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Protein Ontology report - protein Mdm4 isoform 1
PR:000025835 - http://purl.obolibrary.org/obo/PR_000025835
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000025835   
  PRO nameprotein Mdm4 isoform 1 
  Synonyms
PRO-Short-label: EXACT:MDM4/iso:1
  Definition"A protein Mdm4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15151-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000010268 protein Mdm4
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000025835

protein Mdm4 isoform 1

MDM4/iso:1


"A protein Mdm4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15151-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:O15151-1

protein Mdm4 isoform 1 (human)

hMDM4/iso:1


"A protein Mdm4 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000025837

protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)

hMDM4/iso:1/PhosUbiq:1


"A protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 in human. UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148." [PMID:16511560, PRO:JAN]

Yes

organism-sequence



PR:Q5XIN1-1

protein Mdm4 isoform 1 (rat)

rMDM4/iso:1


"A protein Mdm4 isoform 1 that is encoded in the genome of rat." [PRO:CNA]


organism-sequence



PR:Q99L86

protein Mdm4 isoform 1 (mouse)

mMDM4/iso:1


"A protein Mdm4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000025836

protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1

MDM4/iso:1/PhosUbiq:1


"A protein Mdm4 isoform 1 that has been phosphorylated by Chk2, and ubiquitinated by MDM2. Example: UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148." [PMID:16511560, PRO:CNA, PRO:DAN]


organism-modification



PR:000025837

protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 (human)

hMDM4/iso:1/PhosUbiq:1


"A protein Mdm4 isoform 1 phosphorylated and ubiquitinated 1 in human. UniProtKB:O15151-1, Ser-367, MOD:00046|MOD:01148." [PMID:16511560, PRO:JAN]

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediatorPR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511560

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0071889 14-3-3 protein bindingPR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572
PR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511572

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:000025837 hMDM4/iso:1/PhosUbiq:1 PMID:16511560