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Protein Ontology report - double-stranded RNA-specific adenosine deaminase
PR:000003745 - http://purl.obolibrary.org/obo/PR_000003745
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003745   
  PRO namedouble-stranded RNA-specific adenosine deaminase 
  Synonyms
PRO-Short-label: EXACT:ADAR
Gene-based: RELATED:ADAR1 | DSRAD | G1P1 | IFI4
Other: EXACT:136 kDa double-stranded RNA-binding protein | DRADA | IFI-4 | interferon-inducible protein 4 | K88DSRBP | RNA adenosine deaminase 1
  Definition"A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence5                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
gene


PR:000003745 double-stranded RNA-specific adenosine deaminase
ADAR

organism-gene


PR:H9L3K3 uncharacterized protein, ADAR translation product (chicken)
chick-ADAR

organism-gene


PR:P55265 double-stranded RNA-specific adenosine deaminase (human)
hADAR

organism-sequence


PR:P55265-1 double-stranded RNA-specific adenosine deaminase isoform 1 (human)
hADAR/iso:1

organism-sequence


PR:P55265-2 double-stranded RNA-specific adenosine deaminase isoform h2 (human)
hADAR/iso:h2

organism-sequence


PR:P55265-3 double-stranded RNA-specific adenosine deaminase isoform h3 (human)
hADAR/iso:h3

organism-sequence


PR:P55265-4 double-stranded RNA-specific adenosine deaminase isoform h4 (human)
hADAR/iso:h4

organism-sequence


PR:P55265-5 double-stranded RNA-specific adenosine deaminase isoform 5 (human)
hADAR/iso:5

organism-modification


PR:000065283 double-stranded RNA-specific adenosine deaminase cysteinylated 1 (human)
hADAR/Cyst:1

organism-modification


PR:000065658 double-stranded RNA-specific adenosine deaminase methylated 1 (human)
hADAR/Me:1

organism-modification


PR:000066334 double-stranded RNA-specific adenosine deaminase methylated 2 (human)
hADAR/Me:2

organism-modification


PR:000067507 double-stranded RNA-specific adenosine deaminase deaminated 1 (human)
hADAR/Deam:1

organism-modification


PR:000067792 double-stranded RNA-specific adenosine deaminase methylated 3 (human)
hADAR/Me:3

organism-modification


PR:000072266 double-stranded RNA-specific adenosine deaminase methylated 4 (human)
hADAR/Me:4

organism-modification


PR:000078393 double-stranded RNA-specific adenosine deaminase cysteinylated 2 (human)
hADAR/Cyst:2

organism-modification


PR:000082540 double-stranded RNA-specific adenosine deaminase methylated 5 (human)
hADAR/Me:5

organism-modification


PR:000083821 double-stranded RNA-specific adenosine deaminase methylated 6 (human)
hADAR/Me:6

organism-gene


PR:P55266 double-stranded RNA-specific adenosine deaminase (rat)
rADAR

organism-gene


PR:Q99MU3 double-stranded RNA-specific adenosine deaminase (mouse)
mADAR

organism-sequence


PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse)
mADAR/iso:1
Yes
organism-sequence


PR:Q99MU3-2 double-stranded RNA-specific adenosine deaminase isoform 2 (mouse)
mADAR/iso:2
Yes
organism-sequence


PR:Q99MU3-3 double-stranded RNA-specific adenosine deaminase isoform 3 (mouse)
mADAR/iso:3
Yes
organism-sequence


PR:Q99MU3-4 double-stranded RNA-specific adenosine deaminase isoform 4 (mouse)
mADAR/iso:4
Yes
organism-sequence


PR:Q99MU3-5 double-stranded RNA-specific adenosine deaminase isoform 5 (mouse)
mADAR/iso:5

sequence


PR:000037168 double-stranded RNA-specific adenosine deaminase isoform 1
ADAR/iso:1

organism-sequence


PR:P55265-1 double-stranded RNA-specific adenosine deaminase isoform 1 (human)
hADAR/iso:1

organism-sequence


PR:Q99MU3-1 double-stranded RNA-specific adenosine deaminase isoform 1 (mouse)
mADAR/iso:1
Yes
sequence


PR:000037170 double-stranded RNA-specific adenosine deaminase isoform 2
ADAR/iso:2

organism-sequence


PR:Q99MU3-2 double-stranded RNA-specific adenosine deaminase isoform 2 (mouse)
mADAR/iso:2
Yes
sequence


PR:000037172 double-stranded RNA-specific adenosine deaminase isoform 3
ADAR/iso:3

organism-sequence


PR:Q99MU3-3 double-stranded RNA-specific adenosine deaminase isoform 3 (mouse)
mADAR/iso:3
Yes
sequence


PR:000037174 double-stranded RNA-specific adenosine deaminase isoform 4
ADAR/iso:4

organism-sequence


PR:Q99MU3-4 double-stranded RNA-specific adenosine deaminase isoform 4 (mouse)
mADAR/iso:4
Yes
sequence


PR:000037176 double-stranded RNA-specific adenosine deaminase isoform 5
ADAR/iso:5

organism-sequence


PR:P55265-5 double-stranded RNA-specific adenosine deaminase isoform 5 (human)
hADAR/iso:5

organism-sequence


PR:Q99MU3-5 double-stranded RNA-specific adenosine deaminase isoform 5 (mouse)
mADAR/iso:5

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0001701 in utero embryonic developmentPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229
GO:0045071 negative regulation of viral genome replicationPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229
GO:0051607 defense response to virusPR:Q99MU3-1 mADAR/iso:1 MGI_ref:4939544; PMID:21173229

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0003726 double-stranded RNA adenosine deaminase activityPR:Q99MU3-1 mADAR/iso:1 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-2 mADAR/iso:2 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-3 mADAR/iso:3 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-4 mADAR/iso:4 MGI_ref:5515381; PMID:12954622

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005730 nucleolusPR:Q99MU3-3 mADAR/iso:3 MGI_ref:5515381; PMID:12954622
GO:0005737 cytoplasmPR:Q99MU3-1 mADAR/iso:1 MGI_ref:5515381; PMID:12954622
PR:Q99MU3-2 mADAR/iso:2 MGI_ref:5515381; PMID:12954622