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Protein Ontology report - mannan-binding lectin serine protease 2
PR:000010194 - http://purl.obolibrary.org/obo/PR_000010194
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010194   
  PRO namemannan-binding lectin serine protease 2 
  Synonyms
PRO-Short-label: EXACT:MASP2
Other: EXACT:mannose-binding protein-associated serine protease 2 | MASP-2 | MBL-associated serine protease 2
  Definition"A protein that is a translation product of the human MASP2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
gene


PR:000010194 mannan-binding lectin serine protease 2
MASP2

organism-gene


PR:O00187 mannan-binding lectin serine protease 2 (human)
hMASP2

organism-sequence


PR:O00187-1 mannan-binding lectin serine protease 2 isoform 1 (human)
hMASP2/iso:1

organism-modification


PR:000064532 mannan-binding lectin serine protease 2 isoform 1, signal peptide removed form (human)
hMASP2/iso:1/SigPep-

organism-sequence


PR:O00187-2 mannan-binding lectin serine protease 2 isoform 2 (human)
hMASP2/iso:2

organism-gene


PR:Q91WP0 mannan-binding lectin serine protease 2 (mouse)
mMASP2

organism-sequence


PR:Q91WP0-1 mannan-binding lectin serine protease 2 isoform 1 (mouse)
mMASP2/iso:1
Yes
organism-sequence


PR:Q91WP0-2 mannan-binding lectin serine protease 2 isoform 2 (mouse)
mMASP2/iso:2
Yes
organism-gene


PR:Q9JJS8 mannan-binding lectin serine protease 2 (rat)
rMASP2

organism-sequence


PR:Q9JJS8-1 mannan-binding lectin serine protease 2 isoform r1 (rat)
rMASP2/iso:r1

organism-sequence


PR:Q9JJS8-2 mannan-binding lectin serine protease 2 isoform r2 (rat)
rMASP2/iso:r2

sequence


PR:000037130 mannan-binding lectin serine protease 2 isoform 1
MASP2/iso:1

organism-sequence


PR:O00187-1 mannan-binding lectin serine protease 2 isoform 1 (human)
hMASP2/iso:1

organism-modification


PR:000064532 mannan-binding lectin serine protease 2 isoform 1, signal peptide removed form (human)
hMASP2/iso:1/SigPep-

organism-sequence


PR:Q91WP0-1 mannan-binding lectin serine protease 2 isoform 1 (mouse)
mMASP2/iso:1
Yes
sequence


PR:000037133 mannan-binding lectin serine protease 2 isoform 2
MASP2/iso:2

organism-sequence


PR:O00187-2 mannan-binding lectin serine protease 2 isoform 2 (human)
hMASP2/iso:2

organism-sequence


PR:Q91WP0-2 mannan-binding lectin serine protease 2 isoform 2 (mouse)
mMASP2/iso:2
Yes
modification


PR:000020544 mannan-binding lectin serine protease 2 proteolytic cleavage product
MASP2/ClvPrd

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q91WP0-1 mMASP2/iso:1 acts_upstream_of_or_withinGO:0001867 complement activation, lectin pathway MGI_ref:5473786; PMID:16328467
enablesGO:0005515 protein binding with PR:O70165-1 MGI_ref:5473786; PMID:16328467
PR:Q91WP0-2 mMASP2/iso:2
This form is shorter than isoform 1, differs in sequence at positions 182-185, and lacks residues 186 to 685		 enablesGO:0005515 protein binding with PR:O70165-1 MGI_ref:5473786; PMID:16328467