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Protein Ontology report - eukaryotic-type lysine--tRNA ligase
PR:000009241 - http://purl.obolibrary.org/obo/PR_000009241
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000009241   
  PRO nameeukaryotic-type lysine--tRNA ligase 
  Synonyms
PRO-Short-label: EXACT:KARS1
Gene-based: RELATED:KARS | KIAA0070
Other: EXACT:eukaryotic lysyl-tRNA synthetase | lysyl-tRNA synthetase
  Definition"A protein that is a translation product of the human KARS1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification1                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000009241

eukaryotic-type lysine--tRNA ligase

KARS1


"A protein that is a translation product of the human KARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P15180

lysine--tRNA ligase, cytoplasmic (yeast)

yKARS


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of yeast." [OMA:P15180, PRO:DNx]


organism-gene



PR:Q15046

lysine--tRNA ligase (human)

hKARS1


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15046]


organism-sequence



PR:Q15046-1

lysine--tRNA ligase isoform Cytoplasmic (human)

hKARS1/iso:Cytoplasmic


"A lysine--tRNA ligase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15046-1." [PRO:DNx, UniProtKB:Q15046]


organism-sequence



PR:Q15046-2

lysine--tRNA ligase isoform Mitochondrial (human)

hKARS1/iso:Mitochondrial


"A lysine--tRNA ligase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15046-2." [PRO:DNx, UniProtKB:Q15046]


organism-modification



PR:000027320

lysine--tRNA ligase, initiator methionine removed form (human)

hKARS/InitMet-


"A eukaryotic-type lysine--tRNA ligase, initiator methionine removed form in human. Example: UniProtKB:Q15046-1, 2-597." [PRO:DNx]


Yes
organism-modification



PR:000045936

lysine--tRNA ligase phosphorylated 1 (human)

hKARS/Phos:1


"A lysine--tRNA ligase (human) that has been phosphorylated on the residue at the position equivalent to Ser-207 of the amino acid sequence represented by UniProtKB:Q15046-1. Example: UniProtKB:Q15046-1, Ser-207, MOD:00046." [iPTMnet:Q15046, PMID:19524539]


organism-modification



PR:000070306

lysine--tRNA ligase cysteinylated 1 (human)

hKARS1/Cyst:1


"A lysine--tRNA ligase (human) that has been cysteinylated on the residue at the position equivalent to Cys-456 of the amino acid sequence represented by UniProtKB:Q15046-1. Example: UniProtKB:Q15046-1, Cys-456, MOD:00765." [IEDB_epitope:1014566, IEDB_epitope:1569449, PRO:DNx]


organism-modification



PR:000073955

lysine--tRNA ligase deaminated 1 (human)

hKARS1/Deam:1


"A lysine--tRNA ligase (human) that has been deaminated on the residue at the position equivalent to Asn-90 of the amino acid sequence represented by UniProtKB:Q15046-1. Example: UniProtKB:Q15046-1, Asn-90, MOD:00684." [IEDB_epitope:690903, PRO:DNx]


organism-modification



PR:000075032

lysine--tRNA ligase methylated 1 (human)

hKARS1/Me:1


"A lysine--tRNA ligase (human) that has been methylated on the residue at the position equivalent to Cys-463 of the amino acid sequence represented by UniProtKB:Q15046-1. Example: UniProtKB:Q15046-1, Cys-463, MOD:00660." [IEDB_epitope:1011888, PRO:DNx]


organism-modification



PR:000076365

lysine--tRNA ligase deaminated 2 (human)

hKARS1/Deam:2


"A lysine--tRNA ligase (human) that has been deaminated on the residue at the position equivalent to Asn-21 of the amino acid sequence represented by UniProtKB:Q15046-1. Example: UniProtKB:Q15046-1, Asn-21, MOD:00684." [IEDB_epitope:1358961, PRO:DNx]


organism-gene



PR:Q22099

lysine--tRNA ligase (worm)

KARS1 (worm)


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of worm." [OMA:Q22099, PRO:DNx]


organism-gene



PR:Q5XIM7

lysine--tRNA ligase (rat)

rKARS1


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of rat." [OMA:Q5XIM7, PRO:DNx]


organism-gene



PR:Q99MN1

lysine--tRNA ligase (mouse)

mKARS1


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of mouse." [OMA:Q99MN1, PRO:DNx]


organism-gene



PR:Q9UUE6

lysine--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-)

Spom972h-KARS


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9UUE6, PRO:DNx]


organism-gene



PR:Q9ZPI1

lysine--tRNA ligase, cytoplasmic (Arabidopsis thaliana)

At-KARS


"A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9ZPI1, PRO:DNx]


modification



PR:000020366

eukaryotic-type lysine--tRNA ligase, initiator methionine removed form

KARS/InitMet-


"A eukaryotic-type lysine--tRNA ligase that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000027320

lysine--tRNA ligase, initiator methionine removed form (human)

hKARS/InitMet-


"A eukaryotic-type lysine--tRNA ligase, initiator methionine removed form in human. Example: UniProtKB:Q15046-1, 2-597." [PRO:DNx]


Yes
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KARS1 forms found in complexes   

KARS1 Component
Complexes
PR:000027320 hKARS/InitMet- PR:000027407 aminoacyl-tRNA synthetase multienzyme complex (human)