Protein Ontology

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Protein Ontology report - caspase-2

PR:000002311 - http://purl.obolibrary.org/obo/PR_000002311

Protein Forms

Ontology Information

Show OBO stanza

PRO ID

PR:000002311

PRO name

caspase-2

Synonyms

PRO-Short-label:	EXACT:	CASP2
Gene-based:	RELATED:	ICH1 \| NEDD2
Other:	EXACT:	CASP-2 \| NEDD-2 \| neural precursor cell expressed developmentally down-regulated protein 2 \| protease ICH-1

Definition

"A caspase-1-like protease that is a translation product of the human CASP2 gene or a 1:1 ortholog thereof. This protein is involved in the activation cascade of caspases responsible for apoptosis execution." [PRO:WCB]

PRO Category

gene

Parent

PR:000002195 caspase-1-like protease

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	5
Sequence	2	Organism-Sequence	8
Modification	5	Organism-Modification	7

Term Hierarchy
Visualization

DAG:

OLS:

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Related Cross References
Db identifiers	IUPHARobj:1618

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

gene

PR:000002311 caspase-2

CASP2

organism-gene

PR:P29594 caspase-2 (mouse)

mCASP2

organism-sequence

PR:P29594-1 caspase-2 isoform 1 (mouse)

mCASP2/iso:1

organism-gene

PR:P42575 caspase-2 (human)

hCASP2

organism-sequence

PR:P42575-1 caspase-2 isoform 1 (human)

hCASP2/iso:1

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

organism-sequence

PR:P42575-2 caspase-2 isoform 2 (human)

hCASP2/iso:2

organism-sequence

PR:P42575-3 caspase-2 isoform h3 (human)

hCASP2/iso:h3

organism-modification

PR:000045782 caspase-2 phosphorylated 1 (human)

hCASP2/Phos:1

organism-modification

PR:000046570 caspase-2, initiator methionine removed form (human)

hCASP2/InitMet-

organism-modification

PR:000070230 caspase-2 methylated 1 (human)

hCASP2/Me:1

organism-modification

PR:000080352 caspase-2 methylated 2 (human)

hCASP2/Me:2

organism-gene

PR:P55215 caspase-2 (rat)

rCASP2

organism-sequence

PR:P55215-1 caspase-2 isoform r1 (rat)

rCASP2/iso:r1

organism-sequence

PR:P55215-2 caspase-2 isoform r2 (rat)

rCASP2/iso:r2

organism-gene

PR:Q98943 caspase-2 (chicken)

chick-CASP2

organism-sequence

PR:Q98943-1 caspase-2 isoform ICH-1L (chicken)

chick-CASP2/iso:ICH-1L

organism-sequence

PR:Q98943-2 caspase-2 isoform ICH-1S (chicken)

chick-CASP2/iso:ICH-1S

organism-gene

PR:Q9XYF4 caspase Dronc (fruit fly)

fly-CASP2

sequence

PR:000002400 caspase-2 isoform 1

CASP2/iso:1

organism-sequence

PR:P29594-1 caspase-2 isoform 1 (mouse)

mCASP2/iso:1

organism-sequence

PR:P42575-1 caspase-2 isoform 1 (human)

hCASP2/iso:1

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

modification

PR:000002451 caspase-2 subunit p18

CASP2/p18

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

modification

PR:000002452 caspase-2 subunit p13

CASP2/p13

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

modification

PR:000002453 caspase-2 subunit p12

CASP2/p12

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

sequence

PR:000002401 caspase-2 isoform 2

CASP2/iso:2

organism-sequence

PR:P42575-2 caspase-2 isoform 2 (human)

hCASP2/iso:2

modification

PR:000018760 caspase-2, initiator methionine removed form

CASP2/InitMet-

organism-modification

PR:000046570 caspase-2, initiator methionine removed form (human)

hCASP2/InitMet-

modification

PR:000018761 caspase-2 proteolytic cleavage product

CASP2/ClvPrd

modification

PR:000002451 caspase-2 subunit p18

CASP2/p18

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

modification

PR:000002452 caspase-2 subunit p13

CASP2/p13

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

modification

PR:000002453 caspase-2 subunit p12

CASP2/p12

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12