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Protein Ontology report - adenomatous polyposis coli protein
PR:000004122 - http://purl.obolibrary.org/obo/PR_000004122
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004122   
  PRO nameadenomatous polyposis coli protein 
  Synonyms
PRO-Short-label: EXACT:APC
Gene-based: RELATED:DP2.5
Other: EXACT:deleted in polyposis 2.5 | protein APC
  Definition"A protein that is a translation product of the human APC gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 85                                        
         Modification5                                                  Organism-Modification 17                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
gene


PR:000004122 adenomatous polyposis coli protein
APC

organism-gene


PR:P25054 adenomatous polyposis coli protein (human)
hAPC
Yes
Yes
organism-sequence


PR:000060341 adenomatous polyposis coli protein sequence variant Q1367* (human)
hAPC/var:Q1367*

organism-sequence


PR:000060552 adenomatous polyposis coli protein sequence variant R876* (human)
hAPC/var:R876*

organism-sequence


PR:000060651 adenomatous polyposis coli protein sequence variant E1379* (human)
hAPC/var:E1379*

organism-sequence


PR:000060672 adenomatous polyposis coli protein sequence variant R302* (human)
hAPC/var:R302*

organism-sequence


PR:000060849 adenomatous polyposis coli protein sequence variant S1315* (human)
hAPC/var:S1315*

organism-sequence


PR:000060863 adenomatous polyposis coli protein sequence variant E941* (human)
hAPC/var:E941*

organism-sequence


PR:000060917 adenomatous polyposis coli protein sequence variant Q1469* (human)
hAPC/var:Q1469*

organism-sequence


PR:000060972 adenomatous polyposis coli protein sequence variant S1539* (human)
hAPC/var:S1539*

organism-sequence


PR:000061011 adenomatous polyposis coli protein sequence variant G1288* (human)
hAPC/var:G1288*

organism-sequence


PR:000061056 adenomatous polyposis coli protein sequence variant R805* (human)
hAPC/var:R805*

organism-sequence


PR:000061099 adenomatous polyposis coli protein sequence variant Y935* (human)
hAPC/var:Y935*

organism-sequence


PR:000061158 adenomatous polyposis coli protein sequence variant S1344* (human)
hAPC/var:S1344*

organism-sequence


PR:000061192 adenomatous polyposis coli protein sequence variant L1564* (human)
hAPC/var:L1564*

organism-sequence


PR:000061287 adenomatous polyposis coli protein sequence variant E1577* (human)
hAPC/var:E1577*

organism-sequence


PR:000061394 adenomatous polyposis coli protein sequence variant S895* (human)
hAPC/var:S895*

organism-sequence


PR:000061450 adenomatous polyposis coli protein sequence variant E1573* (human)
hAPC/var:E1573*

organism-sequence


PR:000061495 adenomatous polyposis coli protein sequence variant Q1328* (human)
hAPC/var:Q1328*

organism-sequence


PR:000061514 adenomatous polyposis coli protein sequence variant K1308* (human)
hAPC/var:K1308*

organism-sequence


PR:000061560 adenomatous polyposis coli protein sequence variant K1310* (human)
hAPC/var:K1310*

organism-sequence


PR:000061672 adenomatous polyposis coli protein sequence variant E1451* (human)
hAPC/var:E1451*

organism-sequence


PR:000061689 adenomatous polyposis coli protein sequence variant S1282* (human)
hAPC/var:S1282*

organism-sequence


PR:000061783 adenomatous polyposis coli protein sequence variant S1356* (human)
hAPC/var:S1356*

organism-sequence


PR:000061802 adenomatous polyposis coli protein sequence variant E1151* (human)
hAPC/var:E1151*

organism-sequence


PR:000061808 adenomatous polyposis coli protein sequence variant E1408* (human)
hAPC/var:E1408*

organism-sequence


PR:000061823 adenomatous polyposis coli protein sequence variant E1374* (human)
hAPC/var:E1374*

organism-sequence


PR:000061902 adenomatous polyposis coli protein sequence variant C1410* (human)
hAPC/var:C1410*

organism-sequence


PR:000061951 adenomatous polyposis coli protein sequence variant L1488* (human)
hAPC/var:L1488*

organism-sequence


PR:000062004 adenomatous polyposis coli protein sequence variant R332* (human)
hAPC/var:R332*

organism-sequence


PR:000062035 adenomatous polyposis coli protein sequence variant E1309* (human)
hAPC/var:E1309*

organism-sequence


PR:000062080 adenomatous polyposis coli protein sequence variant E1536* (human)
hAPC/var:E1536*

organism-sequence


PR:000062099 adenomatous polyposis coli protein sequence variant E1464* (human)
hAPC/var:E1464*

organism-sequence


PR:000062100 adenomatous polyposis coli protein sequence variant S1327* (human)
hAPC/var:S1327*

organism-sequence


PR:000062160 adenomatous polyposis coli protein sequence variant E1397* (human)
hAPC/var:E1397*

organism-sequence


PR:000062179 adenomatous polyposis coli protein sequence variant S1400* (human)
hAPC/var:S1400*

organism-sequence


PR:000062257 adenomatous polyposis coli protein sequence variant R213* (human)
hAPC/var:R213*

organism-sequence


PR:000062325 adenomatous polyposis coli protein sequence variant R1450* (human)
hAPC/var:R1450*

organism-sequence


PR:000062382 adenomatous polyposis coli protein sequence variant S943* (human)
hAPC/var:S943*

organism-sequence


PR:000062413 adenomatous polyposis coli protein sequence variant G1412* (human)
hAPC/var:G1412*

organism-sequence


PR:000062430 adenomatous polyposis coli protein sequence variant E1353* (human)
hAPC/var:E1353*

organism-sequence


PR:000062505 adenomatous polyposis coli protein sequence variant R405* (human)
hAPC/var:R405*

organism-sequence


PR:000062522 adenomatous polyposis coli protein sequence variant R283* (human)
hAPC/var:R283*

organism-sequence


PR:000062533 adenomatous polyposis coli protein sequence variant Q767* (human)
hAPC/var:Q767*

organism-sequence


PR:000062567 adenomatous polyposis coli protein sequence variant E1544* (human)
hAPC/var:E1544*

organism-sequence


PR:000062652 adenomatous polyposis coli protein sequence variant S1346* (human)
hAPC/var:S1346*

organism-sequence


PR:000062666 adenomatous polyposis coli protein sequence variant F1197* (human)
hAPC/var:F1197*

organism-sequence


PR:000062797 adenomatous polyposis coli protein sequence variant E1322* (human)
hAPC/var:E1322*

organism-sequence


PR:000062813 adenomatous polyposis coli protein sequence variant S1392* (human)
hAPC/var:S1392*

organism-sequence


PR:000062815 adenomatous polyposis coli protein sequence variant E1306* (human)
hAPC/var:E1306*

organism-sequence


PR:000062875 adenomatous polyposis coli protein sequence variant Y1376* (human)
hAPC/var:Y1376*

organism-sequence


PR:000062879 adenomatous polyposis coli protein sequence variant G1312* (human)
hAPC/var:G1312*

organism-sequence


PR:000062917 adenomatous polyposis coli protein sequence variant R564* (human)
hAPC/var:R564*

organism-sequence


PR:000062949 adenomatous polyposis coli protein sequence variant E1284* (human)
hAPC/var:E1284*

organism-sequence


PR:000062974 adenomatous polyposis coli protein sequence variant R1386* (human)
hAPC/var:R1386*

organism-sequence


PR:000063233 adenomatous polyposis coli protein sequence variant K1363* (human)
hAPC/var:K1363*

organism-sequence


PR:000063261 adenomatous polyposis coli protein sequence variant S1281* (human)
hAPC/var:S1281*

organism-sequence


PR:000063263 adenomatous polyposis coli protein sequence variant Q886* (human)
hAPC/var:Q886*

organism-sequence


PR:000063548 adenomatous polyposis coli protein sequence variant Q1303* (human)
hAPC/var:Q1303*

organism-sequence


PR:000063804 adenomatous polyposis coli protein sequence variant Q1127* (human)
hAPC/var:Q1127*

organism-sequence


PR:000063808 adenomatous polyposis coli protein sequence variant Q1378* (human)
hAPC/var:Q1378*

organism-sequence


PR:000063820 adenomatous polyposis coli protein sequence variant R1114* (human)
hAPC/var:R1114*

organism-sequence


PR:000063956 adenomatous polyposis coli protein sequence variant W1049* (human)
hAPC/var:W1049*

organism-sequence


PR:000063965 adenomatous polyposis coli protein sequence variant E1554* (human)
hAPC/var:E1554*

organism-sequence


PR:000063968 adenomatous polyposis coli protein sequence variant E1209* (human)
hAPC/var:E1209*

organism-sequence


PR:000064061 adenomatous polyposis coli protein sequence variant K993* (human)
hAPC/var:K993*

organism-sequence


PR:000064078 adenomatous polyposis coli protein sequence variant R554* (human)
hAPC/var:R554*

organism-sequence


PR:000064116 adenomatous polyposis coli protein sequence variant R499* (human)
hAPC/var:R499*

organism-sequence


PR:000064179 adenomatous polyposis coli protein sequence variant E1286* (human)
hAPC/var:E1286*

organism-sequence


PR:000064266 adenomatous polyposis coli protein sequence variant E984* (human)
hAPC/var:E984*

organism-sequence


PR:000064268 adenomatous polyposis coli protein sequence variant Q1429* (human)
hAPC/var:Q1429*

organism-sequence


PR:000064291 adenomatous polyposis coli protein sequence variant R232* (human)
hAPC/var:R232*

organism-sequence


PR:000064330 adenomatous polyposis coli protein sequence variant G1357* (human)
hAPC/var:G1357*

organism-sequence


PR:000064362 adenomatous polyposis coli protein sequence variant Q1294* (human)
hAPC/var:Q1294*

organism-sequence


PR:000064434 adenomatous polyposis coli protein sequence variant E1295* (human)
hAPC/var:E1295*

organism-sequence


PR:000064469 adenomatous polyposis coli protein sequence variant Q1406* (human)
hAPC/var:Q1406*

organism-sequence


PR:000064474 adenomatous polyposis coli protein sequence variant E1345* (human)
hAPC/var:E1345*

organism-sequence


PR:000064598 adenomatous polyposis coli protein sequence variant Q1338* (human)
hAPC/var:Q1338*

organism-sequence


PR:000064608 adenomatous polyposis coli protein sequence variant S811* (human)
hAPC/var:S811*

organism-sequence


PR:000064613 adenomatous polyposis coli protein sequence variant E1317* (human)
hAPC/var:E1317*

organism-sequence


PR:P25054-1 adenomatous polyposis coli protein isoform h1A (human)
hAPC/iso:h1A

organism-modification


PR:000061214 adenomatous polyposis coli protein isoform h1A phosphorylated 1 (human)
hAPC/iso:h1A/Phos:1

organism-modification


PR:000061281 adenomatous polyposis coli protein isoform h1A phosphorylated 2 (human)
hAPC/iso:h1A/Phos:2

organism-modification


PR:000061579 adenomatous polyposis coli protein isoform h1A phosphorylated 3 (human)
hAPC/iso:h1A/Phos:3

organism-modification


PR:000061596 adenomatous polyposis coli protein isoform h1A phosphorylated 4 (human)
hAPC/iso:h1A/Phos:4

organism-sequence


PR:P25054-2 adenomatous polyposis coli protein isoform h2 (human)
hAPC/iso:h2

organism-sequence


PR:P25054-3 adenomatous polyposis coli protein isoform h1B (human)
hAPC/iso:h1B

organism-modification


PR:000030183 adenomatous polyposis coli protein phosphorylated 1 (human)
hAPC/Phos:1

organism-modification


PR:000030185 adenomatous polyposis coli protein phosphorylated 2 (human)
hAPC/Phos:2

organism-modification


PR:000030187 adenomatous polyposis coli protein phosphorylated 3 (human)
hAPC/Phos:3

organism-modification


PR:000030189 adenomatous polyposis coli protein phosphorylated 4 (human)
hAPC/Phos:4

organism-modification


PR:000046350 adenomatous polyposis coli protein phosphorylated and ubiquitinated form (human)
hAPC/PhosUbiq+

organism-modification


PR:000046351 adenomatous polyposis coli protein ubiquitinated form (human)
hAPC/UbiqLys+

organism-modification


PR:000046350 adenomatous polyposis coli protein phosphorylated and ubiquitinated form (human)
hAPC/PhosUbiq+

organism-modification


PR:000056237 adenomatous polyposis coli protein N-glycosylated 1 (human)
hAPC/NGlyco:1

organism-modification


PR:000068028 adenomatous polyposis coli protein cysteinylated 1 (human)
hAPC/Cyst:1

organism-modification


PR:000070520 adenomatous polyposis coli protein methylated 1 (human)
hAPC/Me:1

organism-modification


PR:000073364 adenomatous polyposis coli protein phosphorylated 5 (human)
hAPC/Phos:5

organism-modification


PR:000077353 adenomatous polyposis coli protein cysteinylated 2 (human)
hAPC/Cyst:2

organism-modification


PR:000085314 adenomatous polyposis coli protein methylated 2 (human)
hAPC/Me:2

organism-gene


PR:P70039 adenomatous polyposis coli homolog (frog)
frog-APC

organism-modification


PR:000035395 adenomatous polyposis coli protein phosphorylated 6 (frog)
frog-APC/Phos:6

Yes
organism-gene


PR:P70478 adenomatous polyposis coli protein (rat)
rAPC

organism-gene


PR:Q61315 adenomatous polyposis coli protein (mouse)
mAPC

organism-sequence


PR:Q61315-1 adenomatous polyposis coli protein isoform m1 (mouse)
mAPC/iso:m1

organism-sequence


PR:Q61315-2 adenomatous polyposis coli protein isoform m2 (mouse)
mAPC/iso:m2

organism-sequence


PR:Q61315-3 adenomatous polyposis coli protein isoform m3 (mouse)
mAPC/iso:m3

organism-sequence


PR:Q61315-4 adenomatous polyposis coli protein isoform m4 (mouse)
mAPC/iso:m4

modification


PR:000030182 adenomatous polyposis coli protein phosphorylated 1
APC/Phos:1

organism-modification


PR:000030183 adenomatous polyposis coli protein phosphorylated 1 (human)
hAPC/Phos:1

modification


PR:000030184 adenomatous polyposis coli protein phosphorylated 2
APC/Phos:2

organism-modification


PR:000030185 adenomatous polyposis coli protein phosphorylated 2 (human)
hAPC/Phos:2

modification


PR:000030186 adenomatous polyposis coli protein phosphorylated 3
APC/Phos:3

organism-modification


PR:000030187 adenomatous polyposis coli protein phosphorylated 3 (human)
hAPC/Phos:3

modification


PR:000030188 adenomatous polyposis coli protein phosphorylated 4
APC/Phos:4

organism-modification


PR:000030189 adenomatous polyposis coli protein phosphorylated 4 (human)
hAPC/Phos:4

modification


PR:000035394 adenomatous polyposis coli protein phosphorylated 6
APC/Phos:6

organism-modification


PR:000035395 adenomatous polyposis coli protein phosphorylated 6 (frog)
frog-APC/Phos:6

Yes
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APC forms found in complexes   

APC Component
 Complexes
PR:000035395 frog-APC/Phos:6 PR:000035398 BUB1B:APC:EB1 complex (frog)
PR:P25054 hAPC PR:000035576 BUB1:BUB3:APC complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P25054 hAPC acts_upstream_of_or_withinGO:0007059 chromosome segregation PMID:11283619
NOT GO:0031577 spindle checkpoint signaling PMID:11283619
enablesGO:0005515 protein binding with PR:O14641 dishevelled-2 (human) BioGRID:BG-302957
GO:0005515 protein binding with PR:O43683 BUB1 BioGRID:BG-302957
GO:0005515 protein binding with PR:O43684 BUB3 BioGRID:BG-302957
GO:0005515 protein binding with PR:Q13257 hMAD2L1 BioGRID:BG-302957
GO:0008017 microtubule binding PMID:11283619
located_inGO:0000776 kinetochore PMID:11283619