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Protein Ontology report - prelamin-A/C isoform A
PR:000026539 - http://purl.obolibrary.org/obo/PR_000026539
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000026539   
  PRO nameprelamin-A/C isoform A 
  Synonyms
PRO-Short-label: EXACT:LMNA/iso:A
Other: EXACT:prelamin-A/C isoform 1
  Definition"A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-1 or a 1:1 ortholog thereof." [PMID:10080180] 
  PRO Categorysequence 
  ParentPR:000009859 prelamin-A/C
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
sequence


PR:000026539 prelamin-A/C isoform A
LMNA/iso:A

organism-sequence


PR:P02545-1 prelamin-A/C isoform A (human)
hLMNA/iso:A
Yes
organism-sequence


PR:P48678-1 prelamin-A/C isoform A (mouse)
mLMNA/iso:A

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007517 muscle organ developmentPR:P02545-1 hLMNA/iso:A PMID:10080180

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005198 structural molecule activityPR:P02545-1 hLMNA/iso:A PMID:8344919
PR:P02545-1 hLMNA/iso:A PMID:8344919
PR:P02545-1 hLMNA/iso:A PMID:8344919
PR:P02545-1 hLMNA/iso:A PMID:8344919
GO:0005515 protein bindingPR:P02545-1 hLMNA/iso:A PMID:10381623

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005635 nuclear envelopePR:P02545-1 hLMNA/iso:A PMID:3453101
GO:0005638 lamin filamentPR:P02545-1 hLMNA/iso:A PMID:10080180
GO:0005652 nuclear laminaPR:P02545-1 hLMNA/iso:A PMID:8344919
GO:0005882 intermediate filamentPR:P02545-1 hLMNA/iso:A PMID:8344919
GO:0048471 perinuclear region of cytoplasmPR:P02545-1 hLMNA/iso:A PMID:10080180