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Protein Ontology report - 5-aminolevulinate synthase
PR:000026125 - http://purl.obolibrary.org/obo/PR_000026125
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000026125   
  PRO name5-aminolevulinate synthase 
  Synonyms
Other: EXACT:5-aminolevulinic acid synthase | ALAS
  Definition"A PLP-dependent alpha-oxoamine synthase whose functional form is the first enzyme in the pathway for synthesis of all tetrapyrroles in non-photosynthetic eukaryotes and alpha-proteobacteria. ALAS catalyzes the decarboxylative condensation of glycine and succinyl-CoA, yielding 5-aminolevulinic acid, free coenzyme-A and CO2." [PMID:13598764, PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000026124 PLP-dependent alpha-oxoamine synthase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 11                                        
         Sequence2                                                  Organism-Sequence 10                                        
         Modification2                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF000444
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
family



PR:000026125 5-aminolevulinate synthase

hMCCC2/var:MCCB IVS3+5G->T


gene



PR:000003916 5-aminolevulinate synthase, non-specific, mitochondrial

ALAS1


organism-gene



PR:P07997 5-aminolevulinate synthase, non-specific, mitochondrial (chicken)

chick-ALAS1


organism-gene



PR:P13195 5-aminolevulinate synthase, non-specific, mitochondrial (rat)

rALAS1


organism-sequence



PR:P13195-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat)

rALAS1/iso:1


organism-gene



PR:P13196 5-aminolevulinate synthase, non-specific, mitochondrial (human)

hALAS1


organism-sequence



PR:P13196-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform h1 (human)

hALAS1/iso:h1


organism-sequence



PR:P13196-2 5-aminolevulinate synthase, non-specific, mitochondrial isoform h2 (human)

hALAS1/iso:h2


organism-modification



PR:000046304 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)

hALAS1/TransPep-


organism-modification



PR:000046305 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)

hALAS1/TransPep-/PyrdoxLys+


organism-modification



PR:000046305 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)

hALAS1/TransPep-/PyrdoxLys+


organism-modification



PR:000066761 5-aminolevulinate synthase, non-specific, mitochondrial methylated 1 (human)

hALAS1/Me:1


organism-modification



PR:000078022 5-aminolevulinate synthase, non-specific, mitochondrial methylated 2 (human)

hALAS1/Me:2


organism-gene



PR:Q8VC19 5-aminolevulinate synthase, non-specific, mitochondrial (mouse)

mALAS1


organism-sequence



PR:Q8VC19-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse)

mALAS1/iso:1


sequence



PR:000042113 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1

ALAS1/iso:1


organism-sequence



PR:P13195-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (rat)

rALAS1/iso:1


organism-sequence



PR:Q8VC19-1 5-aminolevulinate synthase, non-specific, mitochondrial isoform 1 (mouse)

mALAS1/iso:1


modification



PR:000018945 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form

ALAS1/TransPep-


organism-modification



PR:000046304 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed form (human)

hALAS1/TransPep-


organism-modification



PR:000046305 5-aminolevulinate synthase, non-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)

hALAS1/TransPep-/PyrdoxLys+


gene



PR:000003917 5-aminolevulinate synthase, erythroid-specific, mitochondrial

ALAS2


organism-gene



PR:O14092 5-aminolevulinate synthase, mitochondrial (Schizosaccharomyces pombe 972h-)

Spom972h-ALAS2


organism-gene



PR:P08680 5-aminolevulinate synthase, erythroid-specific, mitochondrial (mouse)

mALAS2


organism-sequence



PR:P08680-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)

mALAS2/iso:1


organism-gene



PR:P09950 5-aminolevulinate synthase, mitochondrial (yeast)

yALAS2


organism-gene



PR:P22557 5-aminolevulinate synthase, erythroid-specific, mitochondrial (human)

hALAS2


organism-sequence



PR:P22557-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)

hALAS2/iso:1


organism-sequence



PR:P22557-2 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h2 (human)

hALAS2/iso:h2


organism-sequence



PR:P22557-3 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h3 (human)

hALAS2/iso:h3


organism-sequence



PR:P22557-4 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform h4 (human)

hALAS2/iso:h4


organism-modification



PR:000046306 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)

hALAS2/TransPep-/PyrdoxLys+


organism-gene



PR:Q54UX3 5-aminolevulinate synthase (Dictyostelium discoideum)

Dicty-ALAS2


organism-gene



PR:Q63147 5-aminolevulinate synthase, erythroid-specific, mitochondrial (rat)

rALAS2


organism-sequence



PR:Q63147-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)

rALAS2/iso:1


organism-gene



PR:Q9YHT4 5-aminolevulinate synthase, erythroid-specific, mitochondrial (zebrafish)

z-ALAS2


sequence



PR:000039074 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1

ALAS2/iso:1


organism-sequence



PR:P08680-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (mouse)

mALAS2/iso:1


organism-sequence



PR:P22557-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (human)

hALAS2/iso:1


organism-sequence



PR:Q63147-1 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform 1 (rat)

rALAS2/iso:1


modification



PR:000018947 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed form

ALAS2/TransPep-


organism-modification



PR:000046306 5-aminolevulinate synthase, erythroid-specific, mitochondrial, transit peptide removed pyridoxal phosphate lysine form (human)

hALAS2/TransPep-/PyrdoxLys+