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Protein Ontology report - DNA-binding protein Ikaros isoform 2
PR:000002151 - http://purl.obolibrary.org/obo/PR_000002151
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000002151   
  PRO nameDNA-binding protein Ikaros isoform 2 
  Synonyms
PRO-Short-label: EXACT:IKZF1/iso:2
Other: EXACT:DNA-binding protein Ikaros isoform Ik6
  Definition"A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-2 or a 1:1 ortholog thereof." [PMID:18623087, PMID:8895580, PRO:DAN, PRO:HJD] 
  CommentNote: This isoform lacks four N-terminal zinc finger domains in comparison to isoform 1, thus functioning as a dominant negative. 
  PRO Categorysequence 
  ParentPR:000001811 DNA-binding protein Ikaros
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000002151

DNA-binding protein Ikaros isoform 2

IKZF1/iso:2


"A DNA-binding protein Ikaros that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03267-2 or a 1:1 ortholog thereof." [PMID:18623087, PMID:8895580, PRO:DAN, PRO:HJD]


organism-sequence



PR:Q03267-2

DNA-binding protein Ikaros isoform I (mouse)

mIKZF1/iso:I


"A DNA-binding protein Ikaros isoform 2 that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:Q13422-6

DNA-binding protein Ikaros isoform Ik6 (human)

hIKZF1/iso:Ik6


"A DNA-binding protein Ikaros isoform 2 that is encoded in the genome of human." [PRO:HJD]