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Protein Ontology report - F-actin-capping protein subunit beta
PR:000005032 - http://purl.obolibrary.org/obo/PR_000005032
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000005032   
  PRO nameF-actin-capping protein subunit beta 
  Synonyms
PRO-Short-label: EXACT:CAPZB
Gene-based: RELATED:Cappb1
Other: EXACT:CapZ beta
  Definition"A protein that is a translation product of the human CAPZB gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 10                                        
         Sequence3                                                  Organism-Sequence 8                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000005032

F-actin-capping protein subunit beta

CAPZB


"A protein that is a translation product of the human CAPZB gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P13021

F-actin-capping protein subunit beta (Dictyostelium discoideum)

Dicty-CAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of Dictyostelium discoideum." [OMA:P13021, PRO:DNx]


organism-gene



PR:P13517

F-actin-capping protein subunit beta (yeast)

yCAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of yeast." [OMA:P13517, PRO:DNx]


organism-gene



PR:P14315

F-actin-capping protein subunit beta isoforms 1 and 2 (chicken)

chick-CAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of chicken." [OMA:P14315, PRO:DNx]


organism-sequence



PR:P14315-1

F-actin-capping protein subunit beta isoforms 1 and 2 isoform 1 (chicken)

chick-CAPZB/iso:1


"An F-actin-capping protein subunit beta isoforms 1 and 2 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14315-1." [PRO:DNx, UniProtKB:P14315]


organism-sequence



PR:P14315-2

F-actin-capping protein subunit beta isoforms 1 and 2 isoform 2 (chicken)

chick-CAPZB/iso:2


"An F-actin-capping protein subunit beta isoforms 1 and 2 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14315-2." [PRO:DNx, UniProtKB:P14315]


organism-gene



PR:P34686

F-actin-capping protein subunit beta (worm)

CAPZB (worm)


"An F-actin-capping protein subunit beta that is encoded in the genome of worm." [OMA:P34686, PRO:DNx]


organism-gene



PR:P47756

F-actin-capping protein subunit beta (human)

hCAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P47756]


organism-sequence



PR:P47756-1

F-actin-capping protein subunit beta isoform h2 (human)

hCAPZB/iso:h2


"An F-actin-capping protein subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47756-1." [PRO:DNx, UniProtKB:P47756]


organism-sequence



PR:P47756-2

F-actin-capping protein subunit beta isoform h1 (human)

hCAPZB/iso:h1


"An F-actin-capping protein subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47756-2." [PRO:DNx, UniProtKB:P47756]


organism-sequence



PR:P47756-3

F-actin-capping protein subunit beta isoform h3 (human)

hCAPZB/iso:h3


"An F-actin-capping protein subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47756-3." [PRO:DNx, UniProtKB:P47756]


organism-modification



PR:000046565

F-actin-capping protein subunit beta, initiator methionine removed form (human)

hCAPZB/InitMet-


"An F-actin-capping protein subunit beta (human) that has had the initiator methionine removed. UniProtKB:P47756, 2-272." [PRO:DNx, Reactome:R-HSA-879409]


organism-modification



PR:000066575

F-actin-capping protein subunit beta methylated 1 (human)

hCAPZB/Me:1


"An F-actin-capping protein subunit beta (human) that has been methylated on the residue at the position equivalent to Cys-272 of the amino acid sequence represented by UniProtKB:P47756-2. Example: UniProtKB:P47756-2, Cys-272, MOD:00660." [IEDB_epitope:1032321, PRO:DNx]


organism-gene



PR:P47757

F-actin-capping protein subunit beta (mouse)

mCAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of mouse." [OMA:P47757, PRO:DNx]


organism-sequence



PR:P47757-1

F-actin-capping protein subunit beta isoform 1 (mouse)

mCAPZB/iso:1


"An F-actin-capping protein subunit beta isoform 1 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]

Yes

organism-sequence



PR:P47757-2

F-actin-capping protein subunit beta isoform 2 (mouse)

mCAPZB/iso:2


"An F-actin-capping protein subunit beta isoform 2 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]

Yes

Yes
organism-sequence



PR:P47757-4

F-actin-capping protein subunit beta isoform Capzb3 (mouse)

mCAPZB/iso:Capzb3


"An F-actin-capping protein subunit beta isoform Capzb3 that is encoded in the genome of mouse." [PMID:19341723, PRO:KRC]

Yes

organism-gene



PR:P48603

F-actin-capping protein subunit beta (fruit fly)

fly-CAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of fruit fly." [OMA:P48603, PRO:DNx]


organism-gene



PR:Q5XI32

F-actin-capping protein subunit beta (rat)

rCAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of rat." [OMA:Q5XI32, PRO:DNx]


organism-gene



PR:Q9HGP5

F-actin-capping protein subunit beta (Schizosaccharomyces pombe 972h-)

Spom972h-CAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9HGP5, PRO:DNx]


organism-gene



PR:Q9M9G7

probable F-actin-capping protein subunit beta (Arabidopsis thaliana)

At-CAPZB


"An F-actin-capping protein subunit beta that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9M9G7, PRO:DNx]


sequence



PR:000035824

F-actin-capping protein subunit beta isoform 1

CAPZB/iso:1


"An F-actin-capping protein subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47757-1 or a 1:1 ortholog thereof." [PMID:10601341, PRO:KRC]


organism-sequence



PR:P47757-1

F-actin-capping protein subunit beta isoform 1 (mouse)

mCAPZB/iso:1


"An F-actin-capping protein subunit beta isoform 1 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]

Yes

sequence



PR:000035826

F-actin-capping protein subunit beta isoform 2

CAPZB/iso:2


"An F-actin-capping protein subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47757-2 or a 1:1 ortholog thereof." [PMID:10601341, PRO:KRC]


organism-sequence



PR:P47757-2

F-actin-capping protein subunit beta isoform 2 (mouse)

mCAPZB/iso:2


"An F-actin-capping protein subunit beta isoform 2 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]

Yes

Yes
sequence



PR:000035828

F-actin-capping protein subunit beta isoform Capzb3

CAPZB/iso:Capzb3


"An F-actin-capping protein subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47757-4 or a 1:1 ortholog thereof." [PMID:19341723, PRO:KRC]


organism-sequence



PR:P47757-4

F-actin-capping protein subunit beta isoform Capzb3 (mouse)

mCAPZB/iso:Capzb3


"An F-actin-capping protein subunit beta isoform Capzb3 that is encoded in the genome of mouse." [PMID:19341723, PRO:KRC]

Yes

modification



PR:000019237

F-actin-capping protein subunit beta, initiator methionine removed form

CAPZB/InitMet-


"An F-actin-capping protein subunit beta that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000046565

F-actin-capping protein subunit beta, initiator methionine removed form (human)

hCAPZB/InitMet-


"An F-actin-capping protein subunit beta (human) that has had the initiator methionine removed. UniProtKB:P47756, 2-272." [PRO:DNx, Reactome:R-HSA-879409]


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CAPZB forms found in complexes   

CAPZB Component
Complexes
PR:P47757ZDASHZ2 mCAPZB/iso:2 PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)
PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P47757-1 mCAPZB/iso:1 acts_upstream_of_or_withinGO:0055001 muscle cell development MGI_ref:1350695; PMID:10601341
GO:0090036 regulation of protein kinase C signaling MGI_ref:3777904; PMID:12089068
located_inGO:0030018 Z disc MGI_ref:68935; PMID:7929588
GO:0030018 Z disc MGI_ref:68935; PMID:7929588
PR:P47757-2 mCAPZB/iso:2 acts_upstream_of_or_withinGO:0030032 lamellipodium assembly MGI_ref:4397629; PMID:19806181
GO:0031115 negative regulation of microtubule polymerization MGI_ref:4397629; PMID:19806181
GO:0031175 neuron projection development MGI_ref:4397629; PMID:19806181
GO:0051016 barbed-end actin filament capping MGI_ref:3758397; PMID:17656356
GO:0055001 muscle cell development MGI_ref:1350695; PMID:10601341
enablescontributes_to GO:0005515 protein binding with PR:Q91YR1 mTWF1 MGI_ref:3773286; PMID:11604420
GO:0048487 beta-tubulin binding MGI_ref:4397629; PMID:19806181
contributes_to GO:0051015 actin filament binding MGI_ref:3758397; PMID:17656356
located_inGO:0008290 F-actin capping protein complex MGI_ref:4397629; PMID:19806181
GO:0008290 F-actin capping protein complex with PR:P47754 Cappa2 MGI_ref:4397629; PMID:19806181
GO:0014704 intercalated disc MGI_ref:68935; PMID:7929588
GO:0014704 intercalated disc MGI_ref:68935; PMID:7929588
PR:P47757-4 mCAPZB/iso:Capzb3 located_incolocalizes_with GO:0001669 acrosomal vesicle MGI_ref:3848085; PMID:19341723