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Protein Ontology report - prominin
PR:000001785 - http://purl.obolibrary.org/obo/PR_000001785
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001785   
  PRO nameprominin 
  Definition"A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain." [InterPro:IPR008795, PMID:11467842
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 8                                        
         Sequence6                                                  Organism-Sequence 19                                        
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF017831
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
family



PR:000001785

prominin

IRAK3


"A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain." [InterPro:IPR008795, PMID:11467842]


gene



PR:000001786

prominin-1

PROM1


"A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:E1C9E2

uncharacterized protein, PROM1 translation product (chicken)

chick-PROM1


"A prominin-1 that is encoded in the genome of chicken." [OMA:E1C9E2, PRO:CNA]


organism-gene



PR:O43490

prominin-1 (human)

hPROM1


"A prominin-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O43490]


organism-sequence



PR:O43490-1

prominin-1 isoform h1 (human)

hPROM1/iso:h1


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-1." [PRO:DNx, UniProtKB:O43490]


organism-sequence



PR:O43490-2

prominin-1 isoform h2 (human)

hPROM1/iso:h2


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-2." [PRO:DNx, UniProtKB:O43490]


organism-sequence



PR:O43490-3

prominin-1 isoform h3 (human)

hPROM1/iso:h3


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-3." [PRO:DNx, UniProtKB:O43490]


organism-sequence



PR:O43490-4

prominin-1 isoform h4 (human)

hPROM1/iso:h4


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-4." [PRO:DNx, UniProtKB:O43490]


organism-sequence



PR:O43490-5

prominin-1 isoform h5 (human)

hPROM1/iso:h5


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-5." [PRO:DNx, UniProtKB:O43490]


organism-sequence



PR:O43490-6

prominin-1 isoform h6 (human)

hPROM1/iso:h6


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-6." [PRO:DNx, UniProtKB:O43490]


organism-sequence



PR:O43490-7

prominin-1 isoform h7 (human)

hPROM1/iso:h7


"A prominin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43490-7." [PRO:DNx, UniProtKB:O43490]


organism-gene



PR:O54990

prominin-1 (mouse)

mPROM1


"A prominin-1 that is encoded in the genome of mouse." [OMA:O54990, PRO:DNx]


organism-sequence



PR:O54990-1

prominin-1 isoform 1 (mouse)

mPROM1/iso:1


"A prominin-1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:O54990-2

prominin-1 isoform m2 (mouse)

mPROM1/iso:m2


"A prominin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54990-2." [PRO:DNx, UniProtKB:O54990]


organism-sequence



PR:O54990-3

prominin-1 isoform 3 (mouse)

mPROM1/iso:3


"A prominin-1 isoform 3 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:O54990-4

prominin-1 isoform 4 (mouse)

mPROM1/iso:4


"A prominin-1 isoform 4 that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:O54990-5

prominin-1 isoform 5 (mouse)

mPROM1/iso:5


"A prominin-1 isoform 5 that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:O54990-6

prominin-1 isoform 6 (mouse)

mPROM1/iso:6


"A prominin-1 isoform 6 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-gene



PR:P82295

prominin-like protein (fruit fly)

fly-PROM1


"A prominin-1 that is encoded in the genome of fruit fly." [PRO:CNA]


organism-gene



PR:Q9W735

prominin-1-A (zebrafish)

z-PROM1


"A prominin-1 that is encoded in the genome of zebrafish." [PRO:CNA]


sequence



PR:000001787

prominin-1 isoform 1

PROM1/iso:1


"A prominin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54990-1 or a 1:1 ortholog thereof." [PRO:HJD]


organism-sequence



PR:O54990-1

prominin-1 isoform 1 (mouse)

mPROM1/iso:1


"A prominin-1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]


sequence



PR:000001788

prominin-1 isoform 3

PROM1/iso:3


"A prominin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54990-3 or a 1:1 ortholog thereof." [PMID:15316084, PRO:HJD]


organism-sequence



PR:O54990-3

prominin-1 isoform 3 (mouse)

mPROM1/iso:3


"A prominin-1 isoform 3 that is encoded in the genome of mouse." [PRO:HJD]

Yes

modification



PR:000001793

prominin-1 isoform 3 glycosylated form

PROM1/iso:3/GlycoRes+


"A prominin-1 isoform 3 that includes at least one glycosylated residue." [PRO:HJD]


sequence



PR:000001789

prominin-1 isoform 4

PROM1/iso:4


"A prominin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54990-4 or a 1:1 ortholog thereof." [PMID:15316084, PRO:HJD]


organism-sequence



PR:O54990-4

prominin-1 isoform 4 (mouse)

mPROM1/iso:4


"A prominin-1 isoform 4 that is encoded in the genome of mouse." [PRO:HJD]


sequence



PR:000001790

prominin-1 isoform 5

PROM1/iso:5


"A prominin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54990-5 or a 1:1 ortholog thereof." [PMID:15316084, PRO:HJD]


organism-sequence



PR:O54990-5

prominin-1 isoform 5 (mouse)

mPROM1/iso:5


"A prominin-1 isoform 5 that is encoded in the genome of mouse." [PRO:HJD]


sequence



PR:000001791

prominin-1 isoform 6

PROM1/iso:6


"A prominin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54990-6 or a 1:1 ortholog thereof." [PMID:15316084, PRO:HJD]


organism-sequence



PR:O54990-6

prominin-1 isoform 6 (mouse)

mPROM1/iso:6


"A prominin-1 isoform 6 that is encoded in the genome of mouse." [PRO:HJD]

Yes

modification



PR:000001792

prominin-1 isoform 6 glycosylated form

PROM1/iso:6/GlycoRes+


"A prominin-1 isoform 6 that includes at least one glycosylated residue." [PRO:HJD]


gene



PR:000013267

prominin-2

PROM2


"A prominin that is a translation product of the human PROM2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q3UUY6

prominin-2 (mouse)

mPROM2


"A prominin-2 that is encoded in the genome of mouse." [OMA:Q3UUY6, PRO:DNx]


organism-sequence



PR:Q3UUY6-1

prominin-2 isoform m1 (mouse)

mPROM2/iso:m1


"A prominin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UUY6-1." [PRO:DNx, UniProtKB:Q3UUY6]


organism-sequence



PR:Q3UUY6-2

prominin-2 isoform m2 (mouse)

mPROM2/iso:m2


"A prominin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UUY6-2." [PRO:DNx, UniProtKB:Q3UUY6]


organism-gene



PR:Q8CJ52

prominin-2 (rat)

rPROM2


"A prominin-2 that is encoded in the genome of rat." [OMA:Q8CJ52, PRO:DNx]


organism-sequence



PR:Q8CJ52-1

prominin-2 isoform 1 (rat)

rPROM2/iso:1


"A prominin-2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q8N271

prominin-2 (human)

hPROM2


"A prominin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N271]


organism-sequence



PR:Q8N271-1

prominin-2 isoform 1 (human)

hPROM2/iso:1


"A prominin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q8N271-2

prominin-2 isoform h2 (human)

hPROM2/iso:h2


"A prominin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N271-2." [PRO:DNx, UniProtKB:Q8N271]


organism-sequence



PR:Q8N271-3

prominin-2 isoform h3 (human)

hPROM2/iso:h3


"A prominin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N271-3." [PRO:DNx, UniProtKB:Q8N271]


organism-modification



PR:000071977

prominin-2 deaminated 1 (human)

hPROM2/Deam:1


"A prominin-2 (human) that has been deaminated on the residue at the position equivalent to Gln-257 of the amino acid sequence represented by UniProtKB:Q8N271-1. Example: UniProtKB:Q8N271-1, Gln-257, MOD:00685." [IEDB_epitope:1370644, PRO:DNx]


sequence



PR:000041813

prominin-2 isoform 1

PROM2/iso:1


"A prominin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8N271-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:Q8CJ52-1

prominin-2 isoform 1 (rat)

rPROM2/iso:1


"A prominin-2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q8N271-1

prominin-2 isoform 1 (human)

hPROM2/iso:1


"A prominin-2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O54990-3 mPROM1/iso:3 located_inGO:0009986 cell surface PMID:15316084
GO:0042995 cell projection PMID:15316084
PR:O54990-6 mPROM1/iso:6 located_inGO:0009986 cell surface PMID:15316084
GO:0042995 cell projection PMID:15316084