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Protein Ontology report - caspase-3 isoform 1
PR:000002402 - http://purl.obolibrary.org/obo/PR_000002402
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002402   
  PRO namecaspase-3 isoform 1 
  Synonyms
PRO-Short-label: EXACT:CASP3/iso:1
  Definition"A caspase-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70677-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000002312 caspase-3
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
sequence


PR:000002402
caspase-3 isoform 1
CASP3/iso:1
"A caspase-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70677-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P42574-1
caspase-3 isoform 1 (human)
hCASP3/iso:1
"A caspase-3 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000026876
caspase-3 isoform 1 cleaved 1 (human)
hCASP3/iso:1/Clv:1
"A caspase-3 isoform 1 cleaved 1 in human. UniProtKB:P42574-1, 176-277." [PMID:11931755, PRO:CNA]

Yes
organism-modification


PR:000026877
caspase-3 isoform 1 cleaved 2 (human)
hCASP3/iso:1/Clv:2
"A caspase-3 isoform 1 cleaved 2 in human. UniProtKB:P42574-1, 29-175." [PRO:CNA]

Yes
organism-sequence


PR:P70677-1
caspase-3 isoform 1 (mouse)
mCASP3/iso:1
"A caspase-3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

modification


PR:000002454
caspase-3 isoform 1 cleaved 1
CASP3/iso:1/Clv:1
"A caspase-3 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-3 subunit p12." [PRO:CNA]

Yes
organism-modification


PR:000026876
caspase-3 isoform 1 cleaved 1 (human)
hCASP3/iso:1/Clv:1
"A caspase-3 isoform 1 cleaved 1 in human. UniProtKB:P42574-1, 176-277." [PMID:11931755, PRO:CNA]

Yes
modification


PR:000002455
caspase-3 isoform 1 cleaved 2
CASP3/iso:1/Clv:2
"A caspase-3 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-3 subunit p17." [PRO:CNA]

Yes
organism-modification


PR:000026877
caspase-3 isoform 1 cleaved 2 (human)
hCASP3/iso:1/Clv:2
"A caspase-3 isoform 1 cleaved 2 in human. UniProtKB:P42574-1, 29-175." [PRO:CNA]

Yes
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CASP3/iso:1 forms found in complexes   

CASP3/iso:1 Component
 Complexes
PR:000002454 CASP3/iso:1/Clv:1 PR:000026878 caspase-3 complex
PR:000002455 CASP3/iso:1/Clv:2 PR:000026878 caspase-3 complex
PR:000026876 hCASP3/iso:1/Clv:1 PR:000026879 caspase-3 complex (human)
PR:000026877 hCASP3/iso:1/Clv:2 PR:000026879 caspase-3 complex (human)