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Protein Ontology report - TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human)
PR:000025959 - http://purl.obolibrary.org/obo/PR_000025959
 
    Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000025959   
  PRO nameTGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hTGFBR1/iso:1/SigPep-/Phos:1
PRO-proteoform-std: EXACT:UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047
PRO-proteoform-ftid: EXACT:PRO_0000024423, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047
  Definition"A TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human. Phosphorylation occurs by the action of active TGF-beta receptor type-2 within the GS-motifs. UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047." [PMID:7774578, PMID:8947046
  CommentKinase=("TGFBR2"; PR:000025962; Ser-165/Thr-185/Thr-186/Ser-187/Ser-189/Ser-191). 
  PRO Categoryorganism-modification 
  ParentPR:000000523 TGF-beta receptor type-1 isoform 1, signal peptide removed phosphorylated 1
PR:000036432 TGF-beta receptor type-1 isoform 1, signal peptide removed form (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS:
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hTGFBR1/iso:1/SigPep-/Phos:1 forms found in complexes   

hTGFBR1/iso:1/SigPep-/Phos:1 Component
Complexes
PR:000025959 hTGFBR1/iso:1/SigPep-/Phos:1 PR:000025961 transforming growth factor beta type I receptor homodimeric complex phosphorylated form (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025959 hTGFBR1/iso:1/SigPep-/Phos:1
UniProtKB:P36897-1, 34-503, Ser-165/Ser-187/Ser-189/Ser-191, MOD:00046|Thr-185/Thr-186, MOD:00047
acts_upstream_of_or_withinGO:0006468 protein phosphorylation PMID:7774578
GO:0007165 signal transduction PMID:8242743
GO:0007181 transforming growth factor beta receptor complex assembly PMID:8947046
enablesGO:0005025 transforming growth factor beta receptor activity, type I PMID:7774578; PMID:8947046
located_inGO:0005886 plasma membrane PMID:8947046