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Protein Ontology report - serine/threonine-protein kinase Chk1
PR:000005417 - http://purl.obolibrary.org/obo/PR_000005417
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000005417   
  PRO nameserine/threonine-protein kinase Chk1 
  Synonyms
PRO-Short-label: EXACT:CHEK1
Gene-based: RELATED:CHK1
Other: EXACT:checkpoint kinase 1 | checkpoint kinase-1 | CHK1 checkpoint homolog
  Definition"A protein that is a translation product of the human CHEK1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1987
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000005417

serine/threonine-protein kinase Chk1

CHEK1


"A protein that is a translation product of the human CHEK1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O14757

serine/threonine-protein kinase Chk1 (human)

hCHEK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:O14757-1

serine/threonine-protein kinase Chk1 isoform 1 (human)

hCHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O14757-2

serine/threonine-protein kinase Chk1 isoform 2 (human)

hCHEK1/iso:2


"A serine/threonine-protein kinase Chk1 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O14757-3

serine/threonine-protein kinase Chk1 isoform h3 (human)

hCHEK1/iso:h3


"A serine/threonine-protein kinase Chk1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14757-3." [PRO:DNx, UniProtKB:O14757]


organism-modification



PR:000045568

serine/threonine-protein kinase Chk1 phosphorylated 1 (human)

hCHEK1/Phos:1


"A serine/threonine-protein kinase Chk1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-345 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Ser-345, MOD:00046." [iPTMnet:O14757, PMID:10859164, PMID:14681223, PMID:15533933]


organism-modification



PR:000046701

serine/threonine-protein kinase Chk1 phosphorylated 2 (human)

hCHEK1/Phos:2


"A serine/threonine-protein kinase Chk1 (human) that has been post-translationally modified to include phosphoserine at positions 317 and 345 of the amino acid sequence represented by UniProtKB:O14757. UniProtKB:O14757, Ser-317/Ser-345, MOD:00046." [PRO:DNx, Reactome:R-HSA-113838]


organism-modification



PR:000071876

serine/threonine-protein kinase Chk1 deaminated 1 (human)

hCHEK1/Deam:1


"A serine/threonine-protein kinase Chk1 (human) that has been deaminated on the residue at the position equivalent to Asn-135 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Asn-135, MOD:00684." [IEDB_epitope:1564062, PRO:DNx]


organism-modification



PR:000073649

serine/threonine-protein kinase Chk1 methylated 1 (human)

hCHEK1/Me:1


"A serine/threonine-protein kinase Chk1 (human) that has been methylated on the residue at the position equivalent to Cys-349 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Cys-349, MOD:00660." [IEDB_epitope:1038944, PRO:DNx]


organism-modification



PR:000076757

serine/threonine-protein kinase Chk1 methylated 2 (human)

hCHEK1/Me:2


"A serine/threonine-protein kinase Chk1 (human) that has been methylated on the residue at the position equivalent to Cys-408 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Cys-408, MOD:00660." [IEDB_epitope:1026404, PRO:DNx]


organism-modification



PR:000078276

serine/threonine-protein kinase Chk1 phosphorylated 3 (human)

hCHEK1/Phos:3


"A serine/threonine-protein kinase Chk1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-467 of the amino acid sequence represented by UniProtKB:O14757-1. Example: UniProtKB:O14757-1, Ser-467, MOD:00046." [IEDB_epitope:1319645, PRO:DNx]


organism-gene



PR:O35280

serine/threonine-protein kinase Chk1 (mouse)

mCHEK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of mouse." [OMA:O35280, PRO:DNx]


organism-sequence



PR:O35280-1

serine/threonine-protein kinase Chk1 isoform 1 (mouse)

mCHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:O35280-2

serine/threonine-protein kinase Chk1 isoform 2 (mouse)

mCHEK1/iso:2


"A serine/threonine-protein kinase Chk1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:O61661

serine/threonine-protein kinase grp (fruit fly)

fly-CHEK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of fruit fly." [OMA:O61661, PRO:DNx]


organism-gene



PR:P38147

serine/threonine-protein kinase CHK1 (yeast)

yCHK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of yeast." [PRO:DAN]


organism-gene



PR:Q8AYC9

serine/threonine-protein kinase Chk1 (chicken)

chick-CHEK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of chicken." [OMA:Q8AYC9, PRO:DNx]


organism-sequence



PR:Q8AYC9-1

serine/threonine-protein kinase Chk1 isoform 1 (chicken)

chick-CHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:Q93VD3

CBL-interacting serine/threonine-protein kinase 23 (Arabidopsis thaliana)

At-CHEK1


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q93VD3, PRO:DNx]


organism-gene



PR:Q9N3Z3

serine/threonine-protein kinase chk-1 (worm)

CHEK1 (worm)


"A serine/threonine-protein kinase Chk1 that is encoded in the genome of worm." [OMA:Q9N3Z3, PRO:DNx]


organism-sequence



PR:Q9N3Z3-1

serine/threonine-protein kinase chk-1 isoform a (worm)

CHEK1/iso:a (worm)


"A serine/threonine-protein kinase chk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9N3Z3-1." [PRO:DNx, UniProtKB:Q9N3Z3]


organism-sequence



PR:Q9N3Z3-2

serine/threonine-protein kinase chk-1 isoform b (worm)

CHEK1/iso:b (worm)


"A serine/threonine-protein kinase chk-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9N3Z3-2." [PRO:DNx, UniProtKB:Q9N3Z3]


sequence



PR:000037997

serine/threonine-protein kinase Chk1 isoform 1

CHEK1/iso:1


"A serine/threonine-protein kinase Chk1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14757-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O14757-1

serine/threonine-protein kinase Chk1 isoform 1 (human)

hCHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O35280-1

serine/threonine-protein kinase Chk1 isoform 1 (mouse)

mCHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q8AYC9-1

serine/threonine-protein kinase Chk1 isoform 1 (chicken)

chick-CHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-sequence



PR:Q91ZN7-1

serine/threonine-protein kinase Chk1 isoform 1 (rat)

rCHEK1/iso:1


"A serine/threonine-protein kinase Chk1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000037998

serine/threonine-protein kinase Chk1 isoform 2

CHEK1/iso:2


"A serine/threonine-protein kinase Chk1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14757-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O14757-2

serine/threonine-protein kinase Chk1 isoform 2 (human)

hCHEK1/iso:2


"A serine/threonine-protein kinase Chk1 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O35280-2

serine/threonine-protein kinase Chk1 isoform 2 (mouse)

mCHEK1/iso:2


"A serine/threonine-protein kinase Chk1 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]