Protein Ontology

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Protein Ontology report - growth/differentiation factor 5 isoform 1, signal peptide removed form

PR:000021914 - http://purl.obolibrary.org/obo/PR_000021914

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000021914

PRO name

growth/differentiation factor 5 isoform 1, signal peptide removed form

Synonyms

PRO-Short-label:

EXACT:

GDF5/iso:1/SigPep-

Definition

"A growth/differentiation factor 5 isoform 1 that has had the signal peptide removed." [PRO:DNx]

PRO Category

modification

Parent

PR:000000436 growth/differentiation factor 5 isoform 1

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	2	Organism-Modification	1

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

modification

PR:000021914 growth/differentiation factor 5 isoform 1, signal peptide removed form

GDF5/iso:1/SigPep-

modification

PR:000000640 growth/differentiation factor 5 isoform 1 cleaved 1

GDF5/iso:1/Clv:1

organism-modification

PR:000036543 growth/differentiation factor 5 isoform 1 cleaved 1 (human)

hGDF5/iso:1/Clv:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036543 hGDF5/iso:1/Clv:1 UniProtKB:P43026-1, 382-501	enables	GO:0005102 signaling receptor binding	PMID:15752764; PMID:15890363
		GO:0005515 protein binding	PMID:9288098
		GO:0008083 growth factor activity	PMID:8589725
		GO:0042803 protein homodimerization activity	PMID:15752764; PMID:8962721
	located_in	GO:0005615 extracellular space	PMID:16532400