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Protein Ontology report - lefty 1 proteolytic cleavage product
PR:000025431 - http://purl.obolibrary.org/obo/PR_000025431
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025431   
  PRO namelefty 1 proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:LEFTY1/ClvPrd
  Definition"A lefty 1 that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000000287 lefty 1
PR:000018264 proteolytic cleavage product
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
modification



PR:000025431

lefty 1 proteolytic cleavage product

LEFTY1/ClvPrd


"A lefty 1 that has been processed by proteolytic cleavage." [PRO:DNx]


modification



PR:000000643

lefty 1 isoform 1 cleaved 1

LEFTY1/iso:1/Clv:1


"A lefty 1 isoform 1 that is the C-terminal part after processing by proteolytic cleavage at the first dibasic RxxR cleavage site within the propeptide region." [PMID:11278322, PMID:18039650]


organism-modification



PR:000036546

lefty 1 isoform 1 cleaved 1 (human)

hLEFTY1/iso:1/Clv:1


"A lefty 1 isoform 1 cleaved 1 in human. UniProtKB:O75610-1, 77-366." [PMID:11278322, PRO:CNA]

Yes

organism-modification



PR:000036547

lefty 1 isoform 1 cleaved 1 (mouse)

mLEFTY1/iso:1/Clv:1


"A lefty 1 isoform 1 cleaved 1 in mouse. UniProtKB:Q64280-1, 77-368." [PMID:15004567, PMID:18039650, PRO:CNA]

Yes

modification



PR:000000644

lefty 1 isoform 1 cleaved 2

LEFTY1/iso:1/Clv:2


"A lefty 1 isoform 1 that is the C-terminal part after processing by proteolytic cleavage at the second dibasic RxxR cleavage site within the propeptide region." [PMID:11278322]


organism-modification



PR:000036548

lefty 1 isoform 1 cleaved 2 (human)

hLEFTY1/iso:1/Clv:2


"A lefty 1 isoform 1 cleaved 2 in human. UniProtKB:O75610-1, 135-366." [PMID:11278322, PRO:CNA]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036546 hLEFTY1/iso:1/Clv:1
UniProtKB:O75610-1, 77-366
located_inGO:0005615 extracellular space PMID:11278322
PR:000036547 mLEFTY1/iso:1/Clv:1
UniProtKB:Q64280-1, 77-368
acts_upstream_of_or_withinGO:0008285 negative regulation of cell population proliferation PMID:15004567
GO:0009948 anterior/posterior axis specification PMID:15004567
located_inGO:0005615 extracellular space PMID:18039650
PR:000036548 hLEFTY1/iso:1/Clv:2
UniProtKB:O75610-1, 135-366
acts_upstream_of_or_withinGO:0043406 positive regulation of MAP kinase activity PMID:11278322
located_inGO:0005615 extracellular space PMID:11278322