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Protein Ontology report - hypermethylated in cancer 1 protein
PR:000008551 - http://purl.obolibrary.org/obo/PR_000008551
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000008551   
  PRO namehypermethylated in cancer 1 protein 
  Synonyms
PRO-Short-label: EXACT:HIC1
Gene-based: RELATED:ZBTB29
Other: EXACT:Hic-1 | zinc finger and BTB domain-containing protein 29
  Definition"A protein that is a translation product of the human HIC1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence2                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000008551

hypermethylated in cancer 1 protein

HIC1


"A protein that is a translation product of the human HIC1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q14526

hypermethylated in cancer 1 protein (human)

hHIC1


"A hypermethylated in cancer 1 protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14526]


organism-sequence



PR:Q14526-1

hypermethylated in cancer 1 protein isoform 1 (human)

hHIC1/iso:1


"A hypermethylated in cancer 1 protein isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-sequence



PR:Q14526-2

hypermethylated in cancer 1 protein isoform 2 (human)

hHIC1/iso:2


"A hypermethylated in cancer 1 protein isoform 2 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028784

hypermethylated in cancer 1 protein isoform 2 acetylated 1 (human)

hHIC1/iso:2/Ac:1


"A hypermethylated in cancer 1 protein isoform 2 acetylated 1 in human. Acetylation regulates transcriptional repression activity. UniProtKB:Q14526-2, Lys-314, MOD:00064." [PMID:17283066, PRO:PD]


organism-modification



PR:000064776

hypermethylated in cancer 1 protein sumoylated 1 (human)

hHIC1/Sumo:1


"A hypermethylated in cancer 1 protein (human) that has been sumoylated on the residue at the position equivalent to Lys-333 of the amino acid sequence represented by UniProtKB:Q14526-1. Example: UniProtKB:Q14526-1, Lys-333, MOD:01149." [PRO:DNx, Reactome:R-HSA-4090368]


organism-gene



PR:Q9R1Y5

hypermethylated in cancer 1 protein (mouse)

mHIC1


"A hypermethylated in cancer 1 protein that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q9R1Y5-1

hypermethylated in cancer 1 protein isoform m1 (mouse)

mHIC1/iso:m1


"A hypermethylated in cancer 1 protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R1Y5-1." [PRO:DNx, UniProtKB:Q9R1Y5]


sequence



PR:000028779

hypermethylated in cancer 1 protein isoform 1

HIC1/iso:1


"A hypermethylated in cancer 1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14526-1 or a 1:1 ortholog thereof." [PMID:17283066, PRO:PD]


organism-sequence



PR:Q14526-1

hypermethylated in cancer 1 protein isoform 1 (human)

hHIC1/iso:1


"A hypermethylated in cancer 1 protein isoform 1 that is encoded in the genome of human." [PRO:PD]


sequence



PR:000028781

hypermethylated in cancer 1 protein isoform 2

HIC1/iso:2


"A hypermethylated in cancer 1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14526-2 or a 1:1 ortholog thereof." [PMID:17283066, PRO:PD]


organism-sequence



PR:Q14526-2

hypermethylated in cancer 1 protein isoform 2 (human)

hHIC1/iso:2


"A hypermethylated in cancer 1 protein isoform 2 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028784

hypermethylated in cancer 1 protein isoform 2 acetylated 1 (human)

hHIC1/iso:2/Ac:1


"A hypermethylated in cancer 1 protein isoform 2 acetylated 1 in human. Acetylation regulates transcriptional repression activity. UniProtKB:Q14526-2, Lys-314, MOD:00064." [PMID:17283066, PRO:PD]


modification



PR:000028783

hypermethylated in cancer 1 protein isoform 2 acetylated 1

HIC1/iso:2/Ac:1


"A hypermethylated in cancer 1 protein isoform 2 that has been acetylated on a Lys residue present in the YRWM/VKXEP motif situated within the central repression domain. Example: UniProtKB:Q14526-2, Lys-314, MOD:00064." [PMID:17283066, PRO:PD]


organism-modification



PR:000028784

hypermethylated in cancer 1 protein isoform 2 acetylated 1 (human)

hHIC1/iso:2/Ac:1


"A hypermethylated in cancer 1 protein isoform 2 acetylated 1 in human. Acetylation regulates transcriptional repression activity. UniProtKB:Q14526-2, Lys-314, MOD:00064." [PMID:17283066, PRO:PD]