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Protein Ontology report - tyrosine-protein kinase SYK isoform 1 phosphorylated 1

PR:000025833 - http://purl.obolibrary.org/obo/PR_000025833

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000025833

PRO name

tyrosine-protein kinase SYK isoform 1 phosphorylated 1

Synonyms

PRO-Short-label:

EXACT:

SYK/iso:1/Phos:1

Definition

"A tyrosine-protein kinase SYK isoform 1 that has been phosphorylated on several Tyr residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lyn. Example: UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048." [PMID:15536084, PRO:CNA, PRO:DAN]

PRO Category

modification

Parent

PR:000025832 tyrosine-protein kinase SYK isoform 1
PR:000037070 phosphoprotein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	1	Organism-Modification	1

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

modification

PR:000025833 tyrosine-protein kinase SYK isoform 1 phosphorylated 1

SYK/iso:1/Phos:1

organism-modification

PR:000025834 tyrosine-protein kinase SYK isoform 1 phosphorylated 1 (mouse)

mSYK/iso:1/Phos:1

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000025834 mSYK/iso:1/Phos:1 UniProtKB:P48025-1, Tyr-317/Tyr-342/Tyr-346, MOD:00048	acts_upstream_of_or_within	GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	PMID:15536084
	enables	GO:0019901 protein kinase binding with PR:P09769 FGR	PMID:15536084
		GO:0031625 ubiquitin protein ligase binding	PMID:15536084
		GO:0043548 phosphatidylinositol 3-kinase binding	PMID:15536084