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RACE-PRO
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Protein Ontology report - caspase-8
PR:000002317 -
http://purl.obolibrary.org/obo/PR_000002317
Protein Forms
Complex
Ontology Information
Show OBO stanza
PRO ID
PR:000002317
PRO name
caspase-8
Synonyms
PRO-Short-label
:
EXACT:
CASP8
Gene-based
:
RELATED:
MCH5
Other
:
EXACT:
apoptotic cysteine protease | apoptotic protease Mch-5 | CAP4 | CASP-8 | FADD-homologous ICE/ced-3-like protease | FADD-like ICE | FLICE | ICE-like apoptotic protease 5 | MACH | MORT1-associated ced-3 homolog
Definition
"A caspase-8-like protease that is a translation product of the human CASP8 gene or a 1:1 ortholog thereof." [PRO:WCB]
PRO Category
gene
Parent
PR:000002197
caspase-8-like protease
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
3
Sequence
9
Organism-Sequence
10
Modification
3
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
PIRSF:PIRSF500656
;
IUPHARobj:1624
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
gene
PR:000002317
caspase-8
CASP8
organism-gene
PR:O89110
caspase-8 (mouse)
mCASP8
organism-sequence
PR:O89110-1
caspase-8 isoform 1 (mouse)
mCASP8/iso:1
organism-gene
PR:Q14790
caspase-8 (human)
hCASP8
Yes
organism-sequence
PR:Q14790-1
caspase-8 isoform 1 (human)
hCASP8/iso:1
organism-modification
PR:000036063
caspase-8 isoform 1 cleaved 1 (human)
hCASP8/iso:1/Clv:1
Yes
organism-modification
PR:000036065
caspase-8 isoform 1 cleaved 2 (human)
hCASP8/iso:1/Clv:2
Yes
organism-sequence
PR:Q14790-2
caspase-8 isoform 2 (human)
hCASP8/iso:2
organism-sequence
PR:Q14790-3
caspase-8 isoform 3 (human)
hCASP8/iso:3
organism-sequence
PR:Q14790-4
caspase-8 isoform 4 (human)
hCASP8/iso:4
organism-sequence
PR:Q14790-5
caspase-8 isoform 5 (human)
hCASP8/iso:5
organism-sequence
PR:Q14790-6
caspase-8 isoform 6 (human)
hCASP8/iso:6
organism-sequence
PR:Q14790-7
caspase-8 isoform 7 (human)
hCASP8/iso:7
organism-sequence
PR:Q14790-8
caspase-8 isoform 8 (human)
hCASP8/iso:8
organism-sequence
PR:Q14790-9
caspase-8 isoform 9 (human)
hCASP8/iso:9
organism-modification
PR:000045931
caspase-8 phosphorylated 1 (human)
hCASP8/Phos:1
organism-gene
PR:Q9JHX4
caspase-8 (rat)
rCASP8
sequence
PR:000002412
caspase-8 isoform 1
CASP8/iso:1
organism-sequence
PR:O89110-1
caspase-8 isoform 1 (mouse)
mCASP8/iso:1
organism-sequence
PR:Q14790-1
caspase-8 isoform 1 (human)
hCASP8/iso:1
organism-modification
PR:000036063
caspase-8 isoform 1 cleaved 1 (human)
hCASP8/iso:1/Clv:1
Yes
organism-modification
PR:000036065
caspase-8 isoform 1 cleaved 2 (human)
hCASP8/iso:1/Clv:2
Yes
modification
PR:000036062
caspase-8 isoform 1 cleaved 1
CASP8/iso:1/Clv:1
organism-modification
PR:000036063
caspase-8 isoform 1 cleaved 1 (human)
hCASP8/iso:1/Clv:1
Yes
modification
PR:000036064
caspase-8 isoform 1 cleaved 2
CASP8/iso:1/Clv:2
organism-modification
PR:000036065
caspase-8 isoform 1 cleaved 2 (human)
hCASP8/iso:1/Clv:2
Yes
sequence
PR:000002413
caspase-8 isoform 2
CASP8/iso:2
organism-sequence
PR:Q14790-2
caspase-8 isoform 2 (human)
hCASP8/iso:2
sequence
PR:000002414
caspase-8 isoform 3
CASP8/iso:3
organism-sequence
PR:Q14790-3
caspase-8 isoform 3 (human)
hCASP8/iso:3
sequence
PR:000002415
caspase-8 isoform 4
CASP8/iso:4
organism-sequence
PR:Q14790-4
caspase-8 isoform 4 (human)
hCASP8/iso:4
sequence
PR:000002416
caspase-8 isoform 5
CASP8/iso:5
organism-sequence
PR:Q14790-5
caspase-8 isoform 5 (human)
hCASP8/iso:5
sequence
PR:000002417
caspase-8 isoform 6
CASP8/iso:6
organism-sequence
PR:Q14790-6
caspase-8 isoform 6 (human)
hCASP8/iso:6
sequence
PR:000002418
caspase-8 isoform 7
CASP8/iso:7
organism-sequence
PR:Q14790-7
caspase-8 isoform 7 (human)
hCASP8/iso:7
sequence
PR:000002419
caspase-8 isoform 8
CASP8/iso:8
organism-sequence
PR:Q14790-8
caspase-8 isoform 8 (human)
hCASP8/iso:8
sequence
PR:000002420
caspase-8 isoform 9
CASP8/iso:9
organism-sequence
PR:Q14790-9
caspase-8 isoform 9 (human)
hCASP8/iso:9
modification
PR:000018768
caspase-8 proteolytic cleavage product
CASP8/ClvPrd
modification
PR:000036062
caspase-8 isoform 1 cleaved 1
CASP8/iso:1/Clv:1
organism-modification
PR:000036063
caspase-8 isoform 1 cleaved 1 (human)
hCASP8/iso:1/Clv:1
Yes
modification
PR:000036064
caspase-8 isoform 1 cleaved 2
CASP8/iso:1/Clv:2
organism-modification
PR:000036065
caspase-8 isoform 1 cleaved 2 (human)
hCASP8/iso:1/Clv:2
Yes
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CASP8
forms found in complexes
CASP8
Component
Complexes
PR:000036063
hCASP8/iso:1/Clv:1
PR:000036068
caspase-8 complex (human)
PR:000036065
hCASP8/iso:1/Clv:2
PR:000036068
caspase-8 complex (human)
PR:Q14790
hCASP8
PR:000028435
TRADD:TRAF2:RIP1:FADD:caspase-8 complex (human)
PR:000036060
pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000037368
pro-caspase-8:fadd:rip1:ticam1:activated TLR3 complex (human)
