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Protein Ontology report - paired box protein Pax-6
PR:000012318 - http://purl.obolibrary.org/obo/PR_000012318
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000012318   
  PRO namepaired box protein Pax-6 
  Synonyms
PRO-Short-label: EXACT:PAX6
Gene-based: RELATED:AN2 | Pax-6 | Sey
Other: EXACT:aniridia type II protein | oculorhombin
  Definition"A paired box protein PAX group IV that is a translation product of the human PAX6 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000037798 paired box protein PAX group IV
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence3                                                  Organism-Sequence 13                                        
         Modification2                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000012318

paired box protein Pax-6

PAX6


"A paired box protein PAX group IV that is a translation product of the human PAX6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O18381

paired box protein Pax-6 (fruit fly)

fly-PAX6


"A paired box protein Pax-6 that is encoded in the genome of fruit fly." [PANTHER:PTHR24329:SF73, PRO:DNx]


organism-sequence



PR:O18381-1

paired box protein Pax-6 isoform Larval (fruit fly)

fly-PAX6/iso:Larval


"A paired box protein Pax-6 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O18381-1." [PRO:DNx, UniProtKB:O18381]


organism-sequence



PR:O18381-2

paired box protein Pax-6 isoform Embryonic (fruit fly)

fly-PAX6/iso:Embryonic


"A paired box protein Pax-6 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O18381-2." [PRO:DNx, UniProtKB:O18381]


organism-sequence



PR:O18381-3

paired box protein Pax-6 isoform B (fruit fly)

fly-PAX6/iso:B


"A paired box protein Pax-6 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O18381-3." [PRO:DNx, UniProtKB:O18381]


organism-gene



PR:P26367

paired box protein Pax-6 (human)

hPAX6


"A paired box protein Pax-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P26367]


organism-sequence



PR:P26367-1

paired box protein Pax-6 isoform 1 (human)

hPAX6/iso:1


"A paired box protein Pax-6 isoform 1 that is encoded in the genome of human." [PMID:7958875, PRO:CNA]


organism-sequence



PR:P26367-2

paired box protein Pax-6 isoform 2 (human)

hPAX6/iso:2


"A paired box protein Pax-6 isoform 2 that is encoded in the genome of human." [PMID:10954416, PMID:7958875, PRO:CNA]


organism-sequence



PR:P26367-3

paired box protein Pax-6 isoform h3 (human)

hPAX6/iso:h3


"A paired box protein Pax-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26367-3." [PRO:DNx, UniProtKB:P26367]


organism-modification



PR:000065578

paired box protein Pax-6 deaminated 1 (human)

hPAX6/Deam:1


"A paired box protein Pax-6 (human) that has been deaminated on the residue at the position equivalent to Asn-114 of the amino acid sequence represented by UniProtKB:P26367-1. Example: UniProtKB:P26367-1, Asn-114, MOD:00684." [IEDB_epitope:1975896, PRO:DNx]


organism-gene



PR:P26630

paired box protein Pax-6 (zebrafish)

z-PAX6


"A paired box protein Pax-6 that is encoded in the genome of zebrafish." [OMA:P26630, PRO:DNx]


organism-sequence



PR:P26630-1

paired box protein Pax-6 isoform Short (zebrafish)

z-PAX6/iso:Short


"A paired box protein Pax-6 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26630-1." [PRO:DNx, UniProtKB:P26630]


organism-sequence



PR:P26630-2

paired box protein Pax-6 isoform Long (zebrafish)

z-PAX6/iso:Long


"A paired box protein Pax-6 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26630-2." [PRO:DNx, UniProtKB:P26630]


organism-gene



PR:P63015

paired box protein Pax-6 (mouse)

mPAX6


"A paired box protein Pax-6 that is encoded in the genome of mouse." [OMA:P63015, PRO:DNx]


organism-sequence



PR:P63015-1

paired box protein Pax-6 isoform 1 (mouse)

mPAX6/iso:1


"A paired box protein Pax-6 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PMID:21084637, PRO:HJD]

Yes

organism-sequence



PR:P63015-2

paired box protein Pax-6 isoform 2 (mouse)

mPAX6/iso:2


"A paired box protein Pax-6 isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PMID:21084637, PRO:HJD]


organism-sequence



PR:P63015-3

paired box protein Pax-6 isoform 3 (mouse)

mPAX6/iso:3


"A paired box protein Pax-6 isoform 3 that is encoded in the genome of mouse." [PMID:15489334, PMID:21084637, PRO:HJD]


organism-modification



PR:000037287

paired box protein Pax-6 isoform 3 sumoylated 1 (mouse)

mPAX6/iso:3/Sumo:1


"A paired box protein Pax-6 isoform 3 sumoylated 1 in mouse. UniProtKB:P63015-3, Lys-91, MOD:01149." [PMID:21084637, PRO:HJD]

Yes

organism-modification



PR:000037289

paired box protein Pax-6 isoform 3 unsumoylated 1 (mouse)

mPAX6/iso:3/UnSumo:1


"A paired box protein Pax-6 isoform 3 unsumoylated 1 in mouse. This lacks the sumoylation on the lysine corresponding to position 91 of the amino acid sequence represented by UniProtKB:P63015-3. UniProtKB:P63015-3, Lys-91, PR:000026291." [PMID:21084637, PRO:HJD]


organism-gene



PR:P63016

paired box protein Pax-6 (rat)

rPAX6


"A paired box protein Pax-6 that is encoded in the genome of rat." [OMA:P63016, PRO:DNx]


organism-sequence



PR:P63016-1

paired box protein Pax-6 isoform 1 (rat)

rPAX6/iso:1


"A paired box protein Pax-6 isoform 1 that is encoded in the genome of rat." [PMID:15489334, PMID:24952136, PRO:CNA]

Yes

organism-sequence



PR:P63016-2

paired box protein Pax-6 isoform 2 (rat)

rPAX6/iso:2


"A paired box protein Pax-6 isoform 2 that is encoded in the genome of rat." [PMID:24952136, PRO:CNA]

Yes

sequence



PR:000037280

paired box protein Pax-6 isoform 1

PAX6/iso:1


"A paired box protein Pax-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63015-1 or a 1:1 ortholog thereof." [PMID:16141072, PMID:21084637, PRO:HJD]


organism-sequence



PR:P26367-1

paired box protein Pax-6 isoform 1 (human)

hPAX6/iso:1


"A paired box protein Pax-6 isoform 1 that is encoded in the genome of human." [PMID:7958875, PRO:CNA]


organism-sequence



PR:P63015-1

paired box protein Pax-6 isoform 1 (mouse)

mPAX6/iso:1


"A paired box protein Pax-6 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PMID:21084637, PRO:HJD]

Yes

organism-sequence



PR:P63016-1

paired box protein Pax-6 isoform 1 (rat)

rPAX6/iso:1


"A paired box protein Pax-6 isoform 1 that is encoded in the genome of rat." [PMID:15489334, PMID:24952136, PRO:CNA]

Yes

sequence



PR:000037282

paired box protein Pax-6 isoform 2

PAX6/iso:2


"A paired box protein Pax-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63015-2 or a 1:1 ortholog thereof." [PMID:15489334, PMID:21084637, PRO:HJD]


organism-sequence



PR:P26367-2

paired box protein Pax-6 isoform 2 (human)

hPAX6/iso:2


"A paired box protein Pax-6 isoform 2 that is encoded in the genome of human." [PMID:10954416, PMID:7958875, PRO:CNA]


organism-sequence



PR:P63015-2

paired box protein Pax-6 isoform 2 (mouse)

mPAX6/iso:2


"A paired box protein Pax-6 isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PMID:21084637, PRO:HJD]


organism-sequence



PR:P63016-2

paired box protein Pax-6 isoform 2 (rat)

rPAX6/iso:2


"A paired box protein Pax-6 isoform 2 that is encoded in the genome of rat." [PMID:24952136, PRO:CNA]

Yes

sequence



PR:000037284

paired box protein Pax-6 isoform 3

PAX6/iso:3


"A paired box protein Pax-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63015-3 or a 1:1 ortholog thereof." [PMID:11042159, PMID:21084637, PRO:HJD]


organism-sequence



PR:P63015-3

paired box protein Pax-6 isoform 3 (mouse)

mPAX6/iso:3


"A paired box protein Pax-6 isoform 3 that is encoded in the genome of mouse." [PMID:15489334, PMID:21084637, PRO:HJD]


organism-modification



PR:000037287

paired box protein Pax-6 isoform 3 sumoylated 1 (mouse)

mPAX6/iso:3/Sumo:1


"A paired box protein Pax-6 isoform 3 sumoylated 1 in mouse. UniProtKB:P63015-3, Lys-91, MOD:01149." [PMID:21084637, PRO:HJD]

Yes

organism-modification



PR:000037289

paired box protein Pax-6 isoform 3 unsumoylated 1 (mouse)

mPAX6/iso:3/UnSumo:1


"A paired box protein Pax-6 isoform 3 unsumoylated 1 in mouse. This lacks the sumoylation on the lysine corresponding to position 91 of the amino acid sequence represented by UniProtKB:P63015-3. UniProtKB:P63015-3, Lys-91, PR:000026291." [PMID:21084637, PRO:HJD]


modification



PR:000037286

paired box protein Pax-6 isoform 3 sumoylated 1

PAX6/iso:3/Sumo:1


"A paired box protein Pax-6 isoform 3 that has been sumoylated by SUMO 1 on a Lys residue within the DNA binding domain. Example: UniProtKB:P63015-3, Lys-91, MOD:01149." [PMID:21084637, PRO:HJD]


organism-modification



PR:000037287

paired box protein Pax-6 isoform 3 sumoylated 1 (mouse)

mPAX6/iso:3/Sumo:1


"A paired box protein Pax-6 isoform 3 sumoylated 1 in mouse. UniProtKB:P63015-3, Lys-91, MOD:01149." [PMID:21084637, PRO:HJD]

Yes

modification



PR:000037288

paired box protein Pax-6 isoform 3 unsumoylated 1

PAX6/iso:3/UnSumo:1


"A paired box protein Pax-6 isoform 3 that lacks a sumo modification on a Lys residue within the DNA binding domain. Example: UniProtKB:P63015-3, Lys-91, PR:000026291." [PMID:21084637, PRO:DAN, PRO:HJD]


organism-modification



PR:000037289

paired box protein Pax-6 isoform 3 unsumoylated 1 (mouse)

mPAX6/iso:3/UnSumo:1


"A paired box protein Pax-6 isoform 3 unsumoylated 1 in mouse. This lacks the sumoylation on the lysine corresponding to position 91 of the amino acid sequence represented by UniProtKB:P63015-3. UniProtKB:P63015-3, Lys-91, PR:000026291." [PMID:21084637, PRO:HJD]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037287 mPAX6/iso:3/Sumo:1
UniProtKB:P63015-3, Lys-91, MOD:01149
enablesGO:0043565 sequence-specific DNA binding MGI_ref:4867351; PMID:21084637
PR:P63015-1 mPAX6/iso:1 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4867351; PMID:21084637
PR:P63016-1 rPAX6/iso:1 located_inGO:0005634 nucleus PMID:24952136
PR:P63016-2 rPAX6/iso:2 located_inGO:0005634 nucleus PMID:24952136