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Protein Ontology report - eukaryotic translation initiation factor 4E-binding protein 1
PR:000006994 - http://purl.obolibrary.org/obo/PR_000006994
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000006994   
  PRO nameeukaryotic translation initiation factor 4E-binding protein 1 
  Synonyms
PRO-Short-label: EXACT:EIF4EBP1
Other: EXACT:4E-BP1 | eIF4E-binding protein 1 | PHAS-I | phosphorylated heat- and acid-stable protein regulated by insulin 1
  Definition"A protein that is a translation product of the human EIF4EBP1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification5                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
gene


PR:000006994
eukaryotic translation initiation factor 4E-binding protein 1
EIF4EBP1
"A protein that is a translation product of the human EIF4EBP1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q13541
eukaryotic translation initiation factor 4E-binding protein 1 (human)
hEIF4EBP1
"A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13541]

organism-sequence


PR:Q13541-1
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (human)
hEIF4EBP1/iso:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026216
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 (human)
hEIF4EBP1/iso:1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047." [PRO:CNx, Reactome:R-HSA-165685]

organism-modification


PR:000028425
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human)
hEIF4EBP1/InitMet-
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form in human. UniProtKB:Q13541, 2-118." [PRO:DNx]

Yes
organism-modification


PR:000044853
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated 1 (human)
hEIF4EBP1/InitMet-/Ac:1
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060." [PRO:DAN, TDR:2130]

organism-modification


PR:000044854
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated and phosphorylated 1 (human)
hEIF4EBP1/InitMet-/AcPhos:1
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser and phosphorylated on Ser-94. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94, MOD:00046." [PRO:DAN, TDR:2640]

organism-modification


PR:000044855
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated and phosphorylated 2 (human)
hEIF4EBP1/InitMet-/AcPhos:2
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser and phosphorylated on Ser-94 and Ser-101. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94/Ser-101, MOD:00046." [TDR:2642]

organism-modification


PR:000035490
eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1 (human)
hEIF4EBP1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1 in human." [PMID:10198256, PRO:KER]

organism-gene


PR:Q60876
eukaryotic translation initiation factor 4E-binding protein 1 (mouse)
mEIF4EBP1
"A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of mouse." [OMA:Q60876, PRO:DNx]

organism-sequence


PR:Q60876-1
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (mouse)
mEIF4EBP1/iso:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

organism-modification


PR:000079349
eukaryotic translation initiation factor 4E-binding protein 1 deaminated 1 (mouse)
mEIF4EBP1/Deam:1
"A eukaryotic translation initiation factor 4E-binding protein 1 (mouse) that has been deaminated on the residue at the position equivalent to Gln-9 of the amino acid sequence represented by UniProtKB:Q60876. UniProtKB:Q60876, Gln-9, MOD:00685." [IEDB_epitope:238189, PRO:DNx]

organism-gene


PR:Q62622
eukaryotic translation initiation factor 4E-binding protein 1 (rat)
rEIF4EBP1
"A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of rat." [OMA:Q62622, PRO:DNx]

organism-modification


PR:000029018
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 (rat)
rEIF4EBP1/iso:1/Phos:2
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 in rat. UniProtKB:Q62622-1, Ser-64, MOD:00046." [PMID:7939721, PRO:CNA]
Yes
organism-gene


PR:Q6PFS8
uncharacterized protein, eif4ebp1 translation product (zebrafish)
z-EIF4EBP1
"A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of zebrafish." [PRO:DNx]

sequence


PR:000026204
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1
EIF4EBP1/iso:1
"A eukaryotic translation initiation factor 4E-binding protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13541-1 or a 1:1 ortholog thereof." [PRO:CNx]

organism-sequence


PR:Q13541-1
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (human)
hEIF4EBP1/iso:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026216
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 (human)
hEIF4EBP1/iso:1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047." [PRO:CNx, Reactome:R-HSA-165685]

organism-sequence


PR:Q60876-1
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (mouse)
mEIF4EBP1/iso:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

modification


PR:000026206
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1
EIF4EBP1/iso:1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has been phosphorylated by activated mTORC1. Example: UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047." [PRO:CNx, Reactome:R-HSA-165685]

organism-modification


PR:000026216
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 (human)
hEIF4EBP1/iso:1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047." [PRO:CNx, Reactome:R-HSA-165685]

modification


PR:000026578
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1, initiator methionine removed form
EIF4EBP1/iso:1/InitMet-
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]

modification


PR:000029017
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2
EIF4EBP1/iso:1/Phos:2
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has been phosphorylated by MAP kinases. Example: UniProtKB:Q62622-1, Ser-64, MOD:00046." [PMID:7939721, PRO:CNA]

organism-modification


PR:000029018
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 (rat)
rEIF4EBP1/iso:1/Phos:2
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 in rat. UniProtKB:Q62622-1, Ser-64, MOD:00046." [PMID:7939721, PRO:CNA]
Yes
modification


PR:000019769
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form
EIF4EBP1/InitMet-
"A eukaryotic translation initiation factor 4E-binding protein 1 that has had the initiator methionine removed." [PRO:DNx]

modification


PR:000026578
eukaryotic translation initiation factor 4E-binding protein 1 isoform 1, initiator methionine removed form
EIF4EBP1/iso:1/InitMet-
"A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000028425
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human)
hEIF4EBP1/InitMet-
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form in human. UniProtKB:Q13541, 2-118." [PRO:DNx]

Yes
organism-modification


PR:000044853
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated 1 (human)
hEIF4EBP1/InitMet-/Ac:1
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060." [PRO:DAN, TDR:2130]

organism-modification


PR:000044854
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated and phosphorylated 1 (human)
hEIF4EBP1/InitMet-/AcPhos:1
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser and phosphorylated on Ser-94. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94, MOD:00046." [PRO:DAN, TDR:2640]

organism-modification


PR:000044855
eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated and phosphorylated 2 (human)
hEIF4EBP1/InitMet-/AcPhos:2
"A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser and phosphorylated on Ser-94 and Ser-101. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94/Ser-101, MOD:00046." [TDR:2642]

modification


PR:000035489
eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1
EIF4EBP1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 that has been post-translationally modified by BUB1." [PMID:10198256, PRO:KER]

organism-modification


PR:000035490
eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1 (human)
hEIF4EBP1/Phos:1
"A eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1 in human." [PMID:10198256, PRO:KER]

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EIF4EBP1 forms found in complexes   

EIF4EBP1 Component
 Complexes
PR:000028425 hEIF4EBP1/InitMet- PR:000028454 eIF4E:4E-BP (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000029018 rEIF4EBP1/iso:1/Phos:2
UniProtKB:Q62622-1, Ser-64, MOD:00046		 enablesNOT GO:0031369 translation initiation factor binding PMID:7939721