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Protein Ontology report - lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form

PR:000003298 - http://purl.obolibrary.org/obo/PR_000003298

Protein Forms

Complex

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000003298

PRO name

lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form

Synonyms

PRO-Short-label:	EXACT:	LY96/iso:1/SigPep-/GlycoRes+
Other:	EXACT:	lymphocyte antigen 96 isoform 1 cleaved and glycosylated form

Definition

"A lymphocyte antigen 96 isoform 1, signal peptide removed form that includes at least one glycosylated residue." [PRO:CNA]

PRO Category

modification

Parent

PR:000021940 lymphocyte antigen 96 isoform 1, signal peptide removed form
PR:000037069 glycoprotein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	2	Organism-Modification	2

Term Hierarchy
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DAG:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

modification

PR:000003298 lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form

LY96/iso:1/SigPep-/GlycoRes+

Yes

modification

PR:000003299 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1

LY96/iso:1/SigPep-/NGlyco:1

Yes

organism-modification

PR:000025786 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)

hLY96/iso:1/SigPep-/NGlyco:1

Yes

organism-modification

PR:000027171 lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)

mLY96/iso:1/SigPep-/NGlyco:1

Yes

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LY96/iso:1/SigPep-/GlycoRes+ forms found in complexes

LY96/iso:1/SigPep-/GlycoRes+ Component	Complexes
PR:000003298 LY96/iso:1/SigPep-/GlycoRes+	PR:000036078 TIRAP:PIP2:activated TLR4 complex
PR:000003299 LY96/iso:1/SigPep-/NGlyco:1	PR:000025495 lipopolysaccharide receptor complex 1
	PR:000025496 lipopolysaccharide receptor complex 2
	PR:000025497 lipopolysaccharide receptor complex 3
	PR:000025498 lipopolysaccharide receptor complex 4
PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1	PR:000025773 lipopolysaccharide receptor complex 3 (human)
	PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
	PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
	PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
	PR:000027218 pTIRAP:PIP2:activated TLR4 complex (human)
	PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
	PR:000028678 ticam2:activated TLR4 complex (human)
	PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036004 LY96:TLR4 complex (human)
	PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
	PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
	PR:000036135 TIRAP:PIP2:activated TLR4 complex (human)
	PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
	PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human)
	PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human)
	PR:000037479 lipopolysaccharide receptor complex 4 (human)
	PR:000044684 activated TLR4 complex (human)
PR:000027171 mLY96/iso:1/SigPep-/NGlyco:1	PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)
	PR:000027175 MYD88l:TIRAP:activated TLR4 receptor (mouse)
	PR:000027187 IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse)
	PR:000027196 TIRAP:PIP2:activated TLR4 (mouse)
	PR:000027204 ticam2:activated TLR4 complex (mouse)
	PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000027217 pTIRAP:PIP2:activated TLR4 complex (mouse)
	PR:000027220 IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
	PR:000027221 pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
	PR:000027267 IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
	PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036005 LY96:TLR4 complex (mouse)
	PR:000036077 activated TLR4 complex (mouse)
	PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036095 K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036099 ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036105 pel1:rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
	PR:000037476 lipopolysaccharide receptor complex 3 (mouse)
	PR:000037477 TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
	PR:000037478 pTIRAP:PIP2:BTK:activated TLR4 complex (mouse)
	PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
	PR:000037794 MD2:GB4:TLR4 complex (mouse)

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Functional Annotation (GO-centric view)

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Molecular Function GO Term	Protein Forms & Complexes	Evidence
GO:0001530 lipopolysaccharide binding	PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1	PMID:17569869
GO:1990458 lipooligosaccharide binding	PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1	PMID:19783674
NOT GO:1990458 lipooligosaccharide binding	PR:000027171 mLY96/iso:1/SigPep-/NGlyco:1	PMID:19783674
Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005615 extracellular space	PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1	PMID:19783674
	PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1	PMID:19783674
	PR:000027171 mLY96/iso:1/SigPep-/NGlyco:1	PMID:19783674
GO:0005886 plasma membrane	PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1	Reactome:REACT_7660