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Protein Ontology report - early growth response protein 2
PR:000003469 - http://purl.obolibrary.org/obo/PR_000003469
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003469   
  PRO nameearly growth response protein 2 
  Synonyms
PRO-Short-label: EXACT:EGR2
Gene-based: RELATED:Krox-20 | KROX20 | Zfp-25
Other: EXACT:AT591 | E3 SUMO-protein transferase ERG2 | EGR-2 | zinc finger protein Krox-20
  Definition"A protein that is a translation product of the human EGR2 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000003469

early growth response protein 2

EGR2


"A protein that is a translation product of the human EGR2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P08152

E3 SUMO-protein ligase EGR2 (mouse)

mEGR2


"An early growth response protein 2 that is encoded in the genome of mouse." [OMA:P08152, PRO:DNx]

Yes

organism-sequence



PR:P08152-1

E3 SUMO-protein ligase EGR2 isoform Long (mouse)

mEGR2/iso:Long


"An early growth response protein 2 isoform Long that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:P08152-2

E3 SUMO-protein ligase EGR2 isoform Short (mouse)

mEGR2/iso:Short


"An E3 SUMO-protein ligase EGR2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08152-2." [PRO:DNx, UniProtKB:P08152]

Yes

organism-gene



PR:P11161

E3 SUMO-protein ligase EGR2 (human)

hEGR2


"An early growth response protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P11161]


organism-sequence



PR:P11161-1

E3 SUMO-protein ligase EGR2 isoform Long (human)

hEGR2/iso:Long


"An early growth response protein 2 isoform Long that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P11161-2

E3 SUMO-protein ligase EGR2 isoform Short (human)

hEGR2/iso:Short


"An early growth response protein 2 isoform Short that is encoded in the genome of human." [PRO:HJD]


organism-gene



PR:P51774

E3 SUMO-protein ligase EGR2 (rat)

rEGR2


"An early growth response protein 2 that is encoded in the genome of rat." [OMA:P51774, PRO:DNx]


organism-sequence



PR:P51774-1

E3 SUMO-protein ligase EGR2 isoform Long (rat)

rEGR2/iso:Long


"An E3 SUMO-protein ligase EGR2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51774-1." [PRO:DNx, UniProtKB:P51774]


organism-sequence



PR:P51774-2

E3 SUMO-protein ligase EGR2 isoform Short (rat)

rEGR2/iso:Short


"An E3 SUMO-protein ligase EGR2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51774-2." [PRO:DNx, UniProtKB:P51774]


organism-gene



PR:Q05159

early growth response protein 2b (zebrafish)

z-EGR2


"An early growth response protein 2 that is encoded in the genome of zebrafish." [OMA:Q05159, PRO:DNx]


sequence



PR:000003470

early growth response protein 2 isoform Long

EGR2/iso:Long


"An early growth response protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11161-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P08152-1

E3 SUMO-protein ligase EGR2 isoform Long (mouse)

mEGR2/iso:Long


"An early growth response protein 2 isoform Long that is encoded in the genome of mouse." [PRO:CNA]

Yes

organism-sequence



PR:P11161-1

E3 SUMO-protein ligase EGR2 isoform Long (human)

hEGR2/iso:Long


"An early growth response protein 2 isoform Long that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000022018

early growth response protein 2 isoform Short

EGR2/iso:Short


"An early growth response protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P11161-2 or a 1:1 ortholog thereof." [PRO:HJD, UniProtKB:P08152-2]


organism-sequence



PR:P11161-2

E3 SUMO-protein ligase EGR2 isoform Short (human)

hEGR2/iso:Short


"An early growth response protein 2 isoform Short that is encoded in the genome of human." [PRO:HJD]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P08152 mEGR2 acts_upstream_of_or_withinGO:0006355 regulation of DNA-templated transcription PMID:16136673
GO:0006355 regulation of DNA-templated transcription PMID:16136673
GO:0007622 rhythmic behavior PMID:8893031
GO:0008045 motor neuron axon guidance PMID:9806922
GO:0014037 Schwann cell differentiation PMID:16136673
GO:0021569 rhombomere 3 development PMID:9806922
GO:0021612 facial nerve structural organization PMID:9806922
GO:0021660 rhombomere 3 formation PMID:7903221
GO:0021666 rhombomere 5 formation PMID:7903221
GO:0030278 regulation of ossification PMID:8565822
GO:0042552 myelination PMID:16136673
GO:0042552 myelination PMID:16136673
PR:P08152-1 mEGR2/iso:Long acts_upstream_of_or_withinGO:0007622 rhythmic behavior PMID:8893031
GO:0045944 positive regulation of transcription by RNA polymerase II PMID:8093858
enablesGO:0003677 DNA binding PMID:8093858; PMID:8895582
GO:0003700 DNA-binding transcription factor activity PMID:8093858
located_inGO:0005634 nucleus PMID:15282162
PR:P08152-2 mEGR2/iso:Short enablesGO:0005515 protein binding with PR:Q8C5D8-1 MGI_ref:3629292; PMID:16675951
located_inGO:0005634 nucleus MGI_ref:3629292; PMID:16675951