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Protein Ontology report - tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated form
PR:000003067 - http://purl.obolibrary.org/obo/PR_000003067
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003067   
  PRO nametyrosine-protein kinase ZAP-70 isoform 1 phosphorylated form 
  Synonyms
PRO-Short-label: EXACT:ZAP70/iso:1/PhosRes+
  Definition"A tyrosine-protein kinase ZAP-70 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA] 
  PRO Categorymodification 
  ParentPR:000003066 tyrosine-protein kinase ZAP-70 isoform 1
PR:000037070 phosphoprotein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification2                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
modification


PR:000003067
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated form
ZAP70/iso:1/PhosRes+
"A tyrosine-protein kinase ZAP-70 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]

modification


PR:000003068
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1
ZAP70/iso:1/Phos:1
"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated form in which the phosphorylation occurs on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck, following TCR engagement. Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. It has been shown that Tyr-319 in the human sequence is required for the positive regulation of ZAP-70 function." [PMID:10037717, PRO:CL]

organism-modification


PR:000036629
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human)
hZAP70/iso:1/Phos:1
"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 in human." [PMID:9269777, PRO:CL]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036629 hZAP70/iso:1/Phos:1 acts_upstream_of_or_withinGO:0090630 activation of GTPase activity PMID:9269777