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Protein Ontology report - prelamin-A/C isoform C
PR:000026541 - http://purl.obolibrary.org/obo/PR_000026541
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000026541   
  PRO nameprelamin-A/C isoform C 
  Synonyms
PRO-Short-label: EXACT:LMNA/iso:C
Other: EXACT:prelamin-A/C isoform 2
  Definition"A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-2 or a 1:1 ortholog thereof." [PMID:10080180
  PRO Categorysequence 
  ParentPR:000009859 prelamin-A/C
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000026541

prelamin-A/C isoform C

LMNA/iso:C


"A prelamin-A/C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02545-2 or a 1:1 ortholog thereof." [PMID:10080180]


organism-sequence



PR:P02545-2

prelamin-A/C isoform C (human)

hLMNA/iso:C


"A prelamin-A/C isoform C that is encoded in the genome of human." [PMID:10080180]

Yes

organism-modification



PR:000060751

prelamin-A/C isoform C phosphorylated 1 (human)

hLMNA/iso:C/Phos:1


"A prelamin-A/C isoform C (human) that has been phosphorylated on the residue at the position equivalent to Ser-395 of the amino acid sequence represented by UniProtKB:P02545-2. UniProtKB:P02545-2, Ser-395, MOD:00046." [PRO:DNx, Reactome:R-HSA-5228740]


organism-modification



PR:000060980

prelamin-A/C isoform C phosphorylated 2 (human)

hLMNA/iso:C/Phos:2


"A prelamin-A/C isoform C (human) that has been phosphorylated on the residues at the positions equivalent to Ser-22 and Ser-395 of the amino acid sequence represented by UniProtKB:P02545-2. UniProtKB:P02545-2, Ser-22/Ser-395, MOD:00046." [PRO:DNx, Reactome:R-HSA-5229019]


organism-sequence



PR:P48678-2

prelamin-A/C isoform C (mouse)

mLMNA/iso:C


"A prelamin-A/C isoform C that is encoded in the genome of mouse." [PMID:2719959, PRO:HJD]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P02545-2 hLMNA/iso:C acts_upstream_of_or_withinGO:0007517 muscle organ development PMID:10080180
enablesGO:0005198 structural molecule activity PMID:8344919
GO:0005198 structural molecule activity PMID:8344919
GO:0005515 protein binding PMID:10381623
GO:0005515 protein binding PMID:10381623
located_inGO:0005635 nuclear envelope PMID:3453101
GO:0005638 lamin filament PMID:10080180
GO:0005652 nuclear lamina PMID:8344919
GO:0005882 intermediate filament PMID:8344919
GO:0048471 perinuclear region of cytoplasm PMID:10080180