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Protein Ontology report - N-glycosylase/DNA lyase
PR:000011616 - http://purl.obolibrary.org/obo/PR_000011616
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000011616   
  PRO nameN-glycosylase/DNA lyase 
  Synonyms
PRO-Short-label: EXACT:OGG1
Gene-based: RELATED:MMH | MUTM | OGH1
  Definition"A protein that is a translation product of the human OGG1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 22                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000011616

N-glycosylase/DNA lyase

OGG1


"A protein that is a translation product of the human OGG1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O08760

N-glycosylase/DNA lyase (mouse)

mOGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of mouse." [OMA:O08760, PRO:DNx]


organism-sequence



PR:O08760-1

N-glycosylase/DNA lyase isoform 1 (mouse)

mOGG1/iso:1


"An N-glycosylase/DNA lyase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:O15527

N-glycosylase/DNA lyase (human)

hOGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:000060588

N-glycosylase/DNA lyase sequence variant D268A (human)

hOGG1/var:D268A


"An N-glycosylase/DNA lyase (human) that has an Ala residue at the position equivalent to Asp-268 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Asp-268, CHEBI:46217." [PRO:DNx, Reactome:R-HSA-9663727]


organism-sequence



PR:000060900

N-glycosylase/DNA lyase sequence variant R46L (human)

hOGG1/var:R46L


"An N-glycosylase/DNA lyase (human) that has a Leu residue at the position equivalent to Arg-46 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Arg-46, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-9657128]


organism-sequence



PR:000061274

N-glycosylase/DNA lyase sequence variant R131Q (human)

hOGG1/var:R131Q


"An N-glycosylase/DNA lyase (human) that has a Gln residue at the position equivalent to Arg-131 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Arg-131, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-9658752]


organism-sequence



PR:000061617

N-glycosylase/DNA lyase sequence variant R46Q (human)

hOGG1/var:R46Q


"An N-glycosylase/DNA lyase (human) that has a Gln residue at the position equivalent to Arg-46 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Arg-46, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-9657113]


organism-sequence



PR:000061641

N-glycosylase/DNA lyase sequence variant S326C (human)

hOGG1/var:S326C


"An N-glycosylase/DNA lyase (human) that has a Cys residue at the position equivalent to Ser-326 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Ser-326, CHEBI:29950." [PRO:DNx, Reactome:R-HSA-9658769]


organism-sequence



PR:000062126

N-glycosylase/DNA lyase sequence variant R229Q (human)

hOGG1/var:R229Q


"An N-glycosylase/DNA lyase (human) that has a Gln residue at the position equivalent to Arg-229 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Arg-229, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-9657082]


organism-sequence



PR:000062215

N-glycosylase/DNA lyase sequence variant A288V (human)

hOGG1/var:A288V


"An N-glycosylase/DNA lyase (human) that has a Val residue at the position equivalent to Ala-288 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Ala-288, CHEBI:30015." [PRO:DNx, Reactome:R-HSA-9656265]


organism-sequence



PR:000062372

N-glycosylase/DNA lyase sequence variant A53T (human)

hOGG1/var:A53T


"An N-glycosylase/DNA lyase (human) that has a Thr residue at the position equivalent to Ala-53 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Ala-53, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-9656270]


organism-sequence



PR:000062464

N-glycosylase/DNA lyase sequence variant R131G (human)

hOGG1/var:R131G


"An N-glycosylase/DNA lyase (human) that has a Gly residue at the position equivalent to Arg-131 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Arg-131, CHEBI:29947." [PRO:DNx, Reactome:R-HSA-9658754]


organism-sequence



PR:000063637

N-glycosylase/DNA lyase sequence variant K249Q (human)

hOGG1/var:K249Q


"An N-glycosylase/DNA lyase (human) that has a Gln residue at the position equivalent to Lys-249 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Lys-249, CHEBI:30011." [PRO:DNx, Reactome:R-HSA-9663725]


organism-sequence



PR:000063898

N-glycosylase/DNA lyase sequence variant D268N (human)

hOGG1/var:D268N


"An N-glycosylase/DNA lyase (human) that has an Asn residue at the position equivalent to Asp-268 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Asp-268, CHEBI:50347." [PRO:DNx, Reactome:R-HSA-9663721]


organism-sequence



PR:000064520

N-glycosylase/DNA lyase sequence variant R154H (human)

hOGG1/var:R154H


"An N-glycosylase/DNA lyase (human) that has a His residue at the position equivalent to Arg-154 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Arg-154, CHEBI:29979." [PRO:DNx, Reactome:R-HSA-9657145]


organism-sequence



PR:O15527-1

N-glycosylase/DNA lyase isoform 1 (human)

hOGG1/iso:1


"An N-glycosylase/DNA lyase isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000028600

N-glycosylase/DNA lyase isoform 1 acetylated 1 (human)

hOGG1/iso:1/Ac:1


"An N-glycosylase/DNA lyase isoform 1 acetylated 1 in human. UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064." [KAT:O15527, PMID:16478987, PRO:PD]

Yes

organism-sequence



PR:O15527-2

N-glycosylase/DNA lyase isoform h1B (human)

hOGG1/iso:h1B


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-2." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:O15527-3

N-glycosylase/DNA lyase isoform h1C (human)

hOGG1/iso:h1C


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-3." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:O15527-4

N-glycosylase/DNA lyase isoform h2A (human)

hOGG1/iso:h2A


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-4." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:000061113

N-glycosylase/DNA lyase isoform h2A sequence variant G12E (human)

hOGG1/iso:h2A/var:G12E


"An N-glycosylase/DNA lyase isoform h2A (human) that has a Glu residue at the position equivalent to Gly-12 of the amino acid sequence represented by UniProtKB:O15527-4. UniProtKB:O15527-4, Gly-12, CHEBI:29972." [PRO:DNx, Reactome:R-HSA-9657042]


organism-sequence



PR:O15527-5

N-glycosylase/DNA lyase isoform h2B (human)

hOGG1/iso:h2B


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-5." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:O15527-6

N-glycosylase/DNA lyase isoform h2C (human)

hOGG1/iso:h2C


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-6." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:O15527-7

N-glycosylase/DNA lyase isoform h2D (human)

hOGG1/iso:h2D


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-7." [PRO:DNx, UniProtKB:O15527]


organism-sequence



PR:O15527-8

N-glycosylase/DNA lyase isoform h2E (human)

hOGG1/iso:h2E


"An N-glycosylase/DNA lyase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-8." [PRO:DNx, UniProtKB:O15527]


organism-modification



PR:000081444

N-glycosylase/DNA lyase deaminated 1 (human)

hOGG1/Deam:1


"An N-glycosylase/DNA lyase (human) that has been deaminated on the residue at the position equivalent to Gln-325 of the amino acid sequence represented by UniProtKB:O15527-1. Example: UniProtKB:O15527-1, Gln-325, MOD:00685." [IEDB_epitope:1993694, PRO:DNx]


organism-gene



PR:O70249

N-glycosylase/DNA lyase (rat)

rOGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of rat." [OMA:O70249, PRO:DNx]


organism-gene



PR:P53397

N-glycosylase/DNA lyase (yeast)

yOGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of yeast." [PRO:DNx]


organism-gene



PR:Q54CZ3

uncharacterized protein, ogg1 translation product (Dictyostelium discoideum)

Dicty-OGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of Dictyostelium discoideum." [PANTHER:PTHR10242:SF0, PRO:DNx]


organism-gene



PR:Q9FNY7

N-glycosylase/DNA lyase OGG1 (Arabidopsis thaliana)

At-OGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9FNY7, PRO:DNx]


organism-gene



PR:Q9V3I8

N-glycosylase/DNA lyase (fruit fly)

fly-OGG1


"An N-glycosylase/DNA lyase that is encoded in the genome of fruit fly." [OMA:Q9V3I8, PRO:DNx]


sequence



PR:000028597

N-glycosylase/DNA lyase isoform 1

OGG1/iso:1


"An N-glycosylase/DNA lyase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15527-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:O08760-1

N-glycosylase/DNA lyase isoform 1 (mouse)

mOGG1/iso:1


"An N-glycosylase/DNA lyase isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:O15527-1

N-glycosylase/DNA lyase isoform 1 (human)

hOGG1/iso:1


"An N-glycosylase/DNA lyase isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000028600

N-glycosylase/DNA lyase isoform 1 acetylated 1 (human)

hOGG1/iso:1/Ac:1


"An N-glycosylase/DNA lyase isoform 1 acetylated 1 in human. UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064." [KAT:O15527, PMID:16478987, PRO:PD]

Yes

modification



PR:000028599

N-glycosylase/DNA lyase isoform 1 acetylated 1

OGG1/iso:1/Ac:1


"An N-glycosylase/DNA lyase isoform 1 that is acetylated on the conserved Lys residues (positions 3 and 6) within the R[RK]KGSK motif located at the C-terminus. Example: UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064." [KAT:O15527, PMID:16478987, PRO:PD]


organism-modification



PR:000028600

N-glycosylase/DNA lyase isoform 1 acetylated 1 (human)

hOGG1/iso:1/Ac:1


"An N-glycosylase/DNA lyase isoform 1 acetylated 1 in human. UniProtKB:O15527-1, Lys-338/Lys-341, MOD:00064." [KAT:O15527, PMID:16478987, PRO:PD]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:000028600 hOGG1/iso:1/Ac:1 PMID:16478987