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Protein Ontology report - E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1
PR:000026188 -
http://purl.obolibrary.org/obo/PR_000026188
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000026188
PRO name
E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1
Synonyms
PRO-Short-label
:
EXACT:
CBL/iso:1/Phos:1
Other
:
RELATED:
phospho-CLB
Definition
"An E3 ubiquitin-protein ligase CBL isoform 1 that has been phosphorylated by tyrosine kinase receptors, such as EGFR or INSR. This tyrosine phosphorylation is necessary for activation of the ubiquitin ligase activity. Example:
UniProtKB:P22681-1
, Tyr-371,
MOD:00048
." [
PMID:11997497
,
PMID:15117950
, PRO:CNx,
Reactome:R-HSA-182923
,
Reactome:R-HSA-182940
]
PRO Category
modification
Parent
PR:000026186
E3 ubiquitin-protein ligase CBL isoform 1
PR:000037070
phosphoprotein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000026188
E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1
CBL/iso:1/Phos:1
"An E3 ubiquitin-protein ligase CBL isoform 1 that has been phosphorylated by tyrosine kinase receptors, such as EGFR or INSR. This tyrosine phosphorylation is necessary for activation of the ubiquitin ligase activity. Example: UniProtKB:P22681-1, Tyr-371, MOD:00048." [PMID:11997497, PMID:15117950, PRO:CNx, Reactome:R-HSA-182923, Reactome:R-HSA-182940]
organism-modification
PR:000026223
E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1 (human)
hCBL/iso:1/Phos:1
"An E3 ubiquitin-protein ligase CBL isoform 1 phosphorylated 1 in human. UniProtKB:P22681-1, Tyr-371, MOD:00048." [PMID:11997497, PMID:15117950, PRO:CNx, Reactome:R-HSA-182923, Reactome:R-HSA-182940]