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Protein Ontology report - TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
PR:000025959 -
http://purl.obolibrary.org/obo/PR_000025959
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000025959
PRO name
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hTGFBR1/iso:1/SigPep-/Phos:1
PRO-proteoform-std
:
EXACT:
UniProtKB:P36897-1
, 34-503, Ser-165/Ser-187/Ser-189/Ser-191,
MOD:00046
|Thr-185/Thr-186,
MOD:00047
PRO-proteoform-ftid
:
EXACT:
PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191,
MOD:00046
|Thr-185/Thr-186,
MOD:00047
Definition
"A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human. Phosphorylation occurs by the action of active TGF-beta receptor type-2 within the GS-motifs.
UniProtKB:P36897-1
, 34-503, Ser-165/Ser-187/Ser-189/Ser-191,
MOD:00046
|Thr-185/Thr-186,
MOD:00047
." [
PMID:7774578
,
PMID:8947046
]
Comment
Kinase=("TGFBR2";
PR:000025962
; Ser-165/Thr-185/Thr-186/Ser-187/Ser-189/Ser-191).
PRO Category
organism-modification
Parent
PR:000000523
TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
PR:000036432
TGF-beta receptor type-1 isoform 1, signal peptide removed form (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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hTGFBR1/iso:1/SigPep-/Phos:1
forms found in complexes
hTGFBR1/iso:1/SigPep-/Phos:1
Component
Complexes
PR:000025959
hTGFBR1/iso:1/SigPep-/Phos:1
PR:000025961
transforming growth factor beta type I receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000025959
hTGFBR1/iso:1/SigPep-/Phos:1
UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047
acts_upstream_of_or_within
GO:0006468
protein phosphorylation
PMID:7774578
GO:0007165
signal transduction
PMID:8242743
GO:0007181
transforming growth factor beta receptor complex assembly
PMID:8947046
enables
GO:0005025
transforming growth factor beta receptor activity, type I
PMID:7774578
;
PMID:8947046
located_in
GO:0005886
plasma membrane
PMID:8947046