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Protein Ontology report - ribonucleoside-diphosphate reductase large subunit
PR:000014305 - http://purl.obolibrary.org/obo/PR_000014305
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000014305   
  PRO nameribonucleoside-diphosphate reductase large subunit 
  Synonyms
PRO-Short-label: EXACT:RRM1
Gene-based: RELATED:RR1
Other: EXACT:ribonucleoside-diphosphate reductase subunit M1 | ribonucleotide reductase large subunit
  Definition"A protein that is a translation product of the human RRM1 gene or a 1:1 ortholog thereof." [PRO:DAN] 
  CommentNote: The fission yeast ortholog is called cdc22. [PRO:CNA, PMID:14648198]. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 10                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2630
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
gene



PR:000014305

ribonucleoside-diphosphate reductase large subunit

RRM1


"A protein that is a translation product of the human RRM1 gene or a 1:1 ortholog thereof." [PRO:DAN]


organism-gene



PR:000036298

ribonucleoside-diphosphate reductase large chain (Schizosaccharomyces pombe)

Spom-cdc22


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of Schizosaccharomyces pombe." [PRO:DAN]


Yes
organism-gene



PR:P07742

ribonucleoside-diphosphate reductase large subunit (mouse)

mRRM1


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of mouse." [OMA:P07742, PRO:DNx]


organism-sequence



PR:P07742-1

ribonucleoside-diphosphate reductase large subunit isoform 1 (mouse)

mRRM1/iso:1


"A ribonucleoside-diphosphate reductase large subunit isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P23921

ribonucleoside-diphosphate reductase large subunit (human)

hRRM1


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:P23921]


organism-sequence



PR:P23921-1

ribonucleoside-diphosphate reductase large subunit isoform 1 (human)

hRRM1/iso:1


"A ribonucleoside-diphosphate reductase large subunit isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000071211

ribonucleoside-diphosphate reductase large subunit cysteinylated 1 (human)

hRRM1/Cyst:1


"A ribonucleoside-diphosphate reductase large subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-26 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Cys-26, MOD:00765." [IEDB_epitope:1055591, PRO:DNx]


organism-modification



PR:000077189

ribonucleoside-diphosphate reductase large subunit methylated 1 (human)

hRRM1/Me:1


"A ribonucleoside-diphosphate reductase large subunit (human) that has been methylated on the residue at the position equivalent to Cys-26 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Cys-26, MOD:00660." [IEDB_epitope:1055592, PRO:DNx]


organism-modification



PR:000080316

ribonucleoside-diphosphate reductase large subunit cysteinylated 2 (human)

hRRM1/Cyst:2


"A ribonucleoside-diphosphate reductase large subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-444 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Cys-444, MOD:00765." [IEDB_epitope:925063, PRO:DNx]


organism-modification



PR:000080346

ribonucleoside-diphosphate reductase large subunit cysteinylated 3 (human)

hRRM1/Cyst:3


"A ribonucleoside-diphosphate reductase large subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-429 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Cys-429, MOD:00765." [IEDB_epitope:1581921, PRO:DNx]


organism-modification



PR:000080609

ribonucleoside-diphosphate reductase large subunit deaminated 1 (human)

hRRM1/Deam:1


"A ribonucleoside-diphosphate reductase large subunit (human) that has been deaminated on the residue at the position equivalent to Asn-85 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Asn-85, MOD:00684." [IEDB_epitope:1581972, PRO:DNx]


organism-modification



PR:000081726

ribonucleoside-diphosphate reductase large subunit deaminated 2 (human)

hRRM1/Deam:2


"A ribonucleoside-diphosphate reductase large subunit (human) that has been deaminated on the residue at the position equivalent to Gln-530 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Gln-530, MOD:00685." [IEDB_epitope:774366, PRO:DNx]


organism-modification



PR:000081907

ribonucleoside-diphosphate reductase large subunit deaminated 3 (human)

hRRM1/Deam:3


"A ribonucleoside-diphosphate reductase large subunit (human) that has been deaminated on the residue at the position equivalent to Gln-678 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Gln-678, MOD:00685." [IEDB_epitope:1982421, PRO:DNx]


organism-modification



PR:000084630

ribonucleoside-diphosphate reductase large subunit methylated 2 (human)

hRRM1/Me:2


"A ribonucleoside-diphosphate reductase large subunit (human) that has been methylated on the residue at the position equivalent to Cys-429 of the amino acid sequence represented by UniProtKB:P23921. UniProtKB:P23921, Cys-429, MOD:00660." [IEDB_epitope:1035603, PRO:DNx]


organism-gene



PR:P36602

ribonucleoside-diphosphate reductase large chain (Schizosaccharomyces pombe 972h-)

Spom972h-cdc22


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P36602, PMID:14648198, PRO:CNA]


organism-gene



PR:P48591

ribonucleoside-diphosphate reductase large subunit (fruit fly)

fly-RRM1


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of fruit fly." [OMA:P48591, PRO:DNx]


organism-gene



PR:P79732

ribonucleoside-diphosphate reductase large subunit (zebrafish)

z-RRM1


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of zebrafish." [OMA:P79732, PRO:DNx]


organism-gene



PR:P9WH75

ribonucleoside-diphosphate reductase subunit alpha (Mycobacterium tuberculosis H37Rv)

RRM1 (MYCTU)


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of Mycobacterium tuberculosis H37Rv." [OMA:P9WH75, PRO:DNx]


organism-gene



PR:Q03604

ribonucleoside-diphosphate reductase large subunit (worm)

RRM1 (worm)


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of worm." [OMA:Q03604, PRO:DNx]


organism-gene



PR:Q54Q71

ribonucleoside-diphosphate reductase large subunit (Dictyostelium discoideum)

Dicty-RRM1


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54Q71, PRO:DNx]


organism-gene



PR:Q9SJ20

ribonucleoside-diphosphate reductase large subunit (Arabidopsis thaliana)

At-RRM1


"A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9SJ20, PRO:DNx]


sequence



PR:000039107

ribonucleoside-diphosphate reductase large subunit isoform 1

RRM1/iso:1


"A ribonucleoside-diphosphate reductase large subunit that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23921-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P07742-1

ribonucleoside-diphosphate reductase large subunit isoform 1 (mouse)

mRRM1/iso:1


"A ribonucleoside-diphosphate reductase large subunit isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P23921-1

ribonucleoside-diphosphate reductase large subunit isoform 1 (human)

hRRM1/iso:1


"A ribonucleoside-diphosphate reductase large subunit isoform 1 that is encoded in the genome of human." [PRO:DNx]


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RRM1 forms found in complexes   

RRM1 Component
Complexes
PR:000036298 Spom-cdc22 PR:000027720 ribonucleoside-diphosphate reductase complex (Schizosaccharomyces pombe)