back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - mediator of RNA polymerase II transcription subunit 14
PR:000010286 - http://purl.obolibrary.org/obo/PR_000010286
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010286   
  PRO namemediator of RNA polymerase II transcription subunit 14 
  Synonyms
PRO-Short-label: EXACT:MED14
Gene-based: RELATED:ARC150 | CXorf4 | DRIP150 | EXLM1 | Gm641 | RGR1 | TRAP170
Other: EXACT:activator-recruited cofactor 150 kDa component | cofactor required for Sp1 transcriptional activation subunit 2 | CRSP complex subunit 2 | mediator complex subunit 14 | thyroid hormone receptor-associated protein complex 170 kDa component | transcriptional coactivator CRSP150 | Trap170 | vitamin D3 receptor-interacting protein complex 150 kDa component
RELATED:Crsp2
  Definition"A protein that is a translation product of the human MED14 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence3                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000010286

mediator of RNA polymerase II transcription subunit 14

MED14


"A protein that is a translation product of the human MED14 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A2ABV5

mediator of RNA polymerase II transcription subunit 14 (mouse)

mMED14


"A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of mouse." [OMA:A2ABV5, PRO:DNx]


organism-sequence



PR:A2ABV5-1

mediator of RNA polymerase II transcription subunit 14 isoform 1 (mouse)

mMED14/iso:1


"A mediator of RNA polymerase II transcription subunit 14 isoform 1 that is encoded in the genome of mouse." [PRO:HJD, RefSeq:NP_001041673]

Yes

Yes
organism-sequence



PR:A2ABV5-2

mediator of RNA polymerase II transcription subunit 14 isoform 2 (mouse)

mMED14/iso:2


"A mediator of RNA polymerase II transcription subunit 14 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:A2ABV5-3

mediator of RNA polymerase II transcription subunit 14 isoform 3 (mouse)

mMED14/iso:3


"A mediator of RNA polymerase II transcription subunit 14 isoform 3 that is encoded in the genome of mouse." [PMID:10512684, PRO:HJD]


organism-sequence



PR:A2ABV5-4

mediator of RNA polymerase II transcription subunit 14 isoform m4 (mouse)

mMED14/iso:m4


"A mediator of RNA polymerase II transcription subunit 14 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2ABV5-4." [PRO:DNx, UniProtKB:A2ABV5]


organism-gene



PR:O60244

mediator of RNA polymerase II transcription subunit 14 (human)

hMED14


"A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60244]


organism-sequence



PR:O60244-1

mediator of RNA polymerase II transcription subunit 14 isoform 1 (human)

hMED14/iso:1


"A mediator of RNA polymerase II transcription subunit 14 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-modification



PR:000069122

mediator of RNA polymerase II transcription subunit 14 methylated 1 (human)

hMED14/Me:1


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been methylated on the residue at the position equivalent to Cys-779 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-779, MOD:00660." [IEDB_epitope:1043652, PRO:DNx]


organism-modification



PR:000077063

mediator of RNA polymerase II transcription subunit 14 methylated 2 (human)

hMED14/Me:2


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been methylated on the residue at the position equivalent to Cys-903 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-903, MOD:00660." [IEDB_epitope:1046246, PRO:DNx]


organism-modification



PR:000078182

mediator of RNA polymerase II transcription subunit 14 methylated 3 (human)

hMED14/Me:3


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been methylated on the residue at the position equivalent to Cys-708 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-708, MOD:00660." [IEDB_epitope:1049926, PRO:DNx]


organism-modification



PR:000079999

mediator of RNA polymerase II transcription subunit 14 methylated 4 (human)

hMED14/Me:4


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been methylated on the residue at the position equivalent to Cys-635 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-635, MOD:00660." [IEDB_epitope:1014827, PRO:DNx]


organism-modification



PR:000080119

mediator of RNA polymerase II transcription subunit 14 cysteinylated 1 (human)

hMED14/Cyst:1


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been cysteinylated on the residue at the position equivalent to Cys-779 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-779, MOD:00765." [IEDB_epitope:1043651, PRO:DNx]


organism-modification



PR:000081758

mediator of RNA polymerase II transcription subunit 14 methylated 5 (human)

hMED14/Me:5


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been methylated on the residue at the position equivalent to Cys-334 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-334, MOD:00660." [IEDB_epitope:1009058, IEDB_epitope:1061254, PRO:DNx]


organism-modification



PR:000081973

mediator of RNA polymerase II transcription subunit 14 methylated 6 (human)

hMED14/Me:6


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been methylated on the residue at the position equivalent to Cys-1316 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-1316, MOD:00660." [IEDB_epitope:1040348, PRO:DNx]


organism-modification



PR:000084756

mediator of RNA polymerase II transcription subunit 14 phosphorylated 1 (human)

hMED14/Phos:1


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been phosphorylated on the residue at the position equivalent to Ser-481 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Ser-481, MOD:00046." [IEDB_epitope:2149220, PRO:DNx]


organism-modification



PR:000085040

mediator of RNA polymerase II transcription subunit 14 cysteinylated 2 (human)

hMED14/Cyst:2


"A mediator of RNA polymerase II transcription subunit 14 (human) that has been cysteinylated on the residue at the position equivalent to Cys-708 of the amino acid sequence represented by UniProtKB:O60244. UniProtKB:O60244, Cys-708, MOD:00765." [IEDB_epitope:637083, PRO:DNx]


organism-gene



PR:Q03570

mediator of RNA polymerase II transcription subunit 14 (worm)

MED14 (worm)


"A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of worm." [PANTHER:PTHR12809:SF2, PRO:DNx]


organism-sequence



PR:Q03570-1

mediator of RNA polymerase II transcription subunit 14 isoform b (worm)

MED14/iso:b (worm)


"A mediator of RNA polymerase II transcription subunit 14 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03570-1." [PRO:DNx, UniProtKB:Q03570]


organism-sequence



PR:Q03570-2

mediator of RNA polymerase II transcription subunit 14 isoform a (worm)

MED14/iso:a (worm)


"A mediator of RNA polymerase II transcription subunit 14 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03570-2." [PRO:DNx, UniProtKB:Q03570]


organism-sequence



PR:Q03570-3

mediator of RNA polymerase II transcription subunit 14 isoform c (worm)

MED14/iso:c (worm)


"A mediator of RNA polymerase II transcription subunit 14 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03570-3." [PRO:DNx, UniProtKB:Q03570]


organism-gene



PR:Q9P7Y4

mediator of RNA polymerase II transcription subunit 14 (Schizosaccharomyces pombe 972h-)

Spom972h-MED14


"A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR12809:SF2, PRO:DNx]


organism-gene



PR:Q9SR02

mediator of RNA polymerase II transcription subunit 14 (Arabidopsis thaliana)

At-MED14


"A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of Arabidopsis thaliana." [PANTHER:PTHR12809:SF2, PRO:DNx]


organism-gene



PR:Q9W0P8

mediator of RNA polymerase II transcription subunit 14 (fruit fly)

fly-MED14


"A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of fruit fly." [OMA:Q9W0P8, PRO:DNx]


organism-sequence



PR:Q9W0P8-1

mediator of RNA polymerase II transcription subunit 14 isoform 1 (fruit fly)

fly-MED14/iso:1


"A mediator of RNA polymerase II transcription subunit 14 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9W0P8-1." [PRO:DNx, UniProtKB:Q9W0P8]


organism-sequence



PR:Q9W0P8-3

mediator of RNA polymerase II transcription subunit 14 isoform 2 (fruit fly)

fly-MED14/iso:2


"A mediator of RNA polymerase II transcription subunit 14 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9W0P8-3." [PRO:DNx, UniProtKB:Q9W0P8]


sequence



PR:000028892

mediator of RNA polymerase II transcription subunit 14 isoform 1

MED14/iso:1


"A mediator of RNA polymerase II transcription subunit 14 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2ABV5-1 or a 1:1 ortholog thereof." [PRO:HJD, RefSeq:NP_001041673]


organism-sequence



PR:A2ABV5-1

mediator of RNA polymerase II transcription subunit 14 isoform 1 (mouse)

mMED14/iso:1


"A mediator of RNA polymerase II transcription subunit 14 isoform 1 that is encoded in the genome of mouse." [PRO:HJD, RefSeq:NP_001041673]

Yes

Yes
organism-sequence



PR:O60244-1

mediator of RNA polymerase II transcription subunit 14 isoform 1 (human)

hMED14/iso:1


"A mediator of RNA polymerase II transcription subunit 14 isoform 1 that is encoded in the genome of human." [PRO:HJD]


sequence



PR:000028894

mediator of RNA polymerase II transcription subunit 14 isoform 2

MED14/iso:2


"A mediator of RNA polymerase II transcription subunit 14 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2ABV5-2 or a 1:1 ortholog thereof." [PMID:10512684, PRO:HJD]


organism-sequence



PR:A2ABV5-2

mediator of RNA polymerase II transcription subunit 14 isoform 2 (mouse)

mMED14/iso:2


"A mediator of RNA polymerase II transcription subunit 14 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]


sequence



PR:000028896

mediator of RNA polymerase II transcription subunit 14 isoform 3

MED14/iso:3


"A mediator of RNA polymerase II transcription subunit 14 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2ABV5-3 or a 1:1 ortholog thereof." [PMID:10512684, PRO:HJD]


organism-sequence



PR:A2ABV5-3

mediator of RNA polymerase II transcription subunit 14 isoform 3 (mouse)

mMED14/iso:3


"A mediator of RNA polymerase II transcription subunit 14 isoform 3 that is encoded in the genome of mouse." [PMID:10512684, PRO:HJD]


Back to top
MED14 forms found in complexes   

MED14 Component
Complexes
PR:A2ABV5ZDASHZ1 mMED14/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:A2ABV5-1 mMED14/iso:1 located_inGO:0016592 mediator complex MGI_ref:4462751; PMID:20508642