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Protein Ontology report - hemoglobin subunit alpha
PR:000008456 - http://purl.obolibrary.org/obo/PR_000008456
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000008456   
  PRO namehemoglobin subunit alpha 
  Synonyms
PRO-Short-label: EXACT:HBA[1/2]
Gene-based: RELATED:HBA1 | HBA2
Other: EXACT:hemoglobin subunit alpha-2
  Definition"A hemoglobin subunit that is a translation product of the human HBA1 or HBA2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DNx] 
  CommentNote: The human HBA1 and HBA2 genes encode identical proteins. 
  PRO Categorygene 
  ParentPR:000050467 hemoglobin subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000008456

hemoglobin subunit alpha

HBA[1/2]


"A hemoglobin subunit that is a translation product of the human HBA1 or HBA2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DNx]


organism-gene



PR:P01942

hemoglobin subunit alpha (mouse)

mHba


"A hemoglobin subunit alpha that is encoded in the genome of mouse." [OMA:P01942, PRO:DNx]


organism-modification



PR:000070280

hemoglobin subunit alpha cysteinylated 1 (mouse)

mHba/Cyst:1


"A hemoglobin subunit alpha (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-105 of the amino acid sequence represented by UniProtKB:P01942. UniProtKB:P01942, Cys-105, MOD:00765." [IEDB_epitope:2098767, PRO:DNx]


organism-modification



PR:000084167

hemoglobin subunit alpha deaminated 1 (mouse)

mHba/Deam:1


"A hemoglobin subunit alpha (mouse) that has been deaminated on the residue at the position equivalent to Asn-98 of the amino acid sequence represented by UniProtKB:P01942. UniProtKB:P01942, Asn-98, MOD:00684." [IEDB_epitope:2137052, PRO:DNx]


organism-gene



PR:P01994

hemoglobin subunit alpha-A (chicken)

chick-HBA[1/2]


"A hemoglobin subunit alpha that is encoded in the genome of chicken." [OMA:P01994, PRO:DNx]


organism-sequence



PR:P01994-1

hemoglobin subunit alpha-A isoform 1 (chicken)

chick-HBA2/iso:1


"A hemoglobin subunit alpha isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:P69905

hemoglobin subunit alpha (human)

hHBA


"A hemoglobin subunit alpha that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P69905-1

hemoglobin subunit alpha isoform 1 (human)

hHBA/iso:1


"A hemoglobin subunit alpha isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000060496

hemoglobin subunit alpha, initiator methionine removed carboxylated and protonated 1 (human)

hHBA/InitMet-/Cbxprot:1


"A hemoglobin subunit alpha (human) that has had the initiator methionine removed, that has been carboxylated on the residue at the position equivalent to Val-2 of the amino acid sequence represented by UniProtKB:P69905, and that includes at least 1 protonated residue. UniProtKB:P69905, 2-142, Val-2, MOD:01874|MOD:01699." [PRO:DNx, Reactome:R-HSA-1237026]


organism-modification



PR:000062125

hemoglobin subunit alpha, initiator methionine removed form (human)

hHBA/InitMet-


"A hemoglobin subunit alpha (human) that has had the initiator methionine removed. UniProtKB:P69905, 2-142." [PRO:DNx, Reactome:R-HSA-1008268, Reactome:R-HSA-2168862, Reactome:R-HSA-2230966]


organism-modification



PR:000067719

hemoglobin subunit alpha methylated 1 (human)

hHBA/Me:1


"A hemoglobin subunit alpha (human) that has been methylated on the residue at the position equivalent to Glu-24 of the amino acid sequence represented by UniProtKB:P69905. UniProtKB:P69905, Glu-24, MOD:00713." [IEDB_epitope:1317929, PRO:DNx]


organism-modification



PR:000071827

hemoglobin subunit alpha deaminated 1 (human)

hHBA/Deam:1


"A hemoglobin subunit alpha (human) that has been deaminated on the residue at the position equivalent to Asn-79 of the amino acid sequence represented by UniProtKB:P69905. UniProtKB:P69905, Asn-79, MOD:00684." [IEDB_epitope:1807957, IEDB_epitope:995859, PRO:DNx]


organism-modification



PR:000081750

hemoglobin subunit alpha citrullinated 1 (human)

hHBA/Cit:1


"A hemoglobin subunit alpha (human) that has been citrullinated on the residue at the position equivalent to Arg-142 of the amino acid sequence represented by UniProtKB:P69905. UniProtKB:P69905, Arg-142, MOD:00219." [IEDB_epitope:434686, PRO:DNx]


sequence



PR:000040115

hemoglobin subunit alpha isoform 1

HBA/iso:1


"A hemoglobin subunit alpha that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P69905-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P01994-1

hemoglobin subunit alpha-A isoform 1 (chicken)

chick-HBA2/iso:1


"A hemoglobin subunit alpha isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-sequence



PR:P69905-1

hemoglobin subunit alpha isoform 1 (human)

hHBA/iso:1


"A hemoglobin subunit alpha isoform 1 that is encoded in the genome of human." [PRO:DNx]


modification



PR:000020113

hemoglobin subunit alpha, initiator methionine removed form

HBA/InitMet-


"A hemoglobin subunit alpha that has had the initiator methionine removed." [PRO:DNx]


Yes
modification



PR:000060266

hemoglobin subunit alpha, initiator methionine removed carbon dioxide bound form

HBA/InitMet-/carbamino


"A hemoglobin subunit alpha, initiator methionine removed form that has formed a carbamate with carbon dioxide at the position equivalent to Val-2 of the sequence represented by UniProtKB:P68871-1 or a 1:1 ortholog thereof." [PRO:DAN]


Yes
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HBA[1/2] forms found in complexes   

HBA[1/2] Component
Complexes
PR:000020113 HBA/InitMet- PR:000050469 hemoglobin A1c
PR:000060250 methemoglobin
PR:000060251 carboxyhemoglobin
PR:000060254 oxyhemoglobin
PR:000060255 deoxyhemoglobin
PR:000060266 HBA/InitMet-/carbamino PR:000060252 carbaminohemoglobin