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Protein Ontology report - protein Mdm4

PR:000010268 - http://purl.obolibrary.org/obo/PR_000010268

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000010268

PRO name

protein Mdm4

Synonyms

PRO-Short-label:	EXACT:	MDM4
Gene-based:	RELATED:	MDMX
Other:	EXACT:	double minute 4 protein \| mdm2-like p53-binding protein \| p53-binding protein Mdm4 \| protein Mdmx

Definition

"A protein that is a translation product of the human MDM4 gene or a 1:1 ortholog thereof." [PRO:DNx]

PRO Category

gene

Parent

PR:000000001 protein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	4
Sequence	2	Organism-Sequence	11
Modification	1	Organism-Modification	8

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

gene

PR:000010268 protein Mdm4

MDM4

organism-gene

PR:O15151 protein Mdm4 (human)

hMDM4

organism-sequence

PR:O15151-1 protein Mdm4 isoform 1 (human)

hMDM4/iso:1

organism-modification

PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)

hMDM4/iso:1/PhosUbiq:1

Yes

organism-sequence

PR:O15151-2 protein Mdm4 isoform 2 (human)

hMDM4/iso:2

organism-sequence

PR:O15151-3 protein Mdm4 isoform h3 (human)

hMDM4/iso:h3

organism-sequence

PR:O15151-4 protein Mdm4 isoform hHDMX211 (human)

hMDM4/iso:hHDMX211

organism-sequence

PR:O15151-5 protein Mdm4 isoform h5 (human)

hMDM4/iso:h5

organism-modification

PR:000045578 protein Mdm4 phosphorylated 1 (human)

hMDM4/Phos:1

organism-modification

PR:000048361 protein Mdm4 phosphorylated 2 (human)

hMDM4/Phos:2

organism-modification

PR:000048362 protein Mdm4 phosphorylated 3 (human)

hMDM4/Phos:3

organism-modification

PR:000048363 protein Mdm4 ubiquitinated form (human)

hMDM4/UbiqLys+

organism-modification

PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)

hMDM4/iso:1/PhosUbiq:1

Yes

organism-modification

PR:000064855 protein Mdm4 phosphorylated and ubiquitinated 1 (human)

hMDM4/PhosUbiq:1

organism-modification

PR:000075564 protein Mdm4 methylated 1 (human)

hMDM4/Me:1

organism-modification

PR:000084138 protein Mdm4 phosphorylated 4 (human)

hMDM4/Phos:4

organism-gene

PR:O35618 protein Mdm4 (mouse)

mMDM4

organism-sequence

PR:O35618-1 protein Mdm4 isoform Long (mouse)

mMDM4/iso:Long

organism-sequence

PR:O35618-2 protein Mdm4 isoform Short (mouse)

mMDM4/iso:Short

organism-sequence

PR:Q99L86 protein Mdm4 isoform 1 (mouse)

mMDM4/iso:1

organism-gene

PR:Q5XIN1 protein Mdm4 (rat)

rMDM4

organism-sequence

PR:Q5XIN1-1 protein Mdm4 isoform 1 (rat)

rMDM4/iso:1

organism-gene

PR:Q7ZUW7 protein Mdm4 (zebrafish)

z-MDM4

organism-sequence

PR:Q7ZUW7-1 protein Mdm4 isoform 1 (zebrafish)

z-MDM4/iso:1

organism-sequence

PR:Q7ZUW7-2 protein Mdm4 isoform 2 (zebrafish)

z-MDM4/iso:2

sequence

PR:000025835 protein Mdm4 isoform 1

MDM4/iso:1

organism-sequence

PR:O15151-1 protein Mdm4 isoform 1 (human)

hMDM4/iso:1

organism-modification

PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)

hMDM4/iso:1/PhosUbiq:1

Yes

organism-sequence

PR:Q5XIN1-1 protein Mdm4 isoform 1 (rat)

rMDM4/iso:1

organism-sequence

PR:Q99L86 protein Mdm4 isoform 1 (mouse)

mMDM4/iso:1

modification

PR:000025836 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1

MDM4/iso:1/PhosUbiq:1

organism-modification

PR:000025837 protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)

hMDM4/iso:1/PhosUbiq:1

Yes

sequence

PR:000038047 protein Mdm4 isoform 2

MDM4/iso:2

organism-sequence

PR:O15151-2 protein Mdm4 isoform 2 (human)

hMDM4/iso:2

organism-sequence

PR:O35618-2 protein Mdm4 isoform Short (mouse)

mMDM4/iso:Short

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Functional Annotation (GO-centric view)

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Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511560
Molecular Function GO Term	Protein Forms & Complexes	Evidence
GO:0071889 14-3-3 protein binding	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511572
Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005634 nucleus	PR:000025837 hMDM4/iso:1/PhosUbiq:1	PMID:16511560