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Protein Ontology report - interleukin-6 receptor subunit alpha isoform 1 soluble form
PR:000001798 -
http://purl.obolibrary.org/obo/PR_000001798
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000001798
PRO name
interleukin-6 receptor subunit alpha isoform 1 soluble form
Synonyms
PRO-Short-label
:
EXACT:
IL6R/iso:1/Clv:soluble
Other
:
EXACT:
sIL-6R
Definition
"An interleukin-6 receptor subunit alpha isoform 1 that has been post-translationally cleaved to release the extracellular domain into the extracellular space." [
PMID:8477802
, PRO:HJD]
PRO Category
modification
Parent
PR:000001794
interleukin-6 receptor subunit alpha isoform 1
PR:000025429
interleukin-6 receptor subunit alpha proteolytic cleavage product
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000001798
interleukin-6 receptor subunit alpha isoform 1 soluble form
IL6R/iso:1/Clv:soluble
organism-modification
PR:000044514
interleukin-6 receptor subunit alpha isoform 1 soluble form (mouse)
mIL6R/iso:1/Clv:soluble
Yes
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0070102
interleukin-6-mediated signaling pathway
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004915
interleukin-6 receptor activity
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
GO:0019981
interleukin-6 binding
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615
extracellular space
PR:000044514
mIL6R/iso:1/Clv:soluble
PMID:8477802