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Protein Ontology report - mediator of RNA polymerase II transcription subunit 15
PR:000010287 - http://purl.obolibrary.org/obo/PR_000010287
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000010287   
  PRO namemediator of RNA polymerase II transcription subunit 15 
  Synonyms
PRO-Short-label: EXACT:MED15
Gene-based: RELATED:ARC105 | CTG7A | PCQAP | TIG1 | TNRC7
Other: EXACT:activator-recruited cofactor 105 kDa component | CTG repeat protein 7a | mediator complex subunit 15 | PC2 glutamine/Q-rich-associated protein | positive cofactor 2 glutamine/Q-rich-associated protein | TIG-1 | TPA-inducible gene 1 protein | trinucleotide repeat-containing gene 7 protein
  Definition"A protein that is a translation product of the human MED15 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000010287

mediator of RNA polymerase II transcription subunit 15

MED15


"A protein that is a translation product of the human MED15 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q7ZVN7

mediator of RNA polymerase II transcription subunit 15 (zebrafish)

z-MED15


"A mediator of RNA polymerase II transcription subunit 15 that is encoded in the genome of zebrafish." [OMA:Q7ZVN7, PRO:DNx]


organism-gene



PR:Q924H2

mediator of RNA polymerase II transcription subunit 15 (mouse)

mMED15


"A mediator of RNA polymerase II transcription subunit 15 that is encoded in the genome of mouse." [OMA:Q924H2, PRO:DAN]


organism-sequence



PR:Q924H2-1

mediator of RNA polymerase II transcription subunit 15 isoform 1 (mouse)

mMED15/iso:1


"A mediator of RNA polymerase II transcription subunit 15 isoform 1 that is encoded in the genome of mouse." [PMID:12040188, PRO:HJD]

Yes

Yes
organism-gene



PR:Q96RN5

mediator of RNA polymerase II transcription subunit 15 (human)

hMED15


"A mediator of RNA polymerase II transcription subunit 15 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96RN5]


organism-sequence



PR:Q96RN5-1

mediator of RNA polymerase II transcription subunit 15 isoform h1 (human)

hMED15/iso:h1


"A mediator of RNA polymerase II transcription subunit 15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96RN5-1." [PRO:DNx, UniProtKB:Q96RN5]


organism-sequence



PR:Q96RN5-2

mediator of RNA polymerase II transcription subunit 15 isoform h2 (human)

hMED15/iso:h2


"A mediator of RNA polymerase II transcription subunit 15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96RN5-2." [PRO:DNx, UniProtKB:Q96RN5]


organism-sequence



PR:Q96RN5-3

mediator of RNA polymerase II transcription subunit 15 isoform h3 (human)

hMED15/iso:h3


"A mediator of RNA polymerase II transcription subunit 15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96RN5-3." [PRO:DNx, UniProtKB:Q96RN5]


organism-modification



PR:000079949

mediator of RNA polymerase II transcription subunit 15 deaminated 1 (human)

hMED15/Deam:1


"A mediator of RNA polymerase II transcription subunit 15 (human) that has been deaminated on the residue at the position equivalent to Asn-701 of the amino acid sequence represented by UniProtKB:Q96RN5-1. Example: UniProtKB:Q96RN5-1, Asn-701, MOD:00684." [IEDB_epitope:1995557, PRO:DNx]


organism-modification



PR:000084741

mediator of RNA polymerase II transcription subunit 15 deaminated 2 (human)

hMED15/Deam:2


"A mediator of RNA polymerase II transcription subunit 15 (human) that has been deaminated on the residue at the position equivalent to Gln-337 of the amino acid sequence represented by UniProtKB:Q96RN5-1. Example: UniProtKB:Q96RN5-1, Gln-337, MOD:00685." [IEDB_epitope:1366759, PRO:DNx]


organism-gene



PR:Q9Y149

mediator of RNA polymerase II transcription subunit 15 (fruit fly)

fly-MED15


"A mediator of RNA polymerase II transcription subunit 15 that is encoded in the genome of fruit fly." [OMA:Q9Y149, PRO:DNx]


sequence



PR:000028878

mediator of RNA polymerase II transcription subunit 15 isoform 1

MED15/iso:1


"A mediator of RNA polymerase II transcription subunit 15 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q924H2-1 or a 1:1 ortholog thereof." [PMID:12040188, PRO:HJD]


organism-sequence



PR:Q924H2-1

mediator of RNA polymerase II transcription subunit 15 isoform 1 (mouse)

mMED15/iso:1


"A mediator of RNA polymerase II transcription subunit 15 isoform 1 that is encoded in the genome of mouse." [PMID:12040188, PRO:HJD]

Yes

Yes
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MED15 forms found in complexes   

MED15 Component
Complexes
PR:Q924H2ZDASHZ1 mMED15/iso:1 PR:000028902 mediator complex, MED26-containing (mouse)
PR:000028957 mediator complex, CDK8-containing (mouse)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0016592 mediator complexPR:Q924H2-1 mMED15/iso:1 MGI_ref:4462751; PMID:20508642