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Protein Ontology report - interleukin-6 receptor subunit alpha isoform 1
PR:000001794 -
http://purl.obolibrary.org/obo/PR_000001794
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000001794
PRO name
interleukin-6 receptor subunit alpha isoform 1
Synonyms
PRO-Short-label
:
EXACT:
IL6R/iso:1
Definition
"An interleukin-6 receptor subunit alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P22272-1
or a 1:1 ortholog thereof." [PRO:HJD]
PRO Category
sequence
Parent
PR:000001394
interleukin-6 receptor subunit alpha
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
2
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
sequence
PR:000001794
interleukin-6 receptor subunit alpha isoform 1
IL6R/iso:1
organism-sequence
PR:P22272-1
interleukin-6 receptor subunit alpha isoform 1 (mouse)
mIL6R/iso:1
Yes
organism-modification
PR:000044514
interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
modification
PR:000001798
interleukin-6 receptor subunit alpha isoform 1 soluble form
IL6R/iso:1/Clv:soluble
organism-modification
PR:000044514
interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
modification
PR:000026630
interleukin-6 receptor subunit alpha isoform 1, signal peptide removed form
IL6R/iso:1/SigPep-
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0070102
interleukin-6-mediated signaling pathway
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
PR:P22272-1
mIL6R/iso:1
MGI_ref:50330;
PMID:1312474
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004915
interleukin-6 receptor activity
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
PR:P22272-1
mIL6R/iso:1
MGI_ref:50330;
PMID:1312474
GO:0019981
interleukin-6 binding
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
PR:P22272-1
mIL6R/iso:1
MGI_ref:50330;
PMID:1312474
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615
extracellular space
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
GO:0009986
cell surface
PR:P22272-1
mIL6R/iso:1
MGI_ref:50330;
PMID:1312474
