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gene
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PR:000002045 |
interferon regulatory factor 3
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IRF3
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"An interferon regulatory factor 3-9 that is a translation product of the human IRF3 gene or a 1:1 ortholog thereof." [PRO:WCB]
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organism-gene
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PR:P70671 |
interferon regulatory factor 3 (mouse)
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mIRF3
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"An interferon regulatory factor 3 that is encoded in the genome of mouse." [OMA:P70671, PRO:CNA]
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organism-sequence
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PR:C0IXK2 |
interferon regulatory factor 3 isoform 2 (mouse)
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mIRF3/iso:2
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"An interferon regulatory factor 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:C0IXK2." [PMID:18851954, PRO:HJD]
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organism-sequence
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PR:P70671-1 |
interferon regulatory factor 3 isoform 1 (mouse)
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mIRF3/iso:1
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"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-modification
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PR:000027097 |
interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse)
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mIRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70671-1, Ser-378/Ser-379, MOD:00046." [PMID:12872135, PRO:CNA]
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Yes |
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organism-gene
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PR:Q14653 |
interferon regulatory factor 3 (human)
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hIRF3
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"An interferon regulatory factor 3 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q14653-1 |
interferon regulatory factor 3 isoform 1 (human)
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hIRF3/iso:1
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"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000025763 |
interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)
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hIRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]
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Yes |
Yes |
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organism-modification
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PR:000045489 |
interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)
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hIRF3/iso:1/Phos:2
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"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]
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Yes |
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organism-sequence
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PR:Q14653-2 |
interferon regulatory factor 3 isoform h2 (human)
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hIRF3/iso:h2
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"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-2." [PRO:DNx, UniProtKB:Q14653]
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organism-sequence
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PR:Q14653-3 |
interferon regulatory factor 3 isoform h3 (human)
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hIRF3/iso:h3
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"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-3." [PRO:DNx, UniProtKB:Q14653]
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organism-sequence
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PR:Q14653-4 |
interferon regulatory factor 3 isoform h4 (human)
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hIRF3/iso:h4
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"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-4." [PRO:DNx, UniProtKB:Q14653]
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organism-sequence
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PR:Q14653-5 |
interferon regulatory factor 3 isoform h5 (human)
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hIRF3/iso:h5
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"An interferon regulatory factor 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-5." [PRO:DNx, UniProtKB:Q14653]
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organism-modification
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PR:000028702 |
interferon regulatory factor 3 unmodified form (human)
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hIRF3/UnMod
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"An interferon regulatory factor 3 unmodified form in human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000045488 |
interferon regulatory factor 3 phosphorylated 1 (human)
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hIRF3/Phos:1
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"An interferon regulatory factor 3 (human) that has been phosphorylated on residues at positions equivalent to Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, PRO:DAN, Reactome:R-HSA-166258, Reactome:R-HSA-177654]
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Yes |
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organism-modification
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PR:000061027 |
interferon regulatory factor 3, initiator methionine removed form (human)
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hIRF3/InitMet-
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"An interferon regulatory factor 3 (human) that has had the initiator methionine removed. Example: UniProtKB:Q14653-1, 2-427." [PRO:DNx, Reactome:R-HSA-166251]
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organism-modification
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PR:000065516 |
interferon regulatory factor 3 methylated 1 (human)
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hIRF3/Me:1
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"An interferon regulatory factor 3 (human) that has been methylated on the residue at the position equivalent to Met-258 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Met-258, MOD:00716." [IEDB_epitope:431178, PRO:DNx]
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organism-modification
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PR:000075605 |
interferon regulatory factor 3 cysteinylated 1 (human)
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hIRF3/Cyst:1
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"An interferon regulatory factor 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-167 of the amino acid sequence represented by UniProtKB:Q14653-1. Example: UniProtKB:Q14653-1, Cys-167, MOD:00765." [IEDB_epitope:1562127, PRO:DNx]
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sequence
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PR:000003257 |
interferon regulatory factor 3 isoform 1
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IRF3/iso:1
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"An interferon regulatory factor 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14653-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:P70671-1 |
interferon regulatory factor 3 isoform 1 (mouse)
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mIRF3/iso:1
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"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-modification
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PR:000027097 |
interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse)
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mIRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70671-1, Ser-378/Ser-379, MOD:00046." [PMID:12872135, PRO:CNA]
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Yes |
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organism-sequence
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PR:Q14653-1 |
interferon regulatory factor 3 isoform 1 (human)
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hIRF3/iso:1
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"An interferon regulatory factor 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000025763 |
interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)
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hIRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]
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Yes |
Yes |
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organism-modification
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PR:000045489 |
interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)
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hIRF3/iso:1/Phos:2
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"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]
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Yes |
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modification
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PR:000003259 |
interferon regulatory factor 3 isoform 1 phosphorylated form
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IRF3/iso:1/PhosRes+
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"An interferon regulatory factor 3 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000003260 |
interferon regulatory factor 3 isoform 1 phosphorylated 1
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IRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated form in which the phosphorylation occurs upon stimulation by virus infection or treatment with double-stranded RNA or LPS. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:14703513, PMID:20043992, TLR:AMM]
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organism-modification
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PR:000025763 |
interferon regulatory factor 3 isoform 1 phosphorylated 1 (human)
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hIRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q14653-1, Ser-385/Ser-386, MOD:00046." [PMID:10805757, PRO:CNA]
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Yes |
Yes |
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organism-modification
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PR:000027097 |
interferon regulatory factor 3 isoform 1 phosphorylated 1 (mouse)
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mIRF3/iso:1/Phos:1
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"An interferon regulatory factor 3 isoform 1 phosphorylated 1 in mouse. UniProtKB:P70671-1, Ser-378/Ser-379, MOD:00046." [PMID:12872135, PRO:CNA]
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Yes |
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organism-modification
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PR:000045489 |
interferon regulatory factor 3 isoform 1 phosphorylated 2 (human)
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hIRF3/iso:1/Phos:2
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"An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418]
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Yes |
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modification
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PR:000028701 |
interferon regulatory factor 3 unmodified form
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IRF3/UnMod
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"An interferon regulatory factor 3 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
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organism-modification
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PR:000028702 |
interferon regulatory factor 3 unmodified form (human)
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hIRF3/UnMod
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"An interferon regulatory factor 3 unmodified form in human." [PRO:CNA]
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Yes |
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