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Protein Ontology report - double-stranded RNA-activated factor 1 complex
PR:000027110 - http://purl.obolibrary.org/obo/PR_000027110
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027110   
  PRO namedouble-stranded RNA-activated factor 1 complex 
  Synonyms
Other: EXACT:draf1 complex | dsRNA-activated factor 1 | IRF3-P dimer:CBP/p300
  Definition"A transcription factor complex that binds to a DNA target containing the type I interferon-stimulated response element and induces transcription of responsive genes. A multimeric transcription factor containing the interferon regulatory factor 3 (IRF-3) protein and one of the histone acetyl transferases, CREB binding protein (CBP) or p300 (CBP/p300)." [PMID:10805757, PRO:CNA, TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0005667 transcription factor complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
complex


PR:000027110
double-stranded RNA-activated factor 1 complex
m(CBP-p300)
"A transcription factor complex that binds to a DNA target containing the type I interferon-stimulated response element and induces transcription of responsive genes. A multimeric transcription factor containing the interferon regulatory factor 3 (IRF-3) protein and one of the histone acetyl transferases, CREB binding protein (CBP) or p300 (CBP/p300)." [PMID:10805757, PRO:CNA, TLR:AMM]

organism-complex


PR:000027111
double-stranded RNA-activated factor 1 complex (human)
m(CBP-p300)
"A double-stranded RNA-activated factor 1 complex whose components are encoded in the genome of human." [PMID:10805757, PRO:CNA, TLR:AMM]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027111 m(CBP-p300) acts_upstream_of_or_withinGO:0034340 response to type I interferon PMID:10805757
enablesGO:0043565 sequence-specific DNA binding PMID:10805757
located_inGO:0005634 nucleus PMID:10805757