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Protein Ontology report - nuclear factor NF-kappa-B p105 subunit proteolytic cleavage product
PR:000018519 - http://purl.obolibrary.org/obo/PR_000018519
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000018519   
  PRO namenuclear factor NF-kappa-B p105 subunit proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:NFKB1/ClvPrd
  Definition"A nuclear factor NF-kappa-B p105 subunit that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000001754 nuclear factor NF-kappa-B p105 subunit
PR:000018264 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
modification



PR:000018519

nuclear factor NF-kappa-B p105 subunit proteolytic cleavage product

NFKB1/ClvPrd


"A nuclear factor NF-kappa-B p105 subunit that has been processed by proteolytic cleavage." [PRO:DNx]


modification



PR:000001757

nuclear factor NF-kappa-B p50 subunit

NFKBp50


"A nuclear factor NF-kappa-B p105 subunit isoform 1 that has been processed by proteolytic cleavage to remove the C-terminal domain of p105 downstream from the 23-residue glycine rich region (GRR). Example: UniProtKB:P19838-1, 1-433." [PMID:2203532, PMID:8628291, PRO:DAN, PRO:JAN]


organism-modification



PR:000028540

nuclear factor NF-kappa-B p50 subunit (mouse)

mNFKBp50


"A nuclear factor NF-kappa-B p50 subunit in mouse. Example: UniProtKB:P25799-1, 1-431." [PMID:2203532, PRO:CNA]


Yes
organism-modification



PR:000035834

nuclear factor NF-kappa-B p50 subunit (human)

hNFKBp50


"A nuclear factor NF-kappa-B p50 subunit in human. Example: UniProtKB:P19838-1, 1-433." [PRO:DNx, UniProtKB:P19838]

Yes

Yes
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NFKB1/ClvPrd forms found in complexes   

NFKB1/ClvPrd Component
Complexes
PR:000028540 mNFKBp50 PR:000028542 NF-kappaB p50/p65 complex (mouse)
PR:000035834 hNFKBp50 PR:000035835 NF-kappaB p50/p65 complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035834 hNFKBp50
Example: UniProtKB:P19838-1, 1-433
acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894