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Protein Ontology report - Rho-associated protein kinase 2 proteolytic cleavage product

PR:000025436 - http://purl.obolibrary.org/obo/PR_000025436

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000025436

PRO name

Rho-associated protein kinase 2 proteolytic cleavage product

Synonyms

PRO-Short-label:

EXACT:

ROCK2/ClvPrd

Definition

"A Rho-associated protein kinase 2 that has been processed by proteolytic cleavage." [PRO:DNx]

PRO Category

modification

Parent

PR:000000121 Rho-associated protein kinase 2
PR:000018264 proteolytic cleavage product

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	2	Organism-Modification	1

Term Hierarchy
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DAG:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

modification

PR:000025436 Rho-associated protein kinase 2 proteolytic cleavage product

ROCK2/ClvPrd

modification

PR:000000564 Rho-associated protein kinase 2 isoform 1 cleaved 1

ROCK2/iso:1/Clv:1

organism-modification

PR:000036477 Rho-associated protein kinase 2 isoform 1 cleaved 1 (human)

hROCK2/iso:1/Clv:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000036477 hROCK2/iso:1/Clv:1 UniProtKB:O75116-1, 1-1131	acts_upstream_of_or_within	GO:0006468 protein phosphorylation	PMID:15699075
	acts_upstream_of_or_within	GO:0030036 actin cytoskeleton organization	PMID:15699075
	enables	increased GO:0004674 protein serine/threonine kinase activity relative to PR:000002530 ROCK2/iso:1/UnMod	PMID:15699075
	located_in	GO:0005622 intracellular anatomical structure	PMID:15699075