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Protein Ontology report - kinetochore protein NDC80
PR:000011050 - http://purl.obolibrary.org/obo/PR_000011050
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000011050   
  PRO namekinetochore protein NDC80 
  Synonyms
PRO-Short-label: EXACT:NDC80
Gene-based: RELATED:HEC | HEC1 | KNTC2
Other: EXACT:Hec1 | highly expressed in cancer protein | kinetochore protein Hec1 | kinetochore-associated protein 2 | retinoblastoma-associated protein HEC
  Definition"A protein that is a translation product of the human NDC80 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 9                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000011050

kinetochore protein NDC80

NDC80


"A protein that is a translation product of the human NDC80 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O14777

kinetochore protein NDC80 (human)

hNDC80


"A kinetochore protein NDC80 that is encoded in the genome of human." [PMID:17785528, PMID:20624902, PRO:KER]

Yes

organism-sequence



PR:O14777-1

kinetochore protein NDC80 homolog isoform 1 (human)

hNDC80/iso:1


"A kinetochore protein NDC80 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045569

kinetochore protein NDC80 phosphorylated 1 (human)

hNDC80/Phos:1


"A kinetochore protein NDC80 (human) that has been phosphorylated at Ser-165. UniProtKB:O14777, Ser-165, MOD:00046." [iPTMnet:O14777, PMID:18297113, PMID:21832156]


organism-modification



PR:000066076

kinetochore protein NDC80 deaminated 1 (human)

hNDC80/Deam:1


"A kinetochore protein NDC80 (human) that has been deaminated on the residue at the position equivalent to Asn-332 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Asn-332, MOD:00684." [IEDB_epitope:2139875, PRO:DNx]


organism-modification



PR:000068345

kinetochore protein NDC80 deaminated 2 (human)

hNDC80/Deam:2


"A kinetochore protein NDC80 (human) that has been deaminated on the residue at the position equivalent to Asn-276 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Asn-276, MOD:00684." [IEDB_epitope:1348961, PRO:DNx]


organism-modification



PR:000069025

kinetochore protein NDC80 cysteinylated 1 (human)

hNDC80/Cyst:1


"A kinetochore protein NDC80 (human) that has been cysteinylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-191, MOD:00765." [IEDB_epitope:1563373, PRO:DNx]


organism-modification



PR:000072892

kinetochore protein NDC80 methylated 1 (human)

hNDC80/Me:1


"A kinetochore protein NDC80 (human) that has been methylated on the residue at the position equivalent to Cys-95 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-95, MOD:00660." [IEDB_epitope:1012009, PRO:DNx]


organism-modification



PR:000076086

kinetochore protein NDC80 phosphorylated 2 (human)

hNDC80/Phos:2


"A kinetochore protein NDC80 (human) that has been phosphorylated on the residue at the position equivalent to Thr-635 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Thr-635, MOD:00047." [IEDB_epitope:2146963, PRO:DNx]


organism-modification



PR:000078733

kinetochore protein NDC80 methylated 2 (human)

hNDC80/Me:2


"A kinetochore protein NDC80 (human) that has been methylated on the residue at the position equivalent to Cys-342 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-342, MOD:00660." [IEDB_epitope:1046533, PRO:DNx]


organism-modification



PR:000079460

kinetochore protein NDC80 cysteinylated 2 (human)

hNDC80/Cyst:2


"A kinetochore protein NDC80 (human) that has been cysteinylated on the residue at the position equivalent to Cys-449 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-449, MOD:00765." [IEDB_epitope:1582540, PRO:DNx]


organism-modification



PR:000083884

kinetochore protein NDC80 deaminated 3 (human)

hNDC80/Deam:3


"A kinetochore protein NDC80 (human) that has been deaminated on the residue at the position equivalent to Gln-278 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Gln-278, MOD:00685." [IEDB_epitope:1348962, PRO:DNx]


organism-modification



PR:000084178

kinetochore protein NDC80 phosphorylated 3 (human)

hNDC80/Phos:3


"A kinetochore protein NDC80 (human) that has been phosphorylated on the residue at the position equivalent to Thr-572 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Thr-572, MOD:00047." [IEDB_epitope:2149303, PRO:DNx]


organism-gene



PR:P40460

kinetochore protein NDC80 (yeast)

yNDC80


"A kinetochore protein NDC80 that is encoded in the genome of yeast." [OMA:P40460, PRO:DNx]


organism-gene



PR:Q10198

kinetochore protein ndc80 (Schizosaccharomyces pombe 972h-)

Spom972h-NDC80


"A kinetochore protein NDC80 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q10198, PRO:DNx]


organism-gene



PR:Q17635

kinetochore protein ndc-80 (worm)

NDC80 (worm)


"A kinetochore protein NDC80 that is encoded in the genome of worm." [OMA:Q17635, PRO:DNx]


organism-gene



PR:Q5A216

probable kinetochore protein NDC80 (Candida albicans SC5314)

Calb-NDC80


"A kinetochore protein NDC80 that is encoded in the genome of Candida albicans SC5314." [PRO:DAN]


organism-gene



PR:Q6DRJ7

kinetochore protein NDC80 homolog (zebrafish)

z-NDC80


"A kinetochore protein NDC80 that is encoded in the genome of zebrafish." [OMA:Q6DRJ7, PRO:DNx]


organism-gene



PR:Q76I89

kinetochore protein NDC80 homolog (chicken)

chick-NDC80


"A kinetochore protein NDC80 that is encoded in the genome of chicken." [OMA:Q76I89, PRO:DNx]


organism-gene



PR:Q9D0F1

kinetochore protein NDC80 homolog (mouse)

mNDC80


"A kinetochore protein NDC80 that is encoded in the genome of mouse." [OMA:Q9D0F1, PRO:DNx]


organism-sequence



PR:Q9D0F1-1

kinetochore protein NDC80 homolog isoform 1 (mouse)

mNDC80/iso:1


"A kinetochore protein NDC80 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q9M1G5

kinetochore protein NDC80 homolog (Arabidopsis thaliana)

At-NDC80


"A kinetochore protein NDC80 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9M1G5, PRO:DNx]


sequence



PR:000038002

kinetochore protein NDC80 isoform 1

NDC80/iso:1


"A kinetochore protein NDC80 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14777-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O14777-1

kinetochore protein NDC80 homolog isoform 1 (human)

hNDC80/iso:1


"A kinetochore protein NDC80 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q9D0F1-1

kinetochore protein NDC80 homolog isoform 1 (mouse)

mNDC80/iso:1


"A kinetochore protein NDC80 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O14777 hNDC80 acts_upstream_of_or_withinGO:0034501 protein localization to kinetochore PMID:17785528
enablesGO:0005515 protein binding with PR:Q8NG31 AF15q14 (human) BioGRID:BG-252640; IntAct:EBI-999882
GO:0005515 protein binding with PR:Q9BZD4 CDCA1 BioGRID:BG-252640; IntAct:EBI-999882
located_inGO:0000776 kinetochore PMID:20624902