organism-Sequence 15                                        
         Modification5                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
gene



PR:000001754 nuclear factor NF-kappa-B p105 subunit

NFKB1


organism-gene



PR:P19838 nuclear factor NF-kappa-B p105 subunit (human)

hNFKB1


Yes
organism-sequence



PR:P19838-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (human)

hNFKB1/iso:1


organism-sequence



PR:P19838-2 nuclear factor NF-kappa-B p105 subunit isoform 2 (human)

hNFKB1/iso:2


organism-sequence



PR:P19838-3 nuclear factor NF-kappa-B p105 subunit isoform h3 (human)

hNFKB1/iso:h3


organism-modification



PR:000035834 nuclear factor NF-kappa-B p50 subunit (human)

hNFKBp50

Yes

Yes
organism-modification



PR:000045706 nuclear factor NF-kappa-B p105 subunit phosphorylated 1 (human)

hNFKB1/Phos:1


organism-modification



PR:000048595 nuclear factor NF-kappa-B p105 subunit phosphorylated 2 (human)

hNFKB1/Phos:2


organism-modification



PR:000064699 nuclear factor NF-kappa-B p105 subunit phosphorylated and ubiquitinated 1 (human)

hNFKB1/PhosUbiq:1


organism-modification



PR:000072853 nuclear factor NF-kappa-B p105 subunit deaminated 1 (human)

hNFKB1/Deam:1


organism-modification



PR:000075491 nuclear factor NF-kappa-B p105 subunit cysteinylated 1 (human)

hNFKB1/Cyst:1


organism-modification



PR:000080523 nuclear factor NF-kappa-B p105 subunit deaminated 2 (human)

hNFKB1/Deam:2


organism-modification



PR:000083954 nuclear factor NF-kappa-B p105 subunit deaminated 3 (human)

hNFKB1/Deam:3


organism-gene



PR:P25799 nuclear factor NF-kappa-B p105 subunit (mouse)

mNFKB1


organism-sequence



PR:P25799-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (mouse)

mNFKB1/iso:1


organism-modification



PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse)

mNFKBp50


Yes
organism-sequence



PR:P25799-2 nuclear factor NF-kappa-B p105 subunit isoform m2 (mouse)

mNFKB1/iso:m2


organism-sequence



PR:P25799-3 nuclear factor NF-kappa-B p105 subunit isoform m3 (mouse)

mNFKB1/iso:m3


organism-sequence



PR:P25799-4 nuclear factor NF-kappa-B p105 subunit isoform m4 (mouse)

mNFKB1/iso:m4


organism-sequence



PR:P25799-5 nuclear factor NF-kappa-B p105 subunit isoform m5 (mouse)

mNFKB1/iso:m5


organism-sequence



PR:P25799-6 nuclear factor NF-kappa-B p105 subunit isoform m6 (mouse)

mNFKB1/iso:m6


organism-sequence



PR:P25799-7 nuclear factor NF-kappa-B p105 subunit isoform m7 (mouse)

mNFKB1/iso:m7


organism-gene



PR:Q04861 nuclear factor NF-kappa-B p105 subunit (chicken)

chick-NFKB1


organism-sequence



PR:Q04861-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (chicken)

chick-NFKB1/iso:1


organism-sequence



PR:Q04861-2 nuclear factor NF-kappa-B p105 subunit isoform 2 (chicken)

chick-NFKB1/iso:2


organism-sequence



PR:Q04861-3 nuclear factor NF-kappa-B p105 subunit isoform 3 (chicken)

chick-NFKB1/iso:3


organism-gene



PR:Q63369 nuclear factor NF-kappa-B p105 subunit (rat)

rNFKB1


organism-gene



PR:Q94527 nuclear factor NF-kappa-B p110 subunit (fruit fly)

fly-NFKB1


organism-sequence



PR:Q94527-1 nuclear factor NF-kappa-B p110 subunit isoform Major (fruit fly)

fly-NFKB1/iso:Major


organism-sequence



PR:Q94527-2 nuclear factor NF-kappa-B p110 subunit isoform Maternal (fruit fly)

fly-NFKB1/iso:Maternal


sequence



PR:000001755 nuclear factor NF-kappa-B p105 subunit isoform 1

NFKB1/iso:1


organism-sequence



PR:P25799-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (mouse)

mNFKB1/iso:1


organism-modification



PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse)

mNFKBp50


Yes
modification



PR:000001757 nuclear factor NF-kappa-B p50 subunit

NFKBp50


organism-modification



PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse)

mNFKBp50


Yes
organism-modification



PR:000035834 nuclear factor NF-kappa-B p50 subunit (human)

hNFKBp50

Yes

Yes
sequence



PR:000001758 nuclear factor NF-kappa-B p105 subunit isoform 2

NFKB1/iso:2


organism-sequence



PR:P19838-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (human)

hNFKB1/iso:1


modification



PR:000001759 nuclear factor NF-kappa-B p105 subunit isoform 2 phosphorylated form

NFKB1/iso:2/PhosRes+


modification



PR:000001760 nuclear factor NF-kappa-B p105 subunit isoform 2 phosphorylated 1

NFKB1/iso:2/Phos:1


modification



PR:000001762 nuclear factor NF-kappa-B p105 subunit isoform 2 phosphorylated 2

NFKB1/iso:2/Phos:2


sequence



PR:000001761 nuclear factor NF-kappa-B p105 subunit isoform 3

NFKB1/iso:3


organism-sequence



PR:P19838-2 nuclear factor NF-kappa-B p105 subunit isoform 2 (human)

hNFKB1/iso:2


modification



PR:000018519 nuclear factor NF-kappa-B p105 subunit proteolytic cleavage product

NFKB1/ClvPrd


modification



PR:000001757 nuclear factor NF-kappa-B p50 subunit

NFKBp50


organism-modification



PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse)

mNFKBp50


Yes
organism-modification



PR:000035834 nuclear factor NF-kappa-B p50 subunit (human)

hNFKBp50

Yes

Yes
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NFKB1 forms found in complexes   

NFKB1 Component
Complexes
PR:000028540 mNFKBp50 PR:000028542 NF-kappaB p50/p65 complex (mouse)
PR:000035834 hNFKBp50 PR:000035835 NF-kappaB p50/p65 complex (human)
PR:P19838 hNFKB1 PR:000028444 NFKB p105:TPL2:ABIN2 (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0034142 toll-like receptor 4 signaling pathwayPR:000035834 hNFKBp50 Reactome:REACT_6894